Clinical Trials
for Asthma
Asthma trials evaluate biologic therapies, inhaler formulations, allergen immunotherapy, and environmental interventions for moderate-to-severe asthma and COPD overlap.
Asthma clinical trials: what to expect
Most recruiting asthma trials are for moderate-to-severe asthma that stays uncontrolled on an inhaled steroid. They test biologic injections aimed at the type of inflammation driving your asthma, new inhaler combinations, and longer-acting versions of existing drugs. Others study asthma in children, exercise and self-management programs, and ways to reduce flare-ups that lead to urgent care visits.
Who asthma trials usually look for
Trials ask for a confirmed diagnosis, a daily maintenance inhaler at a stated dose, and usually one or two flare-ups in the past year that needed oral steroids. Breathing tests at screening must fall in a range, and biologic trials pick participants by a blood eosinophil count or allergy markers measured at the site. Most adult trials exclude current smokers and people with COPD or another lung disease. Separate studies enroll children aged 6 to 11 and teenagers.
What taking part involves
Screening includes spirometry and blood work, then a run-in of a few weeks while you record symptoms and inhaler use in a diary or app. Biologic trials give an injection every two to eight weeks for six to twelve months, with breathing tests at each visit; many are placebo controlled, with your regular inhalers continued throughout and rescue inhaler always allowed. Flare-ups during the study are treated as usual. Study treatment and tests are free and visits are usually paid.
Questions worth asking the study team
Whether your current inhalers stay the same or are switched to a study inhaler; how often breathing tests are needed; the chance of placebo and whether an extension follows; and what to do during a flare-up while enrolled.
Showing 15 of 128 recruiting trials
Asthma clinical trials by state
Questions about Asthma clinical trials
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