20 Recruiting Trials
Clinical Trials
for Asthma in Massachusetts
20 clinical trials for Asthma are currently recruiting participants at study sites in Massachusetts. Study-related care is provided at no cost.
20
Recruiting trials
19
Study sites
5
Cities
10
Industry-sponsored
5
Phase 2
4
Phase 3
Asthma clinical trials in Massachusetts: what to expect
Most recruiting asthma trials are for moderate-to-severe asthma that stays uncontrolled on an inhaled steroid. They test biologic injections aimed at the type of inflammation driving your asthma, new inhaler combinations, and longer-acting versions of existing drugs. Others study asthma in children, exercise and self-management programs, and ways to reduce flare-ups that lead to urgent care visits.
In Massachusetts, recruiting asthma studies are concentrated in Boston, Worcester, Fall River and Lexington, with sites in 1 other city. 10 of the 20 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.
Who asthma trials usually look for
Trials ask for a confirmed diagnosis, a daily maintenance inhaler at a stated dose, and usually one or two flare-ups in the past year that needed oral steroids. Breathing tests at screening must fall in a range, and biologic trials pick participants by a blood eosinophil count or allergy markers measured at the site. Most adult trials exclude current smokers and people with COPD or another lung disease. Separate studies enroll children aged 6 to 11 and teenagers.
What taking part involves
Screening includes spirometry and blood work, then a run-in of a few weeks while you record symptoms and inhaler use in a diary or app. Biologic trials give an injection every two to eight weeks for six to twelve months, with breathing tests at each visit; many are placebo controlled, with your regular inhalers continued throughout and rescue inhaler always allowed. Flare-ups during the study are treated as usual. Study treatment and tests are free and visits are usually paid.
Questions worth asking the study team
Whether your current inhalers stay the same or are switched to a study inhaler; how often breathing tests are needed; the chance of placebo and whether an extension follows; and what to do during a flare-up while enrolled.
Showing 20 of 20 recruiting Asthma trials in Massachusetts
A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma
Recruiting
This trial is looking for children aged 5 to under 12 with severe asthma. Participants will receive either the treatment or a placebo for their asthma management.
Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma
Recruiting
This trial is looking for adolescents aged 12 to 17 with asthma. Participants will compare two treatments for asthma that are used when needed to see which is more effective and safe.
A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma
Recruiting
This trial is looking for people aged 12 and older who have been diagnosed with asthma for at least six months and currently use a quick-relief inhaler. However, it cannot include anyone who has had serious asthma attacks, recent respiratory infections, or other serious lung problems. If you're a current smoker or have recently smoked, you wouldn't be able to participate either.
A Phase II Study to Investigate Lung Function With 2 Different Doses of Inhaled Glycopyrronium Taken With BFF Compared to BFF in Participants of 4 to Less Than 12 Years of Age With Asthma
Recruiting
This trial is looking for children aged 4 to less than 12 who have asthma. Participants will take a medication called glycopyrronium along with another asthma treatment to see how it helps lung function.
A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma
Recruiting
This trial is looking for adults with moderate to severe asthma who have trouble controlling their symptoms. Participants will receive either the study drug, brenipatide, or a placebo over about 65 weeks.
Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids
Recruiting
This trial is looking for adults with uncontrolled asthma who are already using medium to high doses of inhaled steroids. Participants will receive injections of a medication called tozorakimab to see how well it works and whether it is safe.
ENV-294 for Moderate-to-Severe Asthma: A 12-Week Study in Adults
Recruiting
This trial is looking for adults with moderate to severe asthma. Participants will take either the study drug ENV-294 or a placebo once a day for 12 weeks while continuing their asthma treatments.
Individualizing Treatment for Asthma in Primary Care (Full Study)
Recruiting
This trial is looking for people with asthma who want to try different treatments to help with their condition. Participants will compare using inhaled corticosteroids or azithromycin to see which is more effective.
Pilot Study to Identify the Mediators and Inflammatory Cell Surface Receptors Involved in Allergic Airway Inflammation
Recruiting
This trial is looking for individuals with allergic asthma and related allergies, as well as healthy volunteers. Participants will undergo interviews and various health assessments to help researchers understand airway inflammation.
Registry of Asthma Characterization and Recruitment 3 (RACR3)
Recruiting
This trial is looking for people with asthma to join a database for future studies. Participants will provide information but will not receive treatment as part of this registry.
Protocol CAUSE-03 / CHEETAH
Recruiting
This trial is looking for children and teenagers aged 6-17, some with asthma and some without. Participants will be monitored over a year while reporting on their cold symptoms and visiting the clinic at scheduled times.
A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-2)
Recruiting
This trial is looking for adults and adolescents with severe asthma that is not well controlled by standard treatments. Participants will receive either the study drug GB-0895 or a placebo every 6 months for one year, with regular visits to monitor their health.
A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma
Recruiting
This trial is looking for adults aged 18 to 75 who have moderate to severe eosinophilic asthma that is not well controlled. Participants will take a medication called KT-621 to see how well it works and monitor any side effects.
A Study of CDX-622 in Participants With Mild to Moderate Asthma
Recruiting
This trial is looking for adults with mild to moderate asthma who want to test a new treatment. Participants will take the treatment and follow up on their asthma symptoms and health for safety and effectiveness.
Asthma Link Effectiveness Trial
Recruiting
This trial is looking for children aged 5-14 who have asthma that is hard to control. Participants will either take part in a supervised asthma therapy program or use an educational workbook to help manage their symptoms.
Comparative-effectiveness of a Healthy Lifestyle and Asthma Management Program, In-person vs. ONline
Recruiting
This trial is looking for children aged 4 to 17 who are overweight and have asthma. Participants will take part in a program that teaches healthy living, either in-person or online.
Home Hospital for Suddenly Ill Adults
Recruiting
This trial is looking for adults who suddenly become ill and may need hospital care at home instead of a traditional hospital. Participants will receive treatment in their own home with support from a caregiver.
Social Needs Screening and Chronic Diseases Study (WE CARE)
Recruiting
This trial is looking for adults and children with certain chronic diseases who receive care at specific clinics. Participants will be involved in screening for social health needs and how it may help improve their health outcomes.
Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU
Recruiting
This trial is looking for adults with lung issues who might benefit from a new portable imaging technology. Participants will have a few sets of special chest images taken to help doctors make better diagnoses.
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
Recruiting
This trial is looking for children and young adults who are 21 years old or younger and are currently taking certain medications, or who have had a recent COVID-19 infection. They cannot be pregnant or have had certain recent medical procedures like dialysis, organ transplants, or other serious treatments. If you think your child might fit this description, it could be worth considering.
Where the Asthma studies are in Massachusetts
Research sites running the most studies
- Brigham and Women's Hospital, Boston4 trials
- Research Site, Boston3 trials
- Boston Children's Hospital: Department of Immunology, Boston2 trials
- Massachusetts General Hospital, Boston2 trials
- Boston Children's Hospital, Boston1 trial
- Boston University School of Medicine: Pulmonary Center, Boston1 trial
By city
Counts are recruiting studies listing at least one site in Massachusetts, from ClinicalTrials.gov, refreshed every two days.
Asthma clinical trials in Massachusetts: common questions
How many Asthma clinical trials are recruiting in Massachusetts?
TrialFinder currently lists 20 recruiting Asthma clinical trials with study sites in Massachusetts. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Asthma clinical trials located in Massachusetts?
Study sites for the Asthma trials listed on this page include Worcester, Boston. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Asthma clinical trial in Massachusetts?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Asthma trials in Massachusetts also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Asthma clinical trial in Massachusetts?
Each study sets its own criteria based on age, Asthma diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need to stop my inhaler to join an asthma trial?
No. Trials add the study treatment to your maintenance inhaler, or replace it with a study-supplied version, and a rescue inhaler is always permitted. Any change is made by the study doctor.
What is an eosinophil count and why do trials ask about it?
It is a type of white blood cell measured in a routine blood test. Many biologic asthma drugs target the inflammation it signals, so trials set a minimum or maximum count. The site measures it at screening.
Are there asthma trials for children?
Yes. Biologics and inhalers approved for adults are studied in children aged 6 to 11 and in teenagers, with a parent consenting and attending visits. The listing states the age range.
Asthma Trials in Other States
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Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
All guides →
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
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About Asthma Trials
Asthma trials evaluate biologic therapies, inhaler formulations, allergen immunotherapy, and environmental interventions for moderate-to-severe asthma and COPD overlap.
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