402 Recruiting Trials

Clinical Trials
for Cancer in Colorado

402 clinical trials for Cancer are currently recruiting participants at study sites in Colorado. Study-related care is provided at no cost.

402
Recruiting trials
399
Study sites
31
Cities
256
Industry-sponsored
149
Phase 2
140
Phase 3

Cancer clinical trials in Colorado: what to expect

Cancer is the single largest area of clinical research, and nearly every recruiting cancer trial is written for one cancer type at one stage. Most test a new drug or combination against the current standard treatment: targeted medicines matched to a mutation found in the tumor, immunotherapies that help the immune system recognize cancer cells, antibody-drug conjugates and cell therapies. Others study surgery and radiation techniques, ways to reduce side effects, and screening or prevention in people at higher risk.

In Colorado, recruiting cancer studies are concentrated in Aurora, Denver, Lone Tree and Colorado Springs, with sites in 27 other cities. 256 of the 402 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who cancer trials usually look for

Every listing names the cancer type and stage it enrolls, and most also state how many earlier treatments you may have had: some are for people newly diagnosed, many are for cancer that has come back or spread after a first treatment stopped working. Targeted-therapy trials require a specific result on tumor testing, which the site can arrange if it has not been done. Trials generally ask that you are well enough for daily activity (a "performance status" the doctor scores), that blood counts and liver and kidney function are adequate, and that a few weeks have passed since your last treatment.

Having advanced or metastatic cancer does not rule you out. A large share of recruiting trials are designed specifically for it.

What taking part involves

Screening reviews your pathology and scans, often with new blood work and sometimes a fresh biopsy. Treatment then follows a cycle, typically every two or three weeks, with scans every six to twelve weeks to measure the response. Early-phase trials have more frequent visits at the start. The study drug and study-specific tests are provided at no cost; standard care that you would receive anyway is usually billed to insurance as normal. A placebo on its own is rare in cancer trials: when there is one, it is added to the standard treatment, and the consent form says so.

Questions worth asking the study team

Whether the trial is randomized and what the comparison treatment is; what happens if the cancer grows during the study; whether you can keep receiving the drug afterward if it is working; how the trial fits with the plan your own oncologist has suggested; and what travel or lodging support is offered. Your oncologist can also refer you directly.

Showing 20 of 402 recruiting Cancer trials in Colorado

Pan Tumor Rollover Study
PHASE2 Huntsville, Alabama +4 sites NCT03899155
This trial is looking for patients with cancer who have had a good response to previous treatments. Participants will continue receiving nivolumab alone or in combination with other cancer therapies to study long-term safety.
Recruiting
ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors
PHASE1 Aurora, Colorado +4 sites NCT03686124
This trial is looking for patients with certain types of cancer that keep coming back or do not respond to standard treatments. Participants will receive the study treatment IMA203/IMA203CD8, either alone or with nivolumab.
Recruiting
Survivors Uniting for Remote Guided Exercise
NA Fort Collins, Colorado NCT07290309
This trial is looking for cancer survivors to participate in a guided online exercise program. Participants will join group workouts over 12 weeks to help improve their physical activity and reduce feelings of loneliness.
Recruiting
Connect for Cancer Prevention Study (Connect)
N/A Denver, Colorado +4 sites NCT04609072
This trial is looking for adults between 30 and 70 years old who have never had cancer. Participants will help researchers learn about cancer risk by answering online health surveys and donating blood, urine, and saliva samples.
Recruiting
Prospective Study to Assess a Diagnostic Aid for Cancer
N/A Centennial, Colorado +4 sites NCT07046260
This trial is looking for people aged 45 and older who have symptoms that might suggest cancer. Participants will take a blood test and may also have additional standard tests to see if cancer is present.
Recruiting
Childhood Cancer Survivor Study
N/A Birmingham, Alabama +4 sites NCT01120353
This trial is looking for childhood cancer survivors who were diagnosed before age 21 and survived for at least five years. Participants will be followed to understand the long-term effects of their cancer treatments.
Recruiting
Integrated Cancer Repository for Cancer Research
N/A Greenwood Village, Colorado +4 sites NCT02012699
This trial is looking for adults who have a history of cancer, are at risk for developing cancer, or are healthy individuals. Participants will provide consent and may help advance cancer research by sharing data and samples.
Recruiting
Microbiome in Head and Neck Squamous Cell Carcinoma
N/A Aurora, Colorado NCT05837221
This trial is looking for adults with oral cancer and those who do not have it. Participants will help researchers understand the role of bacteria in this type of cancer.
Recruiting
A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)
PHASE3 Tucson, Arizona +4 sites NCT06136650
This trial is looking for men with metastatic castration-resistant prostate cancer who have been treated with one hormonal therapy before. Participants will receive either opevesostat with corticosteroids or other alternative treatments to see which is more effective.
Recruiting
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
PHASE3 Goodyear, Arizona +4 sites NCT07213674
This trial is looking for men with specific advanced prostate cancer who have not received chemotherapy. Participants will receive a combination of two medications to see how well they work compared to other treatment options.
Recruiting
A Safety and Efficacy Study of EIK1001 in Combination With Pembrolizumab and Chemotherapy in Participants With Stage 4 Non-Small Cell Lung Cancer.
PHASE2 Pueblo, Colorado +4 sites NCT07365319
This trial is looking for adults with stage 4 non-small cell lung cancer. Participants will receive a treatment combining EIK1001, pembrolizumab, and chemotherapy to assess safety and effectiveness.
Recruiting
Phase IIIb Study of Ribociclib + ET in Early Breast Cancer
PHASE3 Birmingham, Alabama +4 sites NCT05827081
This trial is looking for adults with early breast cancer that is hormone receptor positive and HER2 negative. If you join, you will receive ribociclib along with standard hormone therapy to see how effective this combination is.
Recruiting
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
PHASE3 Birmingham, Alabama +4 sites NCT06058377
This trial is looking for women with hormone receptor positive, HER2 negative stage II-III breast cancer. Participants will receive standard chemotherapy along with an immunotherapy drug called durvalumab to see if it helps prevent cancer from coming back.
Recruiting
A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.
PHASE3 Anchorage, Alaska +4 sites NCT07062965
This trial is looking for people with HR-positive, HER2-negative advanced breast cancer that has worsened after previous treatment. Participants will receive the study medicine PF-07248144 along with their normal treatment options to see how well they work together.
Recruiting
A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014)
PHASE3 Aurora, Colorado +4 sites NCT07513376
This trial is looking for people with high-risk non-small cell lung cancer that has been surgically removed. Participants will receive either one or two investigational treatments to help prevent the cancer from coming back after surgery.
Recruiting
A Study to Access Intravenous (IV) Telisotuzumab Adizutecan in Combination With IV Bevacizumab Compared to Standard of Care IV Bevacizumabin Combination With Oral Trifluridine and Tipiracil in Adult Participants With Refractory Metastatic Colorectal Cancer
PHASE3 Aurora, Colorado +4 sites NCT07525206
This trial is looking for adults with hard-to-treat metastatic colorectal cancer. Participants will receive either a new treatment involving telisotuzumab adizutecan combined with bevacizumab or the current standard treatment and will have regular medical check-ups during the study.
Recruiting
AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)
PHASE3 Dothan, Alabama +4 sites NCT07611110
This trial is looking for men with advanced prostate cancer that hasn't responded to standard treatments. Participants will receive AZD2265 to see if it works better than standard care.
Recruiting

Where the Cancer studies are in Colorado

  • UCHealth University of Colorado Hospital, Aurora43 trials
  • Poudre Valley Hospital, Fort Collins32 trials
  • Medical Center of the Rockies, Loveland31 trials
  • UCHealth Memorial Hospital Central, Colorado Springs31 trials
  • University of Colorado Cancer Center, Aurora31 trials
  • Cancer Care and Hematology-Fort Collins, Fort Collins30 trials

Counts are recruiting studies listing at least one site in Colorado, from ClinicalTrials.gov, refreshed every two days.

Cancer clinical trials in Colorado: common questions

How many Cancer clinical trials are recruiting in Colorado?
TrialFinder currently lists 402 recruiting Cancer clinical trials with study sites in Colorado. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Cancer clinical trials located in Colorado?
Study sites for the Cancer trials listed on this page include Aurora, Fort Collins, Denver, Centennial, Greenwood Village, Pueblo. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Cancer clinical trial in Colorado?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Cancer trials in Colorado also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Cancer clinical trial in Colorado?
Each study sets its own criteria based on age, Cancer diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Will I get a placebo instead of cancer treatment?
Almost never. Cancer trials compare a new treatment with the current standard treatment, or add the study drug to standard treatment. When a placebo is used it is on top of standard care, and the consent form states this before you decide.
Can I join a cancer trial if my cancer has spread?
Yes. Many recruiting cancer trials are written for advanced or metastatic disease, including people whose earlier treatments have stopped working. The listing states the stage and prior treatments it accepts.
Do I have to stop my current cancer treatment to join a trial?
It depends on the trial. Some enroll people whose current treatment has stopped working, some add the study drug to the treatment you are on, and some are for people who have not started treatment yet. Ask the study team before changing anything.
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