936 Recruiting Trials

Clinical Trials
for Cancer in Florida

936 clinical trials for Cancer are currently recruiting participants at study sites in Florida. Study-related care is provided at no cost.

936
Recruiting trials
1021
Study sites
105
Cities
558
Industry-sponsored
350
Phase 2
245
Phase 3

Cancer clinical trials in Florida: what to expect

Cancer is the single largest area of clinical research, and nearly every recruiting cancer trial is written for one cancer type at one stage. Most test a new drug or combination against the current standard treatment: targeted medicines matched to a mutation found in the tumor, immunotherapies that help the immune system recognize cancer cells, antibody-drug conjugates and cell therapies. Others study surgery and radiation techniques, ways to reduce side effects, and screening or prevention in people at higher risk.

In Florida, recruiting cancer studies are concentrated in Tampa, Miami, Jacksonville and Orlando, with sites in 101 other cities. 558 of the 936 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who cancer trials usually look for

Every listing names the cancer type and stage it enrolls, and most also state how many earlier treatments you may have had: some are for people newly diagnosed, many are for cancer that has come back or spread after a first treatment stopped working. Targeted-therapy trials require a specific result on tumor testing, which the site can arrange if it has not been done. Trials generally ask that you are well enough for daily activity (a "performance status" the doctor scores), that blood counts and liver and kidney function are adequate, and that a few weeks have passed since your last treatment.

Having advanced or metastatic cancer does not rule you out. A large share of recruiting trials are designed specifically for it.

What taking part involves

Screening reviews your pathology and scans, often with new blood work and sometimes a fresh biopsy. Treatment then follows a cycle, typically every two or three weeks, with scans every six to twelve weeks to measure the response. Early-phase trials have more frequent visits at the start. The study drug and study-specific tests are provided at no cost; standard care that you would receive anyway is usually billed to insurance as normal. A placebo on its own is rare in cancer trials: when there is one, it is added to the standard treatment, and the consent form says so.

Questions worth asking the study team

Whether the trial is randomized and what the comparison treatment is; what happens if the cancer grows during the study; whether you can keep receiving the drug afterward if it is working; how the trial fits with the plan your own oncologist has suggested; and what travel or lodging support is offered. Your oncologist can also refer you directly.

Showing 20 of 936 recruiting Cancer trials in Florida

Pan Tumor Rollover Study
PHASE2 Huntsville, Alabama +4 sites NCT03899155
This trial is looking for patients with cancer who have had a good response to previous treatments. Participants will continue receiving nivolumab alone or in combination with other cancer therapies to study long-term safety.
Recruiting
ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors
PHASE1 Miami, Florida +4 sites NCT03686124
This trial is looking for patients with certain types of cancer that keep coming back or do not respond to standard treatments. Participants will receive the study treatment IMA203/IMA203CD8, either alone or with nivolumab.
Recruiting
Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Cancer
PHASE2 Miami Beach, Florida +4 sites NCT05997017
This trial is looking for women with advanced or recurrent endometrioid endometrial cancer to test a combination of two medications. Participants must have measurable disease and meet certain health criteria to join the study.
Recruiting
A Phase 1 Study of IM-1617 in Participants With Advanced Cancer
PHASE1 Sarasota, Florida +3 sites NCT07578571
This trial is looking for people with advanced solid tumors that cannot be removed with surgery. Participants will receive a drug called IM-1617 to see how safe and effective it is.
Recruiting
Artificial Intelligence-Powered Support For Quality Of Life Improvement In Participants With Cancer
NA Weston, Florida NCT07167056
This trial is looking for people diagnosed with cancer who are receiving treatment and may benefit from therapy. Participants will either use an AI app for support during their therapy sessions or continue therapy without the app. Both groups will share their experiences through surveys.
Recruiting
Expanding the Support of Family Caregivers of Diverse Patients With Cancer and Diabetes
NA Tampa, Florida +2 sites NCT07061652
This trial is looking for caregivers of adults with cancer and diabetes to participate in a support program. Participants will help improve support services for caregivers through a coaching program.
Recruiting
The Florida ASCENT Study
NA Gainesville, Florida NCT07042243
This trial is looking for adults with certain types of cancer in Florida to help improve their access to care and nutrition support. Participants will answer questions about their diet and health and have consultations with a patient navigator.
Recruiting
xDRIVE for Florida-based Cancer Patients
NA Miami, Florida +1 sites NCT07167381
This trial is looking for cancer patients in Florida, particularly those who are underserved. Participants will use a new platform to help their doctors understand their treatment options better.
Recruiting
INTERogating Cancer for Etiology, Prevention and Therapy Navigation
N/A Jacksonville, Florida +4 sites NCT06008392
This trial is looking for people with a confirmed diagnosis of cancer. Participants will provide samples like blood or tissue to help researchers understand cancer better and improve treatments.
Recruiting
Met Non Small Cell Cancer Registry (MOMENT)
N/A Fort Lauderdale, Florida +4 sites NCT05376891
This trial is looking for people with advanced non-small cell lung cancer who have certain genetic changes. Participants will share their treatment experiences and outcomes as part of a larger study.
Recruiting
Prospective Study to Assess a Diagnostic Aid for Cancer
N/A Coconut Creek, Florida +4 sites NCT07046260
This trial is looking for people aged 45 and older who have symptoms that might suggest cancer. Participants will take a blood test and may also have additional standard tests to see if cancer is present.
Recruiting
A Multilevel Approach to Connecting Underrepresented Populations to Clinical Trials
N/A Gainesville, Florida +2 sites NCT05655494
This trial is looking for Black and Hispanic adult cancer patients and their family members to help test a program that connects them to clinical trials. Participants will need to use email or texts to communicate and will be contacted again after joining.
Recruiting
Multi-Cancer Detection Observational Cohort Study
N/A Jacksonville, Florida +2 sites NCT06962995
This trial is looking for adults who have had or are scheduled for a multi-cancer detection test. Participants will help researchers understand how this test works in real-life healthcare settings.
Recruiting
Integrated Cancer Repository for Cancer Research
N/A Daytona Beach, Florida +4 sites NCT02012699
This trial is looking for adults who have a history of cancer, are at risk for developing cancer, or are healthy individuals. Participants will provide consent and may help advance cancer research by sharing data and samples.
Recruiting
A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)
PHASE3 Tucson, Arizona +4 sites NCT06136650
This trial is looking for men with metastatic castration-resistant prostate cancer who have been treated with one hormonal therapy before. Participants will receive either opevesostat with corticosteroids or other alternative treatments to see which is more effective.
Recruiting
A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)
PHASE3 Miami Beach, Florida +4 sites NCT06345729
This trial is looking for adults diagnosed with a specific type of lung cancer called non-small cell lung cancer (NSCLC) that has a certain genetic mutation. Participants will receive a combination of two drugs, calderasib and pembrolizumab, to see how well they work together as a first treatment option.
Recruiting
Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer
PHASE3 Miami, Florida +4 sites NCT06801834
This trial is looking for patients with extensive stage small cell lung cancer that has been treated before. Participants will receive the study drug sacituzumab govitecan to see how it works compared to standard treatment.
Recruiting
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
PHASE3 Goodyear, Arizona +4 sites NCT07213674
This trial is looking for men with specific advanced prostate cancer who have not received chemotherapy. Participants will receive a combination of two medications to see how well they work compared to other treatment options.
Recruiting
A Safety and Efficacy Study of EIK1001 in Combination With Pembrolizumab and Chemotherapy in Participants With Stage 4 Non-Small Cell Lung Cancer.
PHASE2 Plantation, Florida +4 sites NCT07365319
This trial is looking for adults with stage 4 non-small cell lung cancer. Participants will receive a treatment combining EIK1001, pembrolizumab, and chemotherapy to assess safety and effectiveness.
Recruiting
Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial
PHASE3 Jonesboro, Arkansas +4 sites NCT07391774
This trial is looking for women who are postmenopausal and have high stage breast cancer that is less likely to come back. Participants will compare hormone therapy and ribociclib to chemotherapy followed by hormone therapy and ribociclib.
Recruiting

Where the Cancer studies are in Florida

  • Moffitt Cancer Center, Tampa158 trials
  • Mayo Clinic in Florida, Jacksonville81 trials
  • University of Miami, Miami51 trials
  • University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami38 trials
  • Mount Sinai Medical Center, Miami Beach32 trials
  • UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables30 trials

Counts are recruiting studies listing at least one site in Florida, from ClinicalTrials.gov, refreshed every two days.

Cancer clinical trials in Florida: common questions

How many Cancer clinical trials are recruiting in Florida?
TrialFinder currently lists 936 recruiting Cancer clinical trials with study sites in Florida. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Cancer clinical trials located in Florida?
Study sites for the Cancer trials listed on this page include Miami, Miami Beach, Sarasota, Weston, Tampa, Gainesville. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Cancer clinical trial in Florida?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Cancer trials in Florida also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Cancer clinical trial in Florida?
Each study sets its own criteria based on age, Cancer diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Will I get a placebo instead of cancer treatment?
Almost never. Cancer trials compare a new treatment with the current standard treatment, or add the study drug to standard treatment. When a placebo is used it is on top of standard care, and the consent form states this before you decide.
Can I join a cancer trial if my cancer has spread?
Yes. Many recruiting cancer trials are written for advanced or metastatic disease, including people whose earlier treatments have stopped working. The listing states the stage and prior treatments it accepts.
Do I have to stop my current cancer treatment to join a trial?
It depends on the trial. Some enroll people whose current treatment has stopped working, some add the study drug to the treatment you are on, and some are for people who have not started treatment yet. Ask the study team before changing anything.
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