21 Recruiting Trials
Clinical Trials
for Asthma in Pennsylvania
21 clinical trials for Asthma are currently recruiting participants at study sites in Pennsylvania. Study-related care is provided at no cost.
21
Recruiting trials
24
Study sites
7
Cities
14
Industry-sponsored
6
Phase 2
6
Phase 3
Asthma clinical trials in Pennsylvania: what to expect
Most recruiting asthma trials are for moderate-to-severe asthma that stays uncontrolled on an inhaled steroid. They test biologic injections aimed at the type of inflammation driving your asthma, new inhaler combinations, and longer-acting versions of existing drugs. Others study asthma in children, exercise and self-management programs, and ways to reduce flare-ups that lead to urgent care visits.
In Pennsylvania, recruiting asthma studies are concentrated in Pittsburgh, Philadelphia, DuBois and Hershey, with sites in 3 other cities. 14 of the 21 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.
Who asthma trials usually look for
Trials ask for a confirmed diagnosis, a daily maintenance inhaler at a stated dose, and usually one or two flare-ups in the past year that needed oral steroids. Breathing tests at screening must fall in a range, and biologic trials pick participants by a blood eosinophil count or allergy markers measured at the site. Most adult trials exclude current smokers and people with COPD or another lung disease. Separate studies enroll children aged 6 to 11 and teenagers.
What taking part involves
Screening includes spirometry and blood work, then a run-in of a few weeks while you record symptoms and inhaler use in a diary or app. Biologic trials give an injection every two to eight weeks for six to twelve months, with breathing tests at each visit; many are placebo controlled, with your regular inhalers continued throughout and rescue inhaler always allowed. Flare-ups during the study are treated as usual. Study treatment and tests are free and visits are usually paid.
Questions worth asking the study team
Whether your current inhalers stay the same or are switched to a study inhaler; how often breathing tests are needed; the chance of placebo and whether an extension follows; and what to do during a flare-up while enrolled.
Showing 20 of 21 recruiting Asthma trials in Pennsylvania
Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma
Recruiting
This trial is looking for adolescents aged 12 to 17 with asthma. Participants will compare two treatments for asthma that are used when needed to see which is more effective and safe.
A Study to Learn About the Study Medicine Called Tilrekimig ( PF-07275315) in People With Severe Asthma
Recruiting
This trial is looking for people with severe asthma who have had recent asthma attacks. Participants will receive shots of either the study medicine, tilrekimig, or a placebo every 4 weeks to see how they respond.
A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma
Recruiting
This trial is looking for people aged 12 and older who have been diagnosed with asthma for at least six months and currently use a quick-relief inhaler. However, it cannot include anyone who has had serious asthma attacks, recent respiratory infections, or other serious lung problems. If you're a current smoker or have recently smoked, you wouldn't be able to participate either.
A Study of Efficacy and Safety of Depemokimab Compared With Placebo in Adults and Adolescents With at Risk Type 2 Asthma
Recruiting
This trial is looking for adults and adolescents with type 2 asthma who have experienced recent exacerbations. Participants will receive depemokimab along with their regular asthma treatment to see how well it works.
Depemokimab Asthma Imaging and Bronchoscopy Sub-Study
Recruiting
This trial is looking for adults with asthma that has been diagnosed for at least 2 years. Participants will take a medication called depemokimab and help researchers understand its effects on lung health.
A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma
Recruiting
This trial is looking for adults with moderate to severe asthma who have trouble controlling their symptoms. Participants will receive either the study drug, brenipatide, or a placebo over about 65 weeks.
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma
Recruiting
This trial is looking for adults with moderate-to-severe asthma that is not well controlled. Participants will receive shots of either the study medicine PF-07275315 or a placebo for 12 weeks and attend clinic visits over about 7.5 months.
Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids
Recruiting
This trial is looking for adults with uncontrolled asthma who are already using medium to high doses of inhaled steroids. Participants will receive injections of a medication called tozorakimab to see how well it works and whether it is safe.
Measuring the Effect of Dupilumab Treatment on Mucociliary Clearance (MCC) in Subjects With Moderate to Severe Asthma
Recruiting
This trial is looking for adults with moderate to severe asthma to see how a treatment called dupilumab affects a specific way the body clears mucus. Participants will receive either the treatment or a placebo to compare results.
A Study Evaluating Disease Characteristics and Outcomes in Participants With Asthma in Routine Clinical Practice
Recruiting
This trial is looking for people with asthma to understand their condition better. Participants will share details about their asthma severity, treatments, and health-related quality of life.
Randomised Clinical Trial to Investigate Efficacy and Safety of Benralizumab 30 mg SC as an add-on Therapy in Uncontrolled Eosinophilic Asthma Patients Treated With Medium-dose ICS-LABA Compared to Conventional Escalation to High-dose ICS-LABA Treatment
Recruiting
This trial is looking for people aged 12 to 75 with eosinophilic asthma that is not well controlled. Participants will receive an additional therapy called benralizumab while continuing their current asthma medication.
A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma
Recruiting
This trial is looking for adults aged 18 to 75 who have moderate to severe eosinophilic asthma that is not well controlled. Participants will take a medication called KT-621 to see how well it works and monitor any side effects.
A Clinical Study to Evaluate the Efficacy and Safety of Frevecitinib (KN-002) in Patients With Severe Asthma
Recruiting
This trial is looking for people with severe asthma who are not managing their symptoms with current treatments. Participants will take Frevecitinib for 12 weeks and will need to provide consent and follow specific guidelines throughout the study.
A Study of CDX-622 in Participants With Mild to Moderate Asthma
Recruiting
This trial is looking for adults with mild to moderate asthma who want to test a new treatment. Participants will take the treatment and follow up on their asthma symptoms and health for safety and effectiveness.
Bilevel Positive Airway Pressure (BPAP) for Severe Asthma
Recruiting
This trial is looking for children aged 5 to 17 who are having severe asthma attacks. If you join, you will receive standard asthma treatment and may also receive a device called BPAP to help with your breathing in the emergency room.
Pollution Intervention to Impact Kids Asthma Study
Recruiting
This trial is looking for children ages 8 to 17 with asthma who live in Allegheny County, PA. Participants will receive education about outdoor air pollution, an asthma action plan, and have periodic check-ins for a year.
Acoustic Waveform Respiratory Evaluation
Recruiting
This trial is looking for people aged 8 to 70 to participate in a study using smartphone speakers and microphones to check airway health. Participants will perform some breathing tests to help diagnose and monitor respiratory diseases like asthma and COPD.
Recruiting
SMART Implementation-Effectiveness Trial 2
Recruiting
This trial is looking for children aged 5 to 18 with asthma who are receiving care at a specific clinic. Participants will help test new ways to improve asthma treatment using a method called SMART.
Where the Asthma studies are in Pennsylvania
Research sites running the most studies
- Children's Hospital of Philadelphia, Philadelphia3 trials
- Allergy and Clinical Immunology Associates, Pittsburgh2 trials
- GSK Investigational Site, DuBois2 trials
- Research Site, DuBois2 trials
- Allergy and Clinical Immunology Associates - Site Number: 840127, Pittsburgh1 trial
- Clinical Research Associates of Central PA, LLC, DuBois1 trial
By city
Counts are recruiting studies listing at least one site in Pennsylvania, from ClinicalTrials.gov, refreshed every two days.
Asthma clinical trials in Pennsylvania: common questions
How many Asthma clinical trials are recruiting in Pennsylvania?
TrialFinder currently lists 21 recruiting Asthma clinical trials with study sites in Pennsylvania. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Asthma clinical trials located in Pennsylvania?
Study sites for the Asthma trials listed on this page include Pittsburgh, Philadelphia. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Asthma clinical trial in Pennsylvania?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Asthma trials in Pennsylvania also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Asthma clinical trial in Pennsylvania?
Each study sets its own criteria based on age, Asthma diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need to stop my inhaler to join an asthma trial?
No. Trials add the study treatment to your maintenance inhaler, or replace it with a study-supplied version, and a rescue inhaler is always permitted. Any change is made by the study doctor.
What is an eosinophil count and why do trials ask about it?
It is a type of white blood cell measured in a routine blood test. Many biologic asthma drugs target the inflammation it signals, so trials set a minimum or maximum count. The site measures it at screening.
Are there asthma trials for children?
Yes. Biologics and inhalers approved for adults are studied in children aged 6 to 11 and in teenagers, with a parent consenting and attending visits. The listing states the age range.
Asthma Trials in Other States
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Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
All guides →
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
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About Asthma Trials
Asthma trials evaluate biologic therapies, inhaler formulations, allergen immunotherapy, and environmental interventions for moderate-to-severe asthma and COPD overlap.
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