Asthma Trials / Trials in Tennessee
8 Recruiting Trials

Clinical Trials
for Asthma in Tennessee

8 clinical trials for Asthma are currently recruiting participants at study sites in Tennessee. Study-related care is provided at no cost.

8
Recruiting trials
8
Study sites
5
Cities
6
Industry-sponsored
4
Phase 2
1
Phase 3

Asthma clinical trials in Tennessee: what to expect

Most recruiting asthma trials are for moderate-to-severe asthma that stays uncontrolled on an inhaled steroid. They test biologic injections aimed at the type of inflammation driving your asthma, new inhaler combinations, and longer-acting versions of existing drugs. Others study asthma in children, exercise and self-management programs, and ways to reduce flare-ups that lead to urgent care visits.

In Tennessee, recruiting asthma studies are concentrated in Nashville, Chattanooga, Hendersonville and Knoxville, with sites in 1 other city. 6 of the 8 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who asthma trials usually look for

Trials ask for a confirmed diagnosis, a daily maintenance inhaler at a stated dose, and usually one or two flare-ups in the past year that needed oral steroids. Breathing tests at screening must fall in a range, and biologic trials pick participants by a blood eosinophil count or allergy markers measured at the site. Most adult trials exclude current smokers and people with COPD or another lung disease. Separate studies enroll children aged 6 to 11 and teenagers.

What taking part involves

Screening includes spirometry and blood work, then a run-in of a few weeks while you record symptoms and inhaler use in a diary or app. Biologic trials give an injection every two to eight weeks for six to twelve months, with breathing tests at each visit; many are placebo controlled, with your regular inhalers continued throughout and rescue inhaler always allowed. Flare-ups during the study are treated as usual. Study treatment and tests are free and visits are usually paid.

Questions worth asking the study team

Whether your current inhalers stay the same or are switched to a study inhaler; how often breathing tests are needed; the chance of placebo and whether an extension follows; and what to do during a flare-up while enrolled.

Showing 8 of 8 recruiting Asthma trials in Tennessee

Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma
PHASE3 Anchorage, Alaska +4 sites NCT06307665
This trial is looking for adolescents aged 12 to 17 with asthma. Participants will compare two treatments for asthma that are used when needed to see which is more effective and safe.
Recruiting
A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma
PHASE2 Tempe, Arizona +4 sites NCT07219173
This trial is looking for adults with moderate to severe asthma who have trouble controlling their symptoms. Participants will receive either the study drug, brenipatide, or a placebo over about 65 weeks.
Recruiting
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma
PHASE2 Mobile, Alabama +4 sites NCT06977581
This trial is looking for adults with moderate-to-severe asthma that is not well controlled. Participants will receive shots of either the study medicine PF-07275315 or a placebo for 12 weeks and attend clinic visits over about 7.5 months.
Recruiting
Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids
PHASE2 Bakersfield, California +4 sites NCT06932263
This trial is looking for adults with uncontrolled asthma who are already using medium to high doses of inhaled steroids. Participants will receive injections of a medication called tozorakimab to see how well it works and whether it is safe.
Recruiting
A Study Evaluating Disease Characteristics and Outcomes in Participants With Asthma in Routine Clinical Practice
N/A Bessemer, Alabama +4 sites NCT07556159
This trial is looking for people with asthma to understand their condition better. Participants will share details about their asthma severity, treatments, and health-related quality of life.
Recruiting
A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma
PHASE2 Lancaster, California +4 sites NCT07323654
This trial is looking for adults aged 18 to 75 who have moderate to severe eosinophilic asthma that is not well controlled. Participants will take a medication called KT-621 to see how well it works and monitor any side effects.
Recruiting
Reducing Overuse of Antibiotics With Decision Support
NA Nashville, Tennessee +2 sites NCT06788093
This trial is looking for children who visit the emergency department with symptoms of lower respiratory tract infections (like cough or shortness of breath). Participating involves having their health records reviewed to see if antibiotics are needed.
Recruiting
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
N/A Phoenix, Arizona +4 sites NCT04278404
This trial is looking for children and young adults who are 21 years old or younger and are currently taking certain medications, or who have had a recent COVID-19 infection. They cannot be pregnant or have had certain recent medical procedures like dialysis, organ transplants, or other serious treatments. If you think your child might fit this description, it could be worth considering.
Recruiting
See all 8 Asthma trials in Tennessee

Where the Asthma studies are in Tennessee

Research sites running the most studies
  • Allergy Associates, PA dba Allergy, Asthma and Sinus Center - Site Number: 840144, Tennessee City1 trial
  • Kymera Investigative Site, Chattanooga1 trial
  • Monroe Carell Jr Children's Hospital at Vanderbilt, Nashville1 trial
  • Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville1 trial
  • Premier Research Center, LLC, Hendersonville1 trial
  • Research Site, Nashville1 trial
By city

Counts are recruiting studies listing at least one site in Tennessee, from ClinicalTrials.gov, refreshed every two days.

Asthma clinical trials in Tennessee: common questions

How many Asthma clinical trials are recruiting in Tennessee?
TrialFinder currently lists 8 recruiting Asthma clinical trials with study sites in Tennessee. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Asthma clinical trials located in Tennessee?
Study sites for the Asthma trials listed on this page include Nashville. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Asthma clinical trial in Tennessee?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Asthma trials in Tennessee also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Asthma clinical trial in Tennessee?
Each study sets its own criteria based on age, Asthma diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need to stop my inhaler to join an asthma trial?
No. Trials add the study treatment to your maintenance inhaler, or replace it with a study-supplied version, and a rescue inhaler is always permitted. Any change is made by the study doctor.
What is an eosinophil count and why do trials ask about it?
It is a type of white blood cell measured in a routine blood test. Many biologic asthma drugs target the inflammation it signals, so trials set a minimum or maximum count. The site measures it at screening.
Are there asthma trials for children?
Yes. Biologics and inhalers approved for adults are studied in children aged 6 to 11 and in teenagers, with a parent consenting and attending visits. The listing states the age range.
Asthma Trials in Other States
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Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
All guides →

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About Asthma Trials

Asthma trials evaluate biologic therapies, inhaler formulations, allergen immunotherapy, and environmental interventions for moderate-to-severe asthma and COPD overlap.

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