101 Recruiting Trials

Clinical Trials
for Cancer in Delaware

101 clinical trials for Cancer are currently recruiting participants at study sites in Delaware. Study-related care is provided at no cost.

101
Recruiting trials
41
Study sites
9
Cities
35
Industry-sponsored
27
Phase 2
62
Phase 3

Cancer clinical trials in Delaware: what to expect

Cancer is the single largest area of clinical research, and nearly every recruiting cancer trial is written for one cancer type at one stage. Most test a new drug or combination against the current standard treatment: targeted medicines matched to a mutation found in the tumor, immunotherapies that help the immune system recognize cancer cells, antibody-drug conjugates and cell therapies. Others study surgery and radiation techniques, ways to reduce side effects, and screening or prevention in people at higher risk.

In Delaware, recruiting cancer studies are concentrated in Newark, Rehoboth Beach, Wilmington and Millville, with sites in 5 other cities. 35 of the 101 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who cancer trials usually look for

Every listing names the cancer type and stage it enrolls, and most also state how many earlier treatments you may have had: some are for people newly diagnosed, many are for cancer that has come back or spread after a first treatment stopped working. Targeted-therapy trials require a specific result on tumor testing, which the site can arrange if it has not been done. Trials generally ask that you are well enough for daily activity (a "performance status" the doctor scores), that blood counts and liver and kidney function are adequate, and that a few weeks have passed since your last treatment.

Having advanced or metastatic cancer does not rule you out. A large share of recruiting trials are designed specifically for it.

What taking part involves

Screening reviews your pathology and scans, often with new blood work and sometimes a fresh biopsy. Treatment then follows a cycle, typically every two or three weeks, with scans every six to twelve weeks to measure the response. Early-phase trials have more frequent visits at the start. The study drug and study-specific tests are provided at no cost; standard care that you would receive anyway is usually billed to insurance as normal. A placebo on its own is rare in cancer trials: when there is one, it is added to the standard treatment, and the consent form says so.

Questions worth asking the study team

Whether the trial is randomized and what the comparison treatment is; what happens if the cancer grows during the study; whether you can keep receiving the drug afterward if it is working; how the trial fits with the plan your own oncologist has suggested; and what travel or lodging support is offered. Your oncologist can also refer you directly.

Showing 20 of 101 recruiting Cancer trials in Delaware

A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
PHASE3 Goodyear, Arizona +4 sites NCT07213674
This trial is looking for men with specific advanced prostate cancer who have not received chemotherapy. Participants will receive a combination of two medications to see how well they work compared to other treatment options.
Recruiting
Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial
PHASE3 Jonesboro, Arkansas +4 sites NCT07391774
This trial is looking for women who are postmenopausal and have high stage breast cancer that is less likely to come back. Participants will compare hormone therapy and ribociclib to chemotherapy followed by hormone therapy and ribociclib.
Recruiting
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
PHASE3 Birmingham, Alabama +4 sites NCT06058377
This trial is looking for women with hormone receptor positive, HER2 negative stage II-III breast cancer. Participants will receive standard chemotherapy along with an immunotherapy drug called durvalumab to see if it helps prevent cancer from coming back.
Recruiting
A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer
PHASE3 Anchorage, Alaska +4 sites NCT06764875
This trial is looking for individuals with advanced stomach cancer that tests positive for HER2. Participants will receive a combination of rilvegostomig, chemotherapy, and other treatments to see how well it works.
Recruiting
Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
PHASE3 Huntsville, Alabama +4 sites NCT07562152
This trial is looking for adults with advanced pancreatic cancer. Participants will receive a combination treatment to see how effective and safe it is compared to standard treatment.
Recruiting
A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
PHASE3 Newark, Delaware +4 sites NCT05920356
This trial is looking for people with advanced non-small cell lung cancer who have a specific gene mutation. Participants will receive one of two treatment combinations and will be monitored for their cancer's progress.
Recruiting
Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)
PHASE3 Mobile, Alabama +4 sites NCT06393374
This trial is looking for adults with a specific type of breast cancer called triple-negative breast cancer who didn’t have a full response to their initial treatment. They need to have recently had surgery and recovered well, and they should not have certain complicated health issues like severe nerve pain or a known genetic mutation linked to breast cancer. Additionally, the trial is not for people who have serious eye problems or are currently pregnant or breastfeeding.
Recruiting
Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations
PHASE3 Chandler, Arizona +4 sites NCT07291037
This trial is looking for patients with advanced lung cancer that tests positive for a specific protein. Participants will receive either datopotamab deruxtecan or docetaxel as treatment.
Recruiting
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
PHASE3 Mobile, Alabama +4 sites NCT07228832
This trial is looking for patients with metastatic colorectal cancer who have not received any previous treatment. Participants will receive either Ivonescimab or Bevacizumab combined with chemotherapy as their first treatment.
Recruiting
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
PHASE3 Phoenix, Arizona +4 sites NCT06876714
This trial is looking for adults with HER2-positive breast cancer who have no residual invasive disease after chemotherapy. Participants will receive either 6 or 12 months of HER2-targeted medications to see which duration works best.
Recruiting
A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC
PHASE3 Mobile, Alabama +4 sites NCT06627647
This trial is looking for adults with a specific type of lung cancer that has spread and has specific characteristics. Participants will receive one of two treatments combined with chemotherapy as part of their first treatment plan.
Recruiting
A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion
PHASE2 Anchorage, Alaska +4 sites NCT07063745
This trial is looking for people with advanced lung cancer who have a specific genetic change. Participants will receive either a combination of Navlimetostat, pembrolizumab, and chemotherapy or a placebo with the same treatments.
Recruiting
A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)
PHASE3 Tucson, Arizona +4 sites NCT06692738
This trial is looking for adults with a specific type of lung cancer that has spread or is hard to treat. Participants will receive a combination of a new drug and chemotherapy as their first treatment.
Recruiting
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
PHASE3 Birmingham, Alabama +4 sites NCT05879926
This trial is looking for premenopausal women with early-stage breast cancer that is hormone receptor-positive. Participants will receive hormone therapy and may also get chemotherapy to see if it helps them live longer without cancer returning.
Recruiting
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
PHASE3 Birmingham, Alabama +4 sites NCT05812807
This trial is looking for people with early-stage triple-negative breast cancer who had no cancer left after previous treatments. Participants will either continue receiving pembrolizumab or just be monitored after surgery to see which approach works better to prevent cancer from coming back.
Recruiting
Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer
PHASE3 Phoenix, Arizona +4 sites NCT06205485
This trial is looking for people with rectal cancer to compare two treatment options. Participants will receive either chemotherapy alone or chemotherapy with radiation before surgery.
Recruiting
Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response
PHASE3 Anchorage, Alaska +4 sites NCT06592924
This trial is looking for men with prostate cancer that has spread and is responding poorly to current treatment. Participants will receive additional medication to see if it helps lower cancer growth and spread.
Recruiting
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
PHASE2 Birmingham, Alabama +4 sites NCT03851445
This trial is looking for patients with previously treated non-small cell lung cancer. Participants will undergo testing and may receive new therapies that target cancer growth compared to standard treatments.
Recruiting

Where the Cancer studies are in Delaware

  • Helen F Graham Cancer Center, Newark53 trials
  • Medical Oncology Hematology Consultants PA, Newark52 trials
  • Beebe Health Campus, Rehoboth Beach36 trials
  • Beebe South Coastal Health Campus, Millville33 trials
  • Christiana Care Health System-Christiana Hospital, Newark27 trials
  • Christiana Care Health System-Wilmington Hospital, Wilmington27 trials

Counts are recruiting studies listing at least one site in Delaware, from ClinicalTrials.gov, refreshed every two days.

Cancer clinical trials in Delaware: common questions

How many Cancer clinical trials are recruiting in Delaware?
TrialFinder currently lists 101 recruiting Cancer clinical trials with study sites in Delaware. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Cancer clinical trials located in Delaware?
Study sites for the Cancer trials listed on this page include Newark. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Cancer clinical trial in Delaware?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Cancer trials in Delaware also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Cancer clinical trial in Delaware?
Each study sets its own criteria based on age, Cancer diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Will I get a placebo instead of cancer treatment?
Almost never. Cancer trials compare a new treatment with the current standard treatment, or add the study drug to standard treatment. When a placebo is used it is on top of standard care, and the consent form states this before you decide.
Can I join a cancer trial if my cancer has spread?
Yes. Many recruiting cancer trials are written for advanced or metastatic disease, including people whose earlier treatments have stopped working. The listing states the stage and prior treatments it accepts.
Do I have to stop my current cancer treatment to join a trial?
It depends on the trial. Some enroll people whose current treatment has stopped working, some add the study drug to the treatment you are on, and some are for people who have not started treatment yet. Ask the study team before changing anything.
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