No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
8 – 17
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
351 (estimated)
Sponsor
University of Pittsburgh · Other
Who this trial is looking for
This trial is looking for children ages 8 to 17 with asthma who live in Allegheny County, PA. Participants will receive education about outdoor air pollution, an asthma action plan, and have periodic check-ins for a year.
Are You a Good Fit for This Trial?
You may be able to join if
I have been diagnosed with persistent or intermittent asthma.
I had at least one severe asthma attack in the past year.
I am between 8 and 17 years old.
I live in Allegheny County, PA.
I can access a smartphone or the internet.
I have seen a healthcare provider for asthma in the past year.
Only one participant is allowed from my household.
You may not be able to join if
I have another active chronic respiratory disease.
I have a neuromuscular disorder.
I have a chronic condition that limits my movement.
I have cyanotic heart disease.
I plan to move from Allegheny County, PA in the next year.
I have used corticosteroids in the last 4 weeks.
I am currently taking part in another asthma trial.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The goal of this clinical trial is to learn if adding Air Quality Index (AQI) information to asthma action plans works to improve asthma outcomes in children. It will also learn about children with asthma who report being more sensitive to outdoor air pollution. The main questions it aims to answer are:
* Does adding either information about the EPA-AQI or commercial AQI improve asthma outcomes o…
The goal of this clinical trial is to learn if adding Air Quality Index (AQI) information to asthma action plans works to improve asthma outcomes in children. It will also learn about children with asthma who report being more sensitive to outdoor air pollution. The main questions it aims to answer are:
* Does adding either information about the EPA-AQI or commercial AQI improve asthma outcomes over time?
* Are there changes in nasal gene expression in children with asthma who report they are more sensitive to outdoor air pollution?
Researchers will compare EPA-AQI and the commercial-AQI groups to a control group to either AQI works to improve asthma.
Participants will:
* Receive standardized outdoor air pollution education and an asthma action plan
* Provide nose and blood specimens
* Have visits every 4 weeks for 48 weeks, 10 will be conducted by telephone calls and 3 visits will be in person.
Trial Locations
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City
State
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Status
Eligibility Criteria
Inclusion Criteria:
* A healthcare provider diagnosis of persistent asthma (Steps 2-5 as defined by US guidelines) or intermittent asthma (Step 1) + at least one severe asthma exacerbation (defined by American Thoracic Society (ATS)/European Respiratory Society (ERS) criteria as requiring at least …
Inclusion Criteria:
* A healthcare provider diagnosis of persistent asthma (Steps 2-5 as defined by US guidelines) or intermittent asthma (Step 1) + at least one severe asthma exacerbation (defined by American Thoracic Society (ATS)/European Respiratory Society (ERS) criteria as requiring at least 3 days of systemic steroids or an Emergency Department/Urgent Care visit requiring systemic steroids) in the prior 12 months
* Home access to a smartphone or internet
* Primary residence in Allegheny County, PA
* One participant per household
* Age 8 -17 years
* Healthcare provider evaluation for asthma in the prior year
Exclusion Criteria:
* Diagnosis of other active chronic respiratory diseases (e.g., cystic fibrosis, bronchopulmonary dysplasia, etc.)
* Neuromuscular disorder
* Chronic disorder limiting independent ambulation (e.g., spastic quadriplegia, etc.)
* Cyanotic heart disease
* Plans to relocate from Allegheny County, PA in the next year (12 months)
* Use of intranasal or oral/intramuscular/intravenous corticosteroids 4 weeks prior to randomization
* Current participation in another asthma intervention trial
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