23 Recruiting Trials

Clinical Trials
for Diabetes in Nebraska

23 clinical trials for Diabetes are currently recruiting participants at study sites in Nebraska. Study-related care is provided at no cost.

23
Recruiting trials
19
Study sites
6
Cities
15
Industry-sponsored
7
Phase 2
8
Phase 3

Diabetes clinical trials in Nebraska: what to expect

Diabetes is one of the largest areas of clinical research, and the trials differ a great deal by type. Type 2 studies most often test new glucose-lowering or weight-reducing medicines, once-weekly insulins, and combinations with GLP-1 drugs, in people whose A1c is above goal on their current treatment. Type 1 studies test automated insulin delivery systems, immune therapies for people recently diagnosed or at high risk, and cell-based approaches. Others focus on the complications: kidney disease, eye disease, nerve pain and foot ulcers.

In Nebraska, recruiting diabetes studies are concentrated in Omaha, Lincoln, Fremont and Elkhorn, with sites in 2 other cities. 15 of the 23 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who diabetes trials usually look for

Type 2 trials typically ask for a confirmed diagnosis, an A1c in a stated range (often between 7 and 10.5 percent) and a stable dose of your current medicines for at least a few months. Many exclude recent insulin use, a recent heart attack or stroke, or kidney function below a cut-off. Type 1 trials are often limited by time since diagnosis and by age, and some enroll children and teenagers with a parent's consent.

You do not need to know your A1c or kidney numbers to ask about a trial; the site measures them at screening.

What taking part involves

Screening includes blood work and a review of your history. Medicine trials usually last six months to three years with visits every one to three months, and many provide a glucose monitor and supplies for the duration. Some compare a new drug with a standard one rather than a placebo, so everyone receives active treatment; others include a placebo arm, and the consent form says which. Study drugs, devices, visits and labs are provided at no cost, and most trials pay for time and travel.

Questions worth asking the study team

Whether you would stay on your current medicines; whether there is a placebo group; how often visits are and whether any can be done remotely; and whether your own doctor will receive the results of study labs. If you have type 1 diabetes, ask whether the study uses your own pump or monitor.

Showing 20 of 23 recruiting Diabetes trials in Nebraska

A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus
PHASE3 Birmingham, Alabama +4 sites NCT07662213
This trial is looking for adults with type 2 diabetes who struggle to manage their condition. Participants will compare the effectiveness of a new drug, elecoglipron, with an existing treatment, semaglutide.
Recruiting
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
PHASE3 Anniston, Alabama +4 sites NCT07064473
This trial is looking for adults with type 2 diabetes, high blood pressure, and heart disease. Participants will take either the study medication or a placebo daily for up to 4 years.
Recruiting
Efficacy and Safety of Ribupatide Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes
PHASE3 Cullman, Alabama +4 sites NCT07284901
This trial is looking for people with obesity or overweight who also have type 2 diabetes. Participants will receive a weekly injection of ribupatide to see how it affects their weight and blood sugar levels.
Recruiting
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin
PHASE3 Sun City, Arizona +4 sites NCT07662135
This trial is looking for adults with type 2 diabetes and kidney problems. Participants will take either elecoglipron or a placebo while continuing their diabetes medications.
Recruiting
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications
PHASE3 Birmingham, Alabama +4 sites NCT07797335
This trial is looking for adults with type 2 diabetes who are at high risk for heart problems. Participants will receive injections of either zenagamtide or insulin glargine once a week to see which works better for controlling blood sugar and weight.
Recruiting
A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus
PHASE3 Huntsville, Alabama +4 sites NCT07662109
This trial is looking for adults with Type 2 Diabetes who have been managing their condition for at least three months but still need better control. They're particularly interested in those whose blood sugar levels are in a specific range and who have a body weight that meets certain guidelines. However, they’re not accepting people with certain serious health issues, like a history of severe low blood sugar or specific types of diabetes other than Type 2.
Recruiting
Study to Evaluate HM15275 in Subjects With Type 2 Diabetes Mellitus
PHASE2 Mesa, Arizona +4 sites NCT07527650
This trial is looking for adults with type 2 diabetes to test a new treatment called HM15275. Participants will be monitored for 36 weeks to see how well the treatment works and if it is safe.
Recruiting
Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)
PHASE2 Chandler, Arizona +4 sites NCT07296484
This trial is looking for adults who are at least 18 years old and have type 2 diabetes that isn’t well controlled. They should have been on stable diabetes medications for a while and show signs of high cortisol levels. However, it won't include anyone who just started having diabetes, has serious low blood sugar issues, or works night shifts regularly.
Recruiting
A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes
PHASE2 Birmingham, Alabama +4 sites NCT05762107
This trial is looking for adults with type 1 diabetes who experience low blood sugar at night. Participants will receive either the study drug ZT-01 or a placebo for two weeks while using a glucose monitor to track their blood sugar levels.
Recruiting
HP-211 Safety and Proof of Concept Dose Ranging Study in Patients With Type 2 Diabetes
PHASE2 Canoga Park, California +4 sites NCT07546929
This trial is looking for people with type 2 diabetes to test a new treatment. Participants need to have been diagnosed for a certain period and may have to have been on specific diabetes medications before joining.
Recruiting
PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes
PHASE4 Huntsville, Alabama +4 sites NCT05390892
This trial is looking for people with type 2 diabetes and heart disease or at high risk for heart disease. Participants will take one of two medications and will be monitored for heart, kidney, and death-related events over time.
Recruiting
Safety and Efficacy of Adjunct Therapies in Adults With Type 1 Diabetes: Multicenter, Registry Study
N/A Newport Beach, California +4 sites NCT07676565
This trial is looking for adults with Type 1 Diabetes who have been prescribed certain medications as part of their care. Participants will be monitored for one year to see how these treatments work alongside insulin.
Recruiting
Skeletal Effects of Type 1 Diabetes on Low-Trauma Fracture Risk
N/A Omaha, Nebraska NCT05701254
This trial is looking for women with Type 1 Diabetes who are willing to help researchers understand how diabetes affects bone health. Participants will provide blood samples and undergo a procedure to take samples of their bone tissue.
Recruiting
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
NA Chandler, Arizona +4 sites NCT06112418
This trial is looking for older adults with diabetes or risk factors for heart disease. Participants will be randomly assigned to receive different types of care to see which approach is better at preventing heart problems.
Recruiting
Blood Markers of Early Pancreas Cancer
N/A Omaha, Nebraska NCT03568630
This trial is looking for people at higher risk for pancreatic cancer to help find blood markers that could improve early detection. Participants will need to visit Omaha, NE twice a year to provide blood samples.
Recruiting
A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
PHASE3 Birmingham, Alabama +4 sites NCT07654374
This trial is looking for adults with obesity or overweight who also have type 2 diabetes. Participants will take either the drug aleniglipron or a placebo for 76 weeks to assess its effects.
Recruiting
A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight
PHASE3 Fairhope, Alabama +4 sites NCT07784270
This trial is looking for adults with type 2 diabetes and obesity or being overweight. Participants will take AZD6234 or a placebo for 68 weeks to see how it affects their body weight.
Recruiting
Study of Olatorepatide in Adult Participants Living With Overweight or Obesity Without Diabetes
PHASE2 Mobile, Alabama +4 sites NCT07685808
This trial is looking for adults who are overweight or obese but do not have diabetes. Participants will take an experimental drug called olatorepatide to see how safe it is and how it works in the body.
Recruiting
Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes
PHASE4 Phoenix, Arizona +4 sites NCT02915198
This trial is looking for veterans who are between 18 and 80 years old, have pre-diabetes, and have heart or blood vessel issues. They're not including anyone who has recently used certain diabetes medications or has severe kidney problems, liver disease, or other serious health conditions. It's important that participants haven't had recent severe blood sugar issues or any bad reactions to the medication being tested.
Recruiting

Where the Diabetes studies are in Nebraska

  • University of Nebraska Medical Center, Omaha5 trials
  • Research Site, Omaha3 trials
  • Methodist Physicians Clinic, Fremont2 trials
  • Omaha VA Nebraska-Western Iowa Health Care System, Omaha, NE, Omaha2 trials
  • ACCOMPLISH-2 Research Site, Omaha1 trial
  • Bryan Heart, Lincoln1 trial

Counts are recruiting studies listing at least one site in Nebraska, from ClinicalTrials.gov, refreshed every two days.

Diabetes clinical trials in Nebraska: common questions

How many Diabetes clinical trials are recruiting in Nebraska?
TrialFinder currently lists 23 recruiting Diabetes clinical trials with study sites in Nebraska. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Diabetes clinical trials located in Nebraska?
Study sites for the Diabetes trials listed on this page include Omaha, Grand Island. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Diabetes clinical trial in Nebraska?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Diabetes trials in Nebraska also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Diabetes clinical trial in Nebraska?
Each study sets its own criteria based on age, Diabetes diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Can I join a diabetes clinical trial if I am already on medication?
Usually yes. Most type 2 diabetes trials enroll people on metformin or other oral medicines and test a new treatment on top of them; some require a stable dose for a few months first. Trials that exclude insulin or a specific drug say so in their criteria.
Do I need to know my A1c to apply?
No. Trials state an A1c range, but the study site measures it at the screening visit. You only need to know that you have been diagnosed and which type.
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Diabetes clinical trials study new treatments for Type 1, Type 2, and gestational diabetes, including insulin therapies, diet interventions, and islet-cell transplants.

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