Obesity Trials / Trials in Florida
89 Recruiting Trials

Clinical Trials
for Obesity in Florida

89 clinical trials for Obesity are currently recruiting participants at study sites in Florida. Study-related care is provided at no cost.

89
Recruiting trials
273
Study sites
73
Cities
68
Industry-sponsored
10
Phase 2
47
Phase 3

Obesity clinical trials in Florida: what to expect

Obesity trials are among the most actively recruiting studies in the United States right now. Most test medicines from the GLP-1 family (the class that includes semaglutide and tirzepatide) or newer compounds that work on the same appetite and blood-sugar pathways, often in people who also have high blood pressure, sleep apnea, knee osteoarthritis or prediabetes. A smaller number study structured diet and exercise programs, devices, or weight-loss surgery.

In Florida, recruiting obesity studies are concentrated in Miami, Jacksonville, Orlando and Tampa, with sites in 69 other cities. 68 of the 89 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who obesity trials usually look for

Nearly every study sets a body mass index (BMI) threshold, most often 30 or higher, or 27 or higher when you also have a weight-related condition. Many ask that your weight has been stable for the last three months and that you are not currently using a prescription weight-loss drug. Age limits of 18 to 75 are common. Pregnancy, a history of pancreatitis or certain thyroid cancers, and bariatric surgery within the last few years are the exclusions that come up most.

If you have type 2 diabetes, look for trials that name it: some obesity studies exclude diabetes, while others are designed specifically for people who have both.

What taking part involves

A screening visit with a physical exam, blood work and an ECG usually comes first. Drug trials then run for six months to two years, with study visits every few weeks at the start and every one to three months later on. Most GLP-1 studies use a once-weekly injection you give yourself at home; many are placebo-controlled, meaning some participants receive an inactive version for part or all of the study, and you are told that before you agree to join. Study medication, visits and tests are provided at no cost, and most trials pay a stipend for time and travel.

Questions worth asking the study team

Whether there is a placebo group and how long it lasts; whether you can continue the medicine after the study ends; how many visits are required and how far the site is from you; and what happens if you need to stop early. Sites answer these every day and a ten-minute phone screen is the normal next step.

Showing 20 of 89 recruiting Obesity trials in Florida

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
PHASE3 Birmingham, Alabama +4 sites NCT07654374
This trial is looking for adults with obesity or overweight who also have type 2 diabetes. Participants will take either the drug aleniglipron or a placebo for 76 weeks to assess its effects.
Recruiting
A Study to Learn About Switching to a Monthly Study Medicine Called Berobenatide (PF-08653944) to Help Keep Weight Off in People With Overweight or Obesity
PHASE3 Jacksonville, Florida +4 sites NCT07845500
Recruiting
A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity
PHASE3 Canoga Park, California +4 sites NCT07595549
This trial is looking for adults with overweight or obesity who may also have type 2 diabetes. Participants will get either a shot of the study medicine, berobenatide, or a placebo that doesn't contain any medicine. The study lasts for about 20 months and involves regular visits to check on health and weight.
Recruiting
Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS)
PHASE3 Tucson, Arizona +4 sites NCT07817875
This trial is looking for children aged 6 to less than 12 years who have obesity. Participants will try a new treatment along with healthy lifestyle changes for about two years.
Recruiting
A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)
PHASE3 Tucson, Arizona +4 sites NCT06672549
This trial is looking for teens aged 12 to under 18 who are struggling with obesity or being overweight. Participants must have tried losing weight before but were unsuccessful.
Recruiting
AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea
PHASE3 Bradenton, Florida +4 sites NCT07571109
This trial is looking for adults with obesity or overweight who also have obstructive sleep apnoea and are using a breathing device. Participants will receive a weekly injection either of the study medication or a placebo with no active ingredients.
Recruiting
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)
PHASE3 Gilbert, Arizona +4 sites NCT07684144
This trial is looking for people with obesity and type 2 diabetes who have completed a previous study. Participants will take a medication to see how it works over a longer time period, while following specific rules during the trial.
Recruiting
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)
PHASE3 Anniston, Alabama +4 sites NCT07684235
This trial is looking for individuals with obesity or overweight who have completed a previous trial. Participants will receive maridebart cafraglutide and be monitored for safety and effectiveness over a longer period.
Recruiting
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
PHASE3 Birmingham, Alabama +4 sites NCT07564414
This trial is looking for people with obesity, with or without type 2 diabetes, who want to lose weight. Participants will be assigned by chance to receive either CagriSema or semaglutide for about 83 weeks.
Recruiting
AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight
PHASE3 Miramar, Florida +4 sites NCT07339423
This trial is looking for people with excess body weight who want to lose weight. Participants will receive either the treatment NNC0487-0111 or a placebo injection once a week.
Recruiting
A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
PHASE3 Tuscaloosa, Alabama +4 sites NCT07321886
This trial is looking for adults who are overweight or have obesity but do not have type 2 diabetes. Participants will take eloralintide for a main phase lasting about 75 weeks, with an option to continue for another 2 years if they have prediabetes.
Recruiting
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes
PHASE3 Birmingham, Alabama +4 sites NCT07743450
This trial is looking for adults with obesity or overweight who have type 2 diabetes. Participants will take a daily oral medication to see how well it works and how safe it is over time.
Recruiting
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities
PHASE3 Birmingham, Alabama +4 sites NCT07743463
This trial is looking for adults who are overweight or obese and have weight-related health problems. Participants will take a daily pill for the study to see how well it helps with weight management and its safety.
Recruiting
AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea
PHASE3 Miami, Florida +4 sites NCT07571005
This trial is looking for people with excess weight and sleep apnoea that is not treated with breathing devices. Participants will receive an injection either of the study drug or a placebo once a week for a certain period.
Recruiting
Efficacy and Safety of Ribupatide in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes
PHASE3 Anniston, Alabama +4 sites NCT07284875
This trial is looking for people who are overweight or living with obesity and have related health issues, but do not have diabetes. Participants will receive a weekly injection of ribupatide or a placebo to see how it affects their weight.
Recruiting
Efficacy and Safety of Ribupatide Administered Once Weekly Compared With Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have Diabetes
PHASE3 Glendale, Arizona +4 sites NCT07284979
This trial is looking for individuals living with obesity who have struggled to lose weight through diet and exercise. Participants will receive a weekly injection of ribupatide and will be compared to those receiving semaglutide or a placebo.
Recruiting
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
PHASE3 Alexander City, Alabama +4 sites NCT07567001
This trial is looking for individuals with heart failure who are also obese. Participants will receive either an injection of NNC0487-0111 or a placebo once a week to see how well it works and how safe it is.
Recruiting
AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
PHASE3 Jacksonville, Florida +4 sites NCT07509307
This trial is looking for people with excess weight and knee osteoarthritis. Participants will receive an injection either of the study medicine or a placebo once a week for a set period of time.
Recruiting
Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)
PHASE3 Birmingham, Alabama +4 sites NCT07654361
This trial is looking for adults with obesity or overweight who have health problems related to their weight. Participants will take a daily medication called aleniglipron for at least 76 weeks while following a reduced-calorie diet and increasing physical activity.
Recruiting
A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
PHASE3 Hollywood, Florida +4 sites NCT07481630
This trial is looking for adults with knee osteoarthritis and extra body weight. Participants will receive either an injection of NNC0487-0111 or a placebo once a week to see how it helps with weight loss and pain reduction.
Recruiting
See all 89 Obesity trials in Florida

Where the Obesity studies are in Florida

Research sites running the most studies
  • New Horizon Research Center, Miami7 trials
  • Encore Medical Research LLC, Hollywood5 trials
  • Florida State University, Tallahassee5 trials
  • Jacksonville Center for Clinical Research, Jacksonville5 trials
  • Northeast Research Institute, Fleming Island5 trials
  • Progressive Medical Research, Port Orange5 trials
By city

Counts are recruiting studies listing at least one site in Florida, from ClinicalTrials.gov, refreshed every two days.

Obesity clinical trials in Florida: common questions

How many Obesity clinical trials are recruiting in Florida?
TrialFinder currently lists 89 recruiting Obesity clinical trials with study sites in Florida. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Obesity clinical trials located in Florida?
Study sites for the Obesity trials listed on this page include Jacksonville, Bradenton, Miramar, Miami, Hollywood. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Obesity clinical trial in Florida?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Obesity trials in Florida also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Obesity clinical trial in Florida?
Each study sets its own criteria based on age, Obesity diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need a BMI over 30 to join an obesity clinical trial?
Most adult obesity trials require a BMI of 30 or higher, or 27 or higher if you also have a weight-related condition such as high blood pressure, prediabetes or sleep apnea. Each trial page lists its exact threshold.
Are obesity trial participants paid?
Study medication, visits and tests are provided free, and most obesity trials pay a stipend per visit for time and travel. The amount is set by each study and told to you before you enroll; it is never contingent on finishing the study.
Obesity Trials in Other States
Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware District of Columbia Georgia Hawaii Idaho Illinois Indiana Iowa Kansas Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Mississippi Missouri Montana Nebraska Nevada New Hampshire New Jersey New Mexico New York North Carolina North Dakota Ohio Oklahoma Oregon Pennsylvania Rhode Island South Carolina South Dakota Tennessee Texas Utah Vermont Virginia Washington West Virginia Wisconsin Wyoming
Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
All guides →

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About Obesity Trials

Obesity trials study GLP-1 receptor agonists, bariatric procedures, behavioural interventions, and combination weight-loss therapies in adults and adolescents.

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