No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 45
Sex
Female
Study type
Interventional
Purpose
Prevention
Participants needed
200 (estimated)
Sponsor
Joslin Diabetes Center · Other
Who this trial is looking for
This trial is looking for women aged 18 to 45 who are pregnant or recently gave birth. Participants will engage in exercise to see how it affects their breastmilk and their baby's health.
Are You a Good Fit for This Trial?
Rules you outUncontrolled diabetesIntrauterine growth restrictionPre-eclampsia
You may be able to join if
I am 18 to 45 years old
I have a healthy weight before pregnancy or in early pregnancy
I am having a single baby without complications
I plan to breastfeed exclusively for more than 3 months
I am in the later stages of pregnancy, between 37 and 42 weeks
My baby is born with a weight in the normal range
You may not be able to join if
I have a condition that prevents me from exercising
I have uncontrolled diabetes
I have had pregnancy complications
I use alcohol, cannabis, or tobacco
I have certain serious congenital illnesses
My baby has major birth defects
I have musculoskeletal problems that affect my ability to exercise
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The purpose of this study is to learn how exercise and physical activity during pregnancy and after pregnancy may affect the composition of breastmilk. Certain changes in breast milk after exercise may have an impact on how infants use energy. Understanding this process may improve public health recommendations for exercise during and after pregnancy. This study can help investigators learn more a…
The purpose of this study is to learn how exercise and physical activity during pregnancy and after pregnancy may affect the composition of breastmilk. Certain changes in breast milk after exercise may have an impact on how infants use energy. Understanding this process may improve public health recommendations for exercise during and after pregnancy. This study can help investigators learn more about how maternal exercise patterns may affect body growth and obesity risk in infants who are breastfed. This research may help identify how different factors can influence healthy weight and early development in infants.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* 18-45 y of age at the time of enrollment
* Pre-gravid or first trimester BMI 18.5 -40 kg/m2
* Uncomplicated singleton pregnancy
* Intention to exclusively breastfeed for \>3 months and, if parity \>1, that they successfully breastfed a previous pregnancy
* Term pregnancy (gest…
Inclusion Criteria:
* 18-45 y of age at the time of enrollment
* Pre-gravid or first trimester BMI 18.5 -40 kg/m2
* Uncomplicated singleton pregnancy
* Intention to exclusively breastfeed for \>3 months and, if parity \>1, that they successfully breastfed a previous pregnancy
* Term pregnancy (gestational age 37 to \<42 weeks)
* Infant with birth weight \>10th percentile of weight for gestational age
Exclusion Criteria:
* Any obstetric contra-indication to exercise at 1 month
* Diagnosis of uncontrolled (HbA1c \>7%) type 1 or type 2 diabetes, or gestational diabetes managed with insulin
* Intrauterine growth restriction
* Pre-eclampsia or other pregnancy complications
* Alcohol, cannabis or tobacco use
* Known congenital metabolic, endocrine disease, or congenital illness affecting infant feeding/growth
* Major fetal anomalies
* Musculoskeletal issues that would make exercise difficult
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