CXA-10 for Obese Adult Asthmatics
Anti Inflammatory Lipid Mediators in Asthma Lipid Anti-Inflammtory Mediators in Asthma
Recruiting
Phase 2
Interventional Study
Asthma
Obesity
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 – 65
- Sex
- Any
- Trial phase
- Phase 2
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 60 (estimated)
- Sponsor
- University of Colorado, Denver · Other
Who this trial is looking for
This trial is looking for adults aged 18 to 65 with asthma who are also obese. Participants will take a medication called CXA-10 to see if it helps reduce airway inflammation related to obesity.
Are You a Good Fit for This Trial?
You may be able to join if
- I am between 18 and 65 years old.
- I have a body mass index (BMI) of 30 or higher.
- I have been diagnosed with asthma for over 6 months.
- I have been using inhaled corticosteroids, long-acting beta agonists, or similar asthma medications for at least 3 months.
You may not be able to join if
- I have had a respiratory infection in the last 4 weeks.
- I have taken oral or systemic corticosteroids in the last 4 weeks.
- I have been hospitalized for asthma in the last 6 weeks.
- I have had three or more asthma flare-ups needing treatment in the past year.
- I have visited the ER for asthma in the last 4 weeks.
- I currently smoke or quit smoking less than a year ago.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
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About This Trial
The main purpose of this Phase 2 double blind, placebo controlled crossover clinical study is to demonstrate the efficacy and safety of CXA-10 in obese adult asthmatics. Obesity induces a chronic systemic inflammatory state characterized by impaired adipokine signaling, pro-inflammatory cytokine responses, inflammatory cell activation and enhanced generation of oxidative inflammatory mediators. Th…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Adequate completion of informed consent process with written documentation. Male and female patients, 18 to 65 years old. Female subjects should be either post-menopausal or surgically sterile, or, if child-bearing potential (WOCP) should agree to use an acceptable method of …
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