32 Recruiting Trials

Clinical Trials
for Obesity in Oklahoma

32 clinical trials for Obesity are currently recruiting participants at study sites in Oklahoma. Study-related care is provided at no cost.

32
Recruiting trials
29
Study sites
8
Cities
23
Industry-sponsored
4
Phase 2
21
Phase 3

Obesity clinical trials in Oklahoma: what to expect

Obesity trials are among the most actively recruiting studies in the United States right now. Most test medicines from the GLP-1 family (the class that includes semaglutide and tirzepatide) or newer compounds that work on the same appetite and blood-sugar pathways, often in people who also have high blood pressure, sleep apnea, knee osteoarthritis or prediabetes. A smaller number study structured diet and exercise programs, devices, or weight-loss surgery.

In Oklahoma, recruiting obesity studies are concentrated in Oklahoma City, Tulsa, Norman and Chickasha, with sites in 4 other cities. 23 of the 32 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who obesity trials usually look for

Nearly every study sets a body mass index (BMI) threshold, most often 30 or higher, or 27 or higher when you also have a weight-related condition. Many ask that your weight has been stable for the last three months and that you are not currently using a prescription weight-loss drug. Age limits of 18 to 75 are common. Pregnancy, a history of pancreatitis or certain thyroid cancers, and bariatric surgery within the last few years are the exclusions that come up most.

If you have type 2 diabetes, look for trials that name it: some obesity studies exclude diabetes, while others are designed specifically for people who have both.

What taking part involves

A screening visit with a physical exam, blood work and an ECG usually comes first. Drug trials then run for six months to two years, with study visits every few weeks at the start and every one to three months later on. Most GLP-1 studies use a once-weekly injection you give yourself at home; many are placebo-controlled, meaning some participants receive an inactive version for part or all of the study, and you are told that before you agree to join. Study medication, visits and tests are provided at no cost, and most trials pay a stipend for time and travel.

Questions worth asking the study team

Whether there is a placebo group and how long it lasts; whether you can continue the medicine after the study ends; how many visits are required and how far the site is from you; and what happens if you need to stop early. Sites answer these every day and a ten-minute phone screen is the normal next step.

Showing 20 of 32 recruiting Obesity trials in Oklahoma

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
PHASE3 Birmingham, Alabama +4 sites NCT07654374
This trial is looking for adults with obesity or overweight who also have type 2 diabetes. Participants will take either the drug aleniglipron or a placebo for 76 weeks to assess its effects.
Recruiting
Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS)
PHASE3 Tucson, Arizona +4 sites NCT07817875
This trial is looking for children aged 6 to less than 12 years who have obesity. Participants will try a new treatment along with healthy lifestyle changes for about two years.
Recruiting
A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)
PHASE3 Tucson, Arizona +4 sites NCT06672549
This trial is looking for teens aged 12 to under 18 who are struggling with obesity or being overweight. Participants must have tried losing weight before but were unsuccessful.
Recruiting
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)
PHASE3 Anniston, Alabama +4 sites NCT07684235
This trial is looking for individuals with obesity or overweight who have completed a previous trial. Participants will receive maridebart cafraglutide and be monitored for safety and effectiveness over a longer period.
Recruiting
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
PHASE3 Birmingham, Alabama +4 sites NCT07564414
This trial is looking for people with obesity, with or without type 2 diabetes, who want to lose weight. Participants will be assigned by chance to receive either CagriSema or semaglutide for about 83 weeks.
Recruiting
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes
PHASE3 Birmingham, Alabama +4 sites NCT07743450
This trial is looking for adults with obesity or overweight who have type 2 diabetes. Participants will take a daily oral medication to see how well it works and how safe it is over time.
Recruiting
Efficacy and Safety of Ribupatide in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes
PHASE3 Anniston, Alabama +4 sites NCT07284875
This trial is looking for people who are overweight or living with obesity and have related health issues, but do not have diabetes. Participants will receive a weekly injection of ribupatide or a placebo to see how it affects their weight.
Recruiting
Efficacy and Safety of Ribupatide Administered Once Weekly Compared With Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have Diabetes
PHASE3 Glendale, Arizona +4 sites NCT07284979
This trial is looking for individuals living with obesity who have struggled to lose weight through diet and exercise. Participants will receive a weekly injection of ribupatide and will be compared to those receiving semaglutide or a placebo.
Recruiting
Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)
PHASE3 Birmingham, Alabama +4 sites NCT07654361
This trial is looking for adults with obesity or overweight who have health problems related to their weight. Participants will take a daily medication called aleniglipron for at least 76 weeks while following a reduced-calorie diet and increasing physical activity.
Recruiting
Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)
PHASE3 Pelham, Alabama +4 sites NCT07575399
This trial is looking for adults who are overweight or obese and have been using a specific medication for weight loss. Participants will switch to taking maridebart cafraglutide and be monitored for effects and side effects.
Recruiting
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
PHASE3 Anniston, Alabama +4 sites NCT07351045
This trial is looking for adults who are overweight or have obesity without type 2 diabetes. Participants will take a study drug or a placebo to help with weight management and will need to self-administer the treatment.
Recruiting
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
PHASE3 Guntersville, Alabama +4 sites NCT07351058
This trial is looking for people with obesity or overweight and type 2 diabetes. Participants will use an injectable medication to help with weight management.
Recruiting
Efficacy and Safety of Ribupatide Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes
PHASE3 Cullman, Alabama +4 sites NCT07284901
This trial is looking for people with obesity or overweight who also have type 2 diabetes. Participants will receive a weekly injection of ribupatide to see how it affects their weight and blood sugar levels.
Recruiting
A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus
PHASE3 Dothan, Alabama +4 sites NCT07784725
This trial is looking for adults with obesity or overweight who have tried to lose weight before. Participants will take AZD6234 or a placebo for 68 weeks to see how it affects weight change.
Recruiting
Phentermine's Impact on Treatment in Teens
PHASE2 Wilmington, Delaware +4 sites NCT07282340
This trial is looking for teens aged 12 to 17 who are dealing with obesity. Participants will take either phentermine or a placebo for a year to see how it helps with weight management.
Recruiting
iAmHealthy Clinical Practice Guideline (CPG)
NA Oklahoma City, Oklahoma +3 sites NCT06888011
This trial is looking for children aged 6-11 years who are overweight and live in rural areas. Participants will either receive a program to help with healthy habits or a newsletter during the study.
Recruiting
Postnatal Exercise to Activate Baby's Brown Fat
NA Oklahoma City, Oklahoma +1 sites NCT07467694
This trial is looking for women aged 18 to 45 who are pregnant or recently gave birth. Participants will engage in exercise to see how it affects their breastmilk and their baby's health.
Recruiting
Study to Assess the Effect and Safety of ALV-100 on Maintenance of Weight Loss
PHASE2 Birmingham, Alabama +4 sites NCT07837973
This trial is looking for adults who have lost weight using a treatment called semaglutide. Participants will help assess the safety and effectiveness of a new medication called ALV-100 while maintaining their current weight loss and lifestyle.
Recruiting
Recruiting

Where the Obesity studies are in Oklahoma

  • Lynn Health Science Institute, Oklahoma City3 trials
  • Lynn Institute of Norman, Norman3 trials
  • Alliance for Multispecialty Research - Norman, Norman2 trials
  • Central States Research, Tulsa2 trials
  • Essential Medical Research, Tulsa2 trials
  • Kailera Clinical Site, Chickasha2 trials

Counts are recruiting studies listing at least one site in Oklahoma, from ClinicalTrials.gov, refreshed every two days.

Obesity clinical trials in Oklahoma: common questions

How many Obesity clinical trials are recruiting in Oklahoma?
TrialFinder currently lists 32 recruiting Obesity clinical trials with study sites in Oklahoma. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Obesity clinical trials located in Oklahoma?
Study sites for the Obesity trials listed on this page include Oklahoma City, Stillwater. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Obesity clinical trial in Oklahoma?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Obesity trials in Oklahoma also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Obesity clinical trial in Oklahoma?
Each study sets its own criteria based on age, Obesity diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need a BMI over 30 to join an obesity clinical trial?
Most adult obesity trials require a BMI of 30 or higher, or 27 or higher if you also have a weight-related condition such as high blood pressure, prediabetes or sleep apnea. Each trial page lists its exact threshold.
Are obesity trial participants paid?
Study medication, visits and tests are provided free, and most obesity trials pay a stipend per visit for time and travel. The amount is set by each study and told to you before you enroll; it is never contingent on finishing the study.
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Obesity trials study GLP-1 receptor agonists, bariatric procedures, behavioural interventions, and combination weight-loss therapies in adults and adolescents.

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