Anxiety Trials / Trials in Missouri
9 Recruiting Trials

Clinical Trials
for Anxiety in Missouri

9 clinical trials for Anxiety are currently recruiting participants at study sites in Missouri. Study-related care is provided at no cost.

9
Recruiting trials
10
Study sites
4
Cities
3
Industry-sponsored
5
Phase 2

Anxiety clinical trials in Missouri: what to expect

Anxiety trials study generalized anxiety disorder, social anxiety, panic disorder and often post-traumatic stress alongside them. The treatments under study range from new medicines and repurposed ones to cognitive behavioral therapy delivered in person, by video or through an app, virtual-reality exposure, and brain stimulation. Many are run by universities and some can be completed largely online, with a small number of in-person visits.

In Missouri, recruiting anxiety studies are concentrated in St Louis, Saint Charles, Columbia and O'Fallon. 3 of the 9 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who anxiety trials usually look for

Trials name the diagnosis they study and set a minimum symptom score on a standard questionnaire, confirmed by a clinician interview at screening. Adults 18 to 65 are the usual range, with separate studies for teenagers and older adults. Typical exclusions are bipolar disorder, psychosis, a current substance use disorder and, for some medicine trials, daily benzodiazepine use. Stable antidepressant treatment is often allowed.

What taking part involves

After a screening interview, medicine trials run eight to twelve weeks with visits every one to two weeks, questionnaires and sometimes blood work; placebo arms are common. Therapy trials involve weekly sessions for eight to sixteen weeks, often with a comparison group that gets the program later. Some studies add brain imaging or a wearable to track sleep and heart rate. Everything study-related is free, and most trials pay for your time.

Questions worth asking the study team

Which visits must be in person; whether you can continue your current medicine or therapy; the chance of placebo or of a waiting-list group; and what support is available if symptoms get worse during the study.

Showing 9 of 9 recruiting Anxiety trials in Missouri

RE104 Safety and Efficacy Study in Generalized Anxiety Disorder
PHASE2 Birmingham, Alabama +4 sites NCT07489651
This trial is looking for people with Generalized Anxiety Disorder (GAD) to see if a single injection of RE104 can help reduce their anxiety symptoms. Participants will be compared to those receiving a placebo, which is an inactive treatment.
Recruiting
Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder
PHASE2 Huntsville, Alabama +4 sites NCT06846320
This trial is looking for adults with generalized anxiety disorder (GAD) who have not had enough relief from their current antidepressant medications. Participants will take capsules of either ABBV-932 or a placebo for 6 weeks, along with their existing treatment, and attend regular check-up visits to monitor their progress.
Recruiting
A Clinical Trial to Assess the Efficacy, Safety, and Tolerability of a Repeat Dose of Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults With Social Anxiety Disorder
PHASE2 Saint Charles, Missouri +4 sites NCT06809179
This trial is looking for adults aged 18 to 65 who have social anxiety disorder. Participants will use a nasal spray to help relieve anxiety symptoms caused by public speaking challenges.
Recruiting
Adolescent Chatbot
PHASE2 St Louis, Missouri NCT07094503
This trial is looking for teenagers aged 13 to 19 who are at risk for eating disorders. Participants will use a chatbot program designed to help prevent eating disorders.
Recruiting
Development of Novel Psychological Assessment Tools and Anxiety Intervention for Phenylketonuria
NA Columbia, Missouri NCT06560736
This trial is looking for adolescents with phenylketonuria (PKU) who want help with anxiety and depression. Participants will take part in a short skills-based program and provide feedback on new assessment tools being developed.
Recruiting
Efficacy of a Multi-level School Intervention for LGBTQ Youth
NA El Monte, California +4 sites NCT05541406
This trial is looking for LGBTQ students attending one of 24 high schools. Participants will take part in a program aimed at addressing issues like bullying and mental health challenges.
Recruiting
Type I Hybrid Effectiveness-Implementation Trial of Primary Care Brief Mindfulness Training for Veterans
NA St Louis, Missouri +3 sites NCT06162741
This trial is looking for Veterans who experience anxiety, depression, or PTSD symptoms. Participants will take part in either a mindfulness class or a problem-solving skills class to see if these help reduce their symptoms.
Recruiting
Leveraging mHealth to Promote Opioid Use Recovery and Mental Health Among Residents of a Medium-Sized Midwestern City
PHASE2 St Louis, Missouri NCT07673380
This trial is looking for Black adults who have used opioids or stimulants and are seeking treatment for substance use. Participants will help test a mobile health program designed to support their recovery journey.
Recruiting
Just-In-Time Adaptive Interventions (JITAIs) in a Digital Mental Health Intervention for Middle-Aged and Older Adults With Chronic Pain
NA St Louis, Missouri NCT06978166
This trial is looking for adults aged 45 and older who have chronic pain and experience symptoms of depression or anxiety. Participants will use a mobile app designed to help manage their conditions and complete some surveys about their mood and physical health.
Recruiting
See all 9 Anxiety trials in Missouri

Where the Anxiety studies are in Missouri

Research sites running the most studies
  • Washington University in St. Louis, St Louis2 trials
  • Arch Clinical Trials /ID# 267851, St Louis1 trial
  • Midwest Research Group, Saint Charles1 trial
  • Psychiatric Care And Research Center /ID# 271701, O'Fallon1 trial
  • Saint Charles Psychiatric Associates /ID# 271202, Saint Charles1 trial
  • St. Louis VA Medical Center John Cochran Division, St. Louis, MO, St Louis1 trial
By city

Counts are recruiting studies listing at least one site in Missouri, from ClinicalTrials.gov, refreshed every two days.

Anxiety clinical trials in Missouri: common questions

How many Anxiety clinical trials are recruiting in Missouri?
TrialFinder currently lists 9 recruiting Anxiety clinical trials with study sites in Missouri. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Anxiety clinical trials located in Missouri?
Study sites for the Anxiety trials listed on this page include Saint Charles, St Louis, Columbia. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Anxiety clinical trial in Missouri?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Anxiety trials in Missouri also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Anxiety clinical trial in Missouri?
Each study sets its own criteria based on age, Anxiety diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Can I take part in an anxiety trial if I am already in therapy?
Often yes for medicine trials, if the therapy is ongoing and stable. Trials testing a therapy usually ask that you are not starting another one at the same time. The listing states its rule.
Are there anxiety studies I can do online?
Yes. Many app-based and video-therapy studies are mostly remote, though most still need one or two in-person visits, so distance to the site still matters.
Is there a placebo in anxiety trials?
Medicine trials usually include a placebo arm and say so in the consent form. Therapy trials compare against usual care or a group that receives the program after a delay.
Anxiety Trials in Other States
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Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
All guides →

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About Anxiety Trials

Anxiety disorder trials study CBT approaches, novel anxiolytics, MDMA-assisted therapy, and neuromodulation techniques for GAD, social anxiety, and PTSD.

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