Asthma Trials / Trials in Illinois
15 Recruiting Trials

Clinical Trials
for Asthma in Illinois

15 clinical trials for Asthma are currently recruiting participants at study sites in Illinois. Study-related care is provided at no cost.

15
Recruiting trials
18
Study sites
7
Cities
9
Industry-sponsored
5
Phase 2
4
Phase 3

Asthma clinical trials in Illinois: what to expect

Most recruiting asthma trials are for moderate-to-severe asthma that stays uncontrolled on an inhaled steroid. They test biologic injections aimed at the type of inflammation driving your asthma, new inhaler combinations, and longer-acting versions of existing drugs. Others study asthma in children, exercise and self-management programs, and ways to reduce flare-ups that lead to urgent care visits.

In Illinois, recruiting asthma studies are concentrated in Chicago, Normal, Westchester and Champaign, with sites in 3 other cities. 9 of the 15 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who asthma trials usually look for

Trials ask for a confirmed diagnosis, a daily maintenance inhaler at a stated dose, and usually one or two flare-ups in the past year that needed oral steroids. Breathing tests at screening must fall in a range, and biologic trials pick participants by a blood eosinophil count or allergy markers measured at the site. Most adult trials exclude current smokers and people with COPD or another lung disease. Separate studies enroll children aged 6 to 11 and teenagers.

What taking part involves

Screening includes spirometry and blood work, then a run-in of a few weeks while you record symptoms and inhaler use in a diary or app. Biologic trials give an injection every two to eight weeks for six to twelve months, with breathing tests at each visit; many are placebo controlled, with your regular inhalers continued throughout and rescue inhaler always allowed. Flare-ups during the study are treated as usual. Study treatment and tests are free and visits are usually paid.

Questions worth asking the study team

Whether your current inhalers stay the same or are switched to a study inhaler; how often breathing tests are needed; the chance of placebo and whether an extension follows; and what to do during a flare-up while enrolled.

Showing 15 of 15 recruiting Asthma trials in Illinois

Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma
PHASE3 Anchorage, Alaska +4 sites NCT06307665
This trial is looking for adolescents aged 12 to 17 with asthma. Participants will compare two treatments for asthma that are used when needed to see which is more effective and safe.
Recruiting
A Study to Compare the Efficacy, Safety and Tolerability of FF/UMEC/VI With FF/VI in 12-17-year-olds With Asthma
PHASE3 Birmingham, Alabama +4 sites NCT05757102
This trial is looking for teenagers with asthma who need regular medication to manage their symptoms. Participants will receive a new treatment for 24 weeks to see how well it helps their asthma.
Recruiting
A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma
PHASE3 Phoenix, Arizona +4 sites NCT06664619
This trial is looking for people aged 12 and older who have been diagnosed with asthma for at least six months and currently use a quick-relief inhaler. However, it cannot include anyone who has had serious asthma attacks, recent respiratory infections, or other serious lung problems. If you're a current smoker or have recently smoked, you wouldn't be able to participate either.
Recruiting
A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma
PHASE2 Tempe, Arizona +4 sites NCT07219173
This trial is looking for adults with moderate to severe asthma who have trouble controlling their symptoms. Participants will receive either the study drug, brenipatide, or a placebo over about 65 weeks.
Recruiting
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma
PHASE2 Mobile, Alabama +4 sites NCT06977581
This trial is looking for adults with moderate-to-severe asthma that is not well controlled. Participants will receive shots of either the study medicine PF-07275315 or a placebo for 12 weeks and attend clinic visits over about 7.5 months.
Recruiting
ENV-294 for Moderate-to-Severe Asthma: A 12-Week Study in Adults
PHASE2 Birmingham, Alabama +4 sites NCT07301255
This trial is looking for adults with moderate to severe asthma. Participants will take either the study drug ENV-294 or a placebo once a day for 12 weeks while continuing their asthma treatments.
Recruiting
A Study Evaluating Disease Characteristics and Outcomes in Participants With Asthma in Routine Clinical Practice
N/A Bessemer, Alabama +4 sites NCT07556159
This trial is looking for people with asthma to understand their condition better. Participants will share details about their asthma severity, treatments, and health-related quality of life.
Recruiting
Registry of Asthma Characterization and Recruitment 3 (RACR3)
N/A Chicago, Illinois +4 sites NCT05272241
This trial is looking for people with asthma to join a database for future studies. Participants will provide information but will not receive treatment as part of this registry.
Recruiting
Protocol CAUSE-03 / CHEETAH
N/A Chicago, Illinois +4 sites NCT06136091
This trial is looking for children and teenagers aged 6-17, some with asthma and some without. Participants will be monitored over a year while reporting on their cold symptoms and visiting the clinic at scheduled times.
Recruiting
A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-1)
PHASE3 Northridge, California +4 sites NCT07276724
This trial is looking for adults and teenagers with severe asthma that isn't controlled well by their current treatments. Participants will receive either the study drug GB-0895 or a placebo every six months for a year, with regular check-ins.
Recruiting
A Clinical Study to Evaluate the Efficacy and Safety of Frevecitinib (KN-002) in Patients With Severe Asthma
PHASE2 Lancaster, California +4 sites NCT07532265
This trial is looking for people with severe asthma who are not managing their symptoms with current treatments. Participants will take Frevecitinib for 12 weeks and will need to provide consent and follow specific guidelines throughout the study.
Recruiting
Technology-Enhanced Asthma Care in Children at Clinic and Home Study
NA Chicago, Illinois NCT06820593
This trial is looking for children ages 4 to 17 with uncontrolled asthma and their caregivers. Participants will use a mobile app and sensors to help manage asthma better with some additional support.
Recruiting
Soy Isoflavones For Inner City Infants At Risk For Asthma (SIRA) Study
PHASE2 Chicago, Illinois +1 sites NCT05667701
This trial is looking for infants under 12 months old who are at risk for asthma. Participants will take a soy treatment or a placebo for seven months and will have several visits to check on their health.
Recruiting
Post-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School Age
N/A Chicago, Illinois NCT05336890
This trial is looking for children who were born very premature and are under 7 years old. It aims to find out if breathing patterns from their time in the NICU relate to issues like asthma and sleep problems as they grow up.
Recruiting
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
N/A Phoenix, Arizona +4 sites NCT04278404
This trial is looking for children and young adults who are 21 years old or younger and are currently taking certain medications, or who have had a recent COVID-19 infection. They cannot be pregnant or have had certain recent medical procedures like dialysis, organ transplants, or other serious treatments. If you think your child might fit this description, it could be worth considering.
Recruiting
See all 15 Asthma trials in Illinois

Where the Asthma studies are in Illinois

Research sites running the most studies
  • Ann & Robert H. Lurie Children's Hospital of Chicago: Division of Allergy and Immunology, Chicago2 trials
  • Ann & Robert H Lurie Children's Hospital of Chicago, Chicago1 trial
  • Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago1 trial
  • Ann and Robert H Lurie Childrens Hospital of Chicago, Chicago1 trial
  • Ann and Robert H. Lurie Childrens Hospital of Chicago, Chicago1 trial
  • Axis Clinical Trials - Westchester, Westchester1 trial
By city

Counts are recruiting studies listing at least one site in Illinois, from ClinicalTrials.gov, refreshed every two days.

Asthma clinical trials in Illinois: common questions

How many Asthma clinical trials are recruiting in Illinois?
TrialFinder currently lists 15 recruiting Asthma clinical trials with study sites in Illinois. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Asthma clinical trials located in Illinois?
Study sites for the Asthma trials listed on this page include Chicago. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Asthma clinical trial in Illinois?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Asthma trials in Illinois also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Asthma clinical trial in Illinois?
Each study sets its own criteria based on age, Asthma diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need to stop my inhaler to join an asthma trial?
No. Trials add the study treatment to your maintenance inhaler, or replace it with a study-supplied version, and a rescue inhaler is always permitted. Any change is made by the study doctor.
What is an eosinophil count and why do trials ask about it?
It is a type of white blood cell measured in a routine blood test. Many biologic asthma drugs target the inflammation it signals, so trials set a minimum or maximum count. The site measures it at screening.
Are there asthma trials for children?
Yes. Biologics and inhalers approved for adults are studied in children aged 6 to 11 and in teenagers, with a parent consenting and attending visits. The listing states the age range.
Asthma Trials in Other States
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Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
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About Asthma Trials

Asthma trials evaluate biologic therapies, inhaler formulations, allergen immunotherapy, and environmental interventions for moderate-to-severe asthma and COPD overlap.

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