Asthma Trials / Trials in Missouri
17 Recruiting Trials

Clinical Trials
for Asthma in Missouri

17 clinical trials for Asthma are currently recruiting participants at study sites in Missouri. Study-related care is provided at no cost.

17
Recruiting trials
24
Study sites
3
Cities
13
Industry-sponsored
7
Phase 2
6
Phase 3

Asthma clinical trials in Missouri: what to expect

Most recruiting asthma trials are for moderate-to-severe asthma that stays uncontrolled on an inhaled steroid. They test biologic injections aimed at the type of inflammation driving your asthma, new inhaler combinations, and longer-acting versions of existing drugs. Others study asthma in children, exercise and self-management programs, and ways to reduce flare-ups that lead to urgent care visits.

In Missouri, recruiting asthma studies are concentrated in St Louis, Columbia and Kansas City. 13 of the 17 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who asthma trials usually look for

Trials ask for a confirmed diagnosis, a daily maintenance inhaler at a stated dose, and usually one or two flare-ups in the past year that needed oral steroids. Breathing tests at screening must fall in a range, and biologic trials pick participants by a blood eosinophil count or allergy markers measured at the site. Most adult trials exclude current smokers and people with COPD or another lung disease. Separate studies enroll children aged 6 to 11 and teenagers.

What taking part involves

Screening includes spirometry and blood work, then a run-in of a few weeks while you record symptoms and inhaler use in a diary or app. Biologic trials give an injection every two to eight weeks for six to twelve months, with breathing tests at each visit; many are placebo controlled, with your regular inhalers continued throughout and rescue inhaler always allowed. Flare-ups during the study are treated as usual. Study treatment and tests are free and visits are usually paid.

Questions worth asking the study team

Whether your current inhalers stay the same or are switched to a study inhaler; how often breathing tests are needed; the chance of placebo and whether an extension follows; and what to do during a flare-up while enrolled.

Showing 17 of 17 recruiting Asthma trials in Missouri

Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma
PHASE3 Anchorage, Alaska +4 sites NCT06307665
This trial is looking for adolescents aged 12 to 17 with asthma. Participants will compare two treatments for asthma that are used when needed to see which is more effective and safe.
Recruiting
A Study to Compare the Efficacy, Safety and Tolerability of FF/UMEC/VI With FF/VI in 12-17-year-olds With Asthma
PHASE3 Birmingham, Alabama +4 sites NCT05757102
This trial is looking for teenagers with asthma who need regular medication to manage their symptoms. Participants will receive a new treatment for 24 weeks to see how well it helps their asthma.
Recruiting
A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma
PHASE3 Phoenix, Arizona +4 sites NCT06664619
This trial is looking for people aged 12 and older who have been diagnosed with asthma for at least six months and currently use a quick-relief inhaler. However, it cannot include anyone who has had serious asthma attacks, recent respiratory infections, or other serious lung problems. If you're a current smoker or have recently smoked, you wouldn't be able to participate either.
Recruiting
Depemokimab Asthma Imaging and Bronchoscopy Sub-Study
PHASE3 St Louis, Missouri +4 sites NCT06979323
This trial is looking for adults with asthma that has been diagnosed for at least 2 years. Participants will take a medication called depemokimab and help researchers understand its effects on lung health.
Recruiting
Study to Evaluate the Safety, Pharmacology and Efficacy of WIN378 in Adults With Moderate or Severe Asthma
PHASE2 Los Angeles, California +4 sites NCT07120503
Recruiting
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma
PHASE2 Mobile, Alabama +4 sites NCT06977581
This trial is looking for adults with moderate-to-severe asthma that is not well controlled. Participants will receive shots of either the study medicine PF-07275315 or a placebo for 12 weeks and attend clinic visits over about 7.5 months.
Recruiting
A Phase II Study to Investigate Lung Function With 2 Different Doses of Inhaled Glycopyrronium Taken With BFF Compared to BFF in Participants of 4 to Less Than 12 Years of Age With Asthma
PHASE2 Bakersfield, California +4 sites NCT07525375
This trial is looking for children aged 4 to less than 12 who have asthma. Participants will take a medication called glycopyrronium along with another asthma treatment to see how it helps lung function.
Recruiting
Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids
PHASE2 Bakersfield, California +4 sites NCT06932263
This trial is looking for adults with uncontrolled asthma who are already using medium to high doses of inhaled steroids. Participants will receive injections of a medication called tozorakimab to see how well it works and whether it is safe.
Recruiting
ENV-294 for Moderate-to-Severe Asthma: A 12-Week Study in Adults
PHASE2 Birmingham, Alabama +4 sites NCT07301255
This trial is looking for adults with moderate to severe asthma. Participants will take either the study drug ENV-294 or a placebo once a day for 12 weeks while continuing their asthma treatments.
Recruiting
Individualizing Treatment for Asthma in Primary Care (Full Study)
PHASE4 Aurora, Colorado +4 sites NCT07052942
This trial is looking for people with asthma who want to try different treatments to help with their condition. Participants will compare using inhaled corticosteroids or azithromycin to see which is more effective.
Recruiting
A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-2)
PHASE3 Bakersfield, California +4 sites NCT07359846
This trial is looking for adults and adolescents with severe asthma that is not well controlled by standard treatments. Participants will receive either the study drug GB-0895 or a placebo every 6 months for one year, with regular visits to monitor their health.
Recruiting
Rademikibart IV for Acute Asthma and COPD Exacerbation
PHASE2 St Louis, Missouri +2 sites NCT07705737
This trial is looking for adults with asthma or COPD who are currently experiencing a serious flare-up. Participants will receive an intravenous treatment called rademikibart in addition to their usual care.
Recruiting
A Clinical Study to Evaluate the Efficacy and Safety of Frevecitinib (KN-002) in Patients With Severe Asthma
PHASE2 Lancaster, California +4 sites NCT07532265
This trial is looking for people with severe asthma who are not managing their symptoms with current treatments. Participants will take Frevecitinib for 12 weeks and will need to provide consent and follow specific guidelines throughout the study.
Recruiting
CHEST: A Collaboration With Community HEalth Centers to Implement SmarT for Asthma
PHASE4 St Louis, Missouri +4 sites NCT07241117
This trial is looking for patients with moderate to severe asthma who receive care at specific health clinics. Taking part involves receiving care from trained clinicians who will provide new asthma treatment options and support.
Recruiting
Resources and Education for Addressing Chronic Health (REACH)
NA St Louis, Missouri NCT07819747
This trial is looking for children with asthma and their parents to help improve communication and care for asthma management at school and home. Participants will work with school nurses and healthcare providers to better support children with asthma.
Recruiting
A Study to Compare Safety of 4 Weeks Exposure to Propellants Hydrofluoroalkane 1,1-difluoroethane (HFA-152a) and HFA-1,1,1,2-tetrafluoroethane (134a)
PHASE3 Aventura, Florida +4 sites NCT07645248
This trial is looking for adults with asthma who have been stable for a while and are currently using certain asthma medications. Participants will use a specific inhaler containing one of two propellants for 4 weeks to compare safety.
Recruiting
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
N/A Phoenix, Arizona +4 sites NCT04278404
This trial is looking for children and young adults who are 21 years old or younger and are currently taking certain medications, or who have had a recent COVID-19 infection. They cannot be pregnant or have had certain recent medical procedures like dialysis, organ transplants, or other serious treatments. If you think your child might fit this description, it could be worth considering.
Recruiting
See all 17 Asthma trials in Missouri

Where the Asthma studies are in Missouri

Research sites running the most studies
  • GSK Investigational Site, Columbia2 trials
  • Research Site, St Louis2 trials
  • Affinia healthcare, 1717 Biddle Street, St Louis1 trial
  • Affinia healthcare, 2220 Lemp Ave, St Louis1 trial
  • Affinia healthcare, 3396 Pershall Road,, St Louis1 trial
  • Affinia healthcare, 4414 North Florissant Avenue, St Louis1 trial
By city

Counts are recruiting studies listing at least one site in Missouri, from ClinicalTrials.gov, refreshed every two days.

Asthma clinical trials in Missouri: common questions

How many Asthma clinical trials are recruiting in Missouri?
TrialFinder currently lists 17 recruiting Asthma clinical trials with study sites in Missouri. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Asthma clinical trials located in Missouri?
Study sites for the Asthma trials listed on this page include St Louis. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Asthma clinical trial in Missouri?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Asthma trials in Missouri also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Asthma clinical trial in Missouri?
Each study sets its own criteria based on age, Asthma diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need to stop my inhaler to join an asthma trial?
No. Trials add the study treatment to your maintenance inhaler, or replace it with a study-supplied version, and a rescue inhaler is always permitted. Any change is made by the study doctor.
What is an eosinophil count and why do trials ask about it?
It is a type of white blood cell measured in a routine blood test. Many biologic asthma drugs target the inflammation it signals, so trials set a minimum or maximum count. The site measures it at screening.
Are there asthma trials for children?
Yes. Biologics and inhalers approved for adults are studied in children aged 6 to 11 and in teenagers, with a parent consenting and attending visits. The listing states the age range.
Asthma Trials in Other States
Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware District of Columbia Florida Georgia Hawaii Idaho Illinois Indiana Iowa Kansas Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Mississippi Montana Nebraska Nevada New Hampshire New Jersey New Mexico New York North Carolina North Dakota Ohio Oklahoma Oregon Pennsylvania Rhode Island South Carolina South Dakota Tennessee Texas Utah Vermont Virginia Washington West Virginia Wisconsin Wyoming
Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
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About Asthma Trials

Asthma trials evaluate biologic therapies, inhaler formulations, allergen immunotherapy, and environmental interventions for moderate-to-severe asthma and COPD overlap.

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