22 Recruiting Trials

Clinical Trials
for Asthma in Colorado

22 clinical trials for Asthma are currently recruiting participants at study sites in Colorado. Study-related care is provided at no cost.

22
Recruiting trials
19
Study sites
4
Cities
13
Industry-sponsored
7
Phase 2
8
Phase 3

Asthma clinical trials in Colorado: what to expect

Most recruiting asthma trials are for moderate-to-severe asthma that stays uncontrolled on an inhaled steroid. They test biologic injections aimed at the type of inflammation driving your asthma, new inhaler combinations, and longer-acting versions of existing drugs. Others study asthma in children, exercise and self-management programs, and ways to reduce flare-ups that lead to urgent care visits.

In Colorado, recruiting asthma studies are concentrated in Aurora, Colorado Springs, Denver and Lakewood. 13 of the 22 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who asthma trials usually look for

Trials ask for a confirmed diagnosis, a daily maintenance inhaler at a stated dose, and usually one or two flare-ups in the past year that needed oral steroids. Breathing tests at screening must fall in a range, and biologic trials pick participants by a blood eosinophil count or allergy markers measured at the site. Most adult trials exclude current smokers and people with COPD or another lung disease. Separate studies enroll children aged 6 to 11 and teenagers.

What taking part involves

Screening includes spirometry and blood work, then a run-in of a few weeks while you record symptoms and inhaler use in a diary or app. Biologic trials give an injection every two to eight weeks for six to twelve months, with breathing tests at each visit; many are placebo controlled, with your regular inhalers continued throughout and rescue inhaler always allowed. Flare-ups during the study are treated as usual. Study treatment and tests are free and visits are usually paid.

Questions worth asking the study team

Whether your current inhalers stay the same or are switched to a study inhaler; how often breathing tests are needed; the chance of placebo and whether an extension follows; and what to do during a flare-up while enrolled.

Showing 20 of 22 recruiting Asthma trials in Colorado

Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma
PHASE3 Anchorage, Alaska +4 sites NCT06307665
This trial is looking for adolescents aged 12 to 17 with asthma. Participants will compare two treatments for asthma that are used when needed to see which is more effective and safe.
Recruiting
A Study to Compare the Efficacy, Safety and Tolerability of FF/UMEC/VI With FF/VI in 12-17-year-olds With Asthma
PHASE3 Birmingham, Alabama +4 sites NCT05757102
This trial is looking for teenagers with asthma who need regular medication to manage their symptoms. Participants will receive a new treatment for 24 weeks to see how well it helps their asthma.
Recruiting
A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma
PHASE3 Phoenix, Arizona +4 sites NCT06664619
This trial is looking for people aged 12 and older who have been diagnosed with asthma for at least six months and currently use a quick-relief inhaler. However, it cannot include anyone who has had serious asthma attacks, recent respiratory infections, or other serious lung problems. If you're a current smoker or have recently smoked, you wouldn't be able to participate either.
Recruiting
A Study of Depemokimab in Participants of 6 to 11 Years of Age
PHASE3 Colorado Springs, Colorado +2 sites NCT07671001
This trial is looking for children aged 6 to 11 with asthma that has certain inflammation traits. Participants will take a drug called depemokimab and help researchers understand how it works and its safety.
Recruiting
A Study of Efficacy and Safety of Depemokimab Compared With Placebo in Adults and Adolescents With at Risk Type 2 Asthma
PHASE3 Aurora, Colorado +4 sites NCT07456033
This trial is looking for adults and adolescents with type 2 asthma who have experienced recent exacerbations. Participants will receive depemokimab along with their regular asthma treatment to see how well it works.
Recruiting
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma
PHASE2 Mobile, Alabama +4 sites NCT06977581
This trial is looking for adults with moderate-to-severe asthma that is not well controlled. Participants will receive shots of either the study medicine PF-07275315 or a placebo for 12 weeks and attend clinic visits over about 7.5 months.
Recruiting
A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma
PHASE2 Colorado Springs, Colorado +4 sites NCT07219173
This trial is looking for adults with moderate to severe asthma who have trouble controlling their symptoms. Participants will receive either the study drug, brenipatide, or a placebo over about 65 weeks.
Recruiting
ENV-294 for Moderate-to-Severe Asthma: A 12-Week Study in Adults
PHASE2 Colorado Springs, Colorado +4 sites NCT07301255
This trial is looking for adults with moderate to severe asthma. Participants will take either the study drug ENV-294 or a placebo once a day for 12 weeks while continuing their asthma treatments.
Recruiting
Anti Inflammatory Lipid Mediators in Asthma Lipid Anti-Inflammtory Mediators in Asthma
PHASE2 Aurora, Colorado NCT03762395
This trial is looking for adults aged 18 to 65 with asthma who are also obese. Participants will take a medication called CXA-10 to see if it helps reduce airway inflammation related to obesity.
Recruiting
Study to Improve Deployment Related Asthma by Using L-Citrulline Supplementation
PHASE2 Denver, Colorado NCT05259904
This trial is looking for adults aged 18 to 70 who have asthma related to military deployment. Participants will be given a supplement called L-Citrulline and monitored for changes in their asthma symptoms.
Recruiting
Individualizing Treatment for Asthma in Primary Care (Full Study)
PHASE4 Aurora, Colorado +4 sites NCT07052942
This trial is looking for people with asthma who want to try different treatments to help with their condition. Participants will compare using inhaled corticosteroids or azithromycin to see which is more effective.
Recruiting
Obesity, Metabolic Dysregulation and the Airway Epithelium in Asthmatics
NA Aurora, Colorado NCT03215836
This trial is looking for adults with asthma, obesity, and metabolic syndrome to study how these conditions affect airway health. Participants will undergo assessments related to their breathing and overall health.
Recruiting
Registry of Asthma Characterization and Recruitment 3 (RACR3)
N/A Aurora, Colorado +4 sites NCT05272241
This trial is looking for people with asthma to join a database for future studies. Participants will provide information but will not receive treatment as part of this registry.
Recruiting
Protocol CAUSE-03 / CHEETAH
N/A Aurora, Colorado +4 sites NCT06136091
This trial is looking for children and teenagers aged 6-17, some with asthma and some without. Participants will be monitored over a year while reporting on their cold symptoms and visiting the clinic at scheduled times.
Recruiting
A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-1)
PHASE3 Northridge, California +4 sites NCT07276724
This trial is looking for adults and teenagers with severe asthma that isn't controlled well by their current treatments. Participants will receive either the study drug GB-0895 or a placebo every six months for a year, with regular check-ins.
Recruiting
Randomised Clinical Trial to Investigate Efficacy and Safety of Benralizumab 30 mg SC as an add-on Therapy in Uncontrolled Eosinophilic Asthma Patients Treated With Medium-dose ICS-LABA Compared to Conventional Escalation to High-dose ICS-LABA Treatment
PHASE3 Chandler, Arizona +4 sites NCT06750289
This trial is looking for people aged 12 to 75 with eosinophilic asthma that is not well controlled. Participants will receive an additional therapy called benralizumab while continuing their current asthma medication.
Recruiting
A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma
PHASE2 Lancaster, California +4 sites NCT07323654
This trial is looking for adults aged 18 to 75 who have moderate to severe eosinophilic asthma that is not well controlled. Participants will take a medication called KT-621 to see how well it works and monitor any side effects.
Recruiting
PULmonary Stimulation for Asthma Relief
NA Denver, Colorado +2 sites NCT07709754
This trial is looking for adults aged 18 to 75 with moderate to severe asthma that is not well controlled. Participants will assess a new treatment to see if it is safe and effective.
Recruiting
Navigating Together for Equitable Asthma Management for Children in Families Who Communicate in Language Other Than English
NA Aurora, Colorado NCT06239844
This trial is looking for families with children aged 4 to 12 who have persistent asthma. Participants will receive extra help and education about managing asthma.
Recruiting
Roll-over Study for Participants Who Have Completed a Previous Clinical Study With Benralizumab (Fasenra) and Benefit From Continued Treatment
PHASE3 Aurora, Colorado +4 sites NCT07444567
This trial is looking for people who have completed a previous study with benralizumab and may benefit from continued treatment. Participants will receive benralizumab and be monitored for safety and how well it works over time.
Recruiting

Where the Asthma studies are in Colorado

  • National Jewish Health, Denver3 trials
  • Children's Hospital Colorado: Allergy Program, Aurora2 trials
  • GSK Investigational Site, Colorado Springs2 trials
  • Research Site, Denver2 trials
  • Asthma & Allergy Associates - Colorado Springs, Colorado Springs1 trial
  • Children's Hospital Colorado, Aurora1 trial

Counts are recruiting studies listing at least one site in Colorado, from ClinicalTrials.gov, refreshed every two days.

Asthma clinical trials in Colorado: common questions

How many Asthma clinical trials are recruiting in Colorado?
TrialFinder currently lists 22 recruiting Asthma clinical trials with study sites in Colorado. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Asthma clinical trials located in Colorado?
Study sites for the Asthma trials listed on this page include Colorado Springs, Aurora, Denver. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Asthma clinical trial in Colorado?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Asthma trials in Colorado also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Asthma clinical trial in Colorado?
Each study sets its own criteria based on age, Asthma diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need to stop my inhaler to join an asthma trial?
No. Trials add the study treatment to your maintenance inhaler, or replace it with a study-supplied version, and a rescue inhaler is always permitted. Any change is made by the study doctor.
What is an eosinophil count and why do trials ask about it?
It is a type of white blood cell measured in a routine blood test. Many biologic asthma drugs target the inflammation it signals, so trials set a minimum or maximum count. The site measures it at screening.
Are there asthma trials for children?
Yes. Biologics and inhalers approved for adults are studied in children aged 6 to 11 and in teenagers, with a parent consenting and attending visits. The listing states the age range.
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Asthma trials evaluate biologic therapies, inhaler formulations, allergen immunotherapy, and environmental interventions for moderate-to-severe asthma and COPD overlap.

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