Obesity Trials / Trials in South Dakota
9 Recruiting Trials

Clinical Trials
for Obesity in South Dakota

9 clinical trials for Obesity are currently recruiting participants at study sites in South Dakota. Study-related care is provided at no cost.

9
Recruiting trials
6
Study sites
2
Cities
8
Industry-sponsored
8
Phase 3

Obesity clinical trials in South Dakota: what to expect

Obesity trials are among the most actively recruiting studies in the United States right now. Most test medicines from the GLP-1 family (the class that includes semaglutide and tirzepatide) or newer compounds that work on the same appetite and blood-sugar pathways, often in people who also have high blood pressure, sleep apnea, knee osteoarthritis or prediabetes. A smaller number study structured diet and exercise programs, devices, or weight-loss surgery.

In South Dakota, recruiting obesity studies are concentrated in Rapid City and Sioux Falls. 8 of the 9 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who obesity trials usually look for

Nearly every study sets a body mass index (BMI) threshold, most often 30 or higher, or 27 or higher when you also have a weight-related condition. Many ask that your weight has been stable for the last three months and that you are not currently using a prescription weight-loss drug. Age limits of 18 to 75 are common. Pregnancy, a history of pancreatitis or certain thyroid cancers, and bariatric surgery within the last few years are the exclusions that come up most.

If you have type 2 diabetes, look for trials that name it: some obesity studies exclude diabetes, while others are designed specifically for people who have both.

What taking part involves

A screening visit with a physical exam, blood work and an ECG usually comes first. Drug trials then run for six months to two years, with study visits every few weeks at the start and every one to three months later on. Most GLP-1 studies use a once-weekly injection you give yourself at home; many are placebo-controlled, meaning some participants receive an inactive version for part or all of the study, and you are told that before you agree to join. Study medication, visits and tests are provided at no cost, and most trials pay a stipend for time and travel.

Questions worth asking the study team

Whether there is a placebo group and how long it lasts; whether you can continue the medicine after the study ends; how many visits are required and how far the site is from you; and what happens if you need to stop early. Sites answer these every day and a ten-minute phone screen is the normal next step.

Showing 9 of 9 recruiting Obesity trials in South Dakota

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
PHASE3 Alexander City, Alabama +4 sites NCT07567001
This trial is looking for individuals with heart failure who are also obese. Participants will receive either an injection of NNC0487-0111 or a placebo once a week to see how well it works and how safe it is.
Recruiting
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
PHASE3 Anniston, Alabama +4 sites NCT07351045
This trial is looking for adults who are overweight or have obesity without type 2 diabetes. Participants will take a study drug or a placebo to help with weight management and will need to self-administer the treatment.
Recruiting
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
PHASE3 Guntersville, Alabama +4 sites NCT07351058
This trial is looking for people with obesity or overweight and type 2 diabetes. Participants will use an injectable medication to help with weight management.
Recruiting
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
PHASE3 Daphne, Alabama +4 sites NCT07037433
This trial is looking for adults with heart disease and obesity. Participants will receive either maridebart cafraglutide or a placebo while continuing usual care.
Recruiting
A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight
PHASE3 Escondido, California +4 sites NCT07253285
This trial is looking for children and teens aged 8 to 17 who have excess body weight. Participants will receive either a new drug or a placebo and will be followed for up to 4 years. There may be side effects from the treatments.
Recruiting
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
PHASE3 Birmingham, Alabama +4 sites NCT07037459
This trial is looking for adults with heart failure and obesity. Participants will take a new treatment along with their usual heart failure care to see if it helps reduce heart failure problems.
Recruiting
A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
PHASE3 Birmingham, Alabama +4 sites NCT07667803
This trial is looking for adults with obesity or overweight. Participants will take a medication called elecoglipron while following a diet and exercise program to help manage their weight.
Recruiting
A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee
PHASE3 Phoenix, Arizona +4 sites NCT07153471
This trial is looking for people who are 50 years or older and have osteoarthritis in their knee along with being overweight or obese. They should have tried to lose weight before but haven’t had success. However, if you've lost or gained more than 11 pounds recently, have diabetes, or a serious heart condition, you won’t be able to join.
Recruiting
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
N/A Sioux Falls, South Dakota +1 sites NCT01793168
This trial is looking for people who have a rare disease or are affected by a rare/uncommon condition. Participants will join a registry to help researchers connect and advance treatments for these rare diseases.
Recruiting
See all 9 Obesity trials in South Dakota

Where the Obesity studies are in South Dakota

Research sites running the most studies
  • Circle Clinical Research, Sioux Falls2 trials
  • Monument Health Clinical Research, Rapid City2 trials
  • Monument Health Clinical Rsrch, Rapid City2 trials
  • Care Access - Rapid City, Rapid City1 trial
  • Research Site, Rapid City1 trial
  • Sanford Health, Sioux Falls1 trial
By city

Counts are recruiting studies listing at least one site in South Dakota, from ClinicalTrials.gov, refreshed every two days.

Obesity clinical trials in South Dakota: common questions

How many Obesity clinical trials are recruiting in South Dakota?
TrialFinder currently lists 9 recruiting Obesity clinical trials with study sites in South Dakota. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Obesity clinical trials located in South Dakota?
Study sites for the Obesity trials listed on this page include Sioux Falls. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Obesity clinical trial in South Dakota?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Obesity trials in South Dakota also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Obesity clinical trial in South Dakota?
Each study sets its own criteria based on age, Obesity diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need a BMI over 30 to join an obesity clinical trial?
Most adult obesity trials require a BMI of 30 or higher, or 27 or higher if you also have a weight-related condition such as high blood pressure, prediabetes or sleep apnea. Each trial page lists its exact threshold.
Are obesity trial participants paid?
Study medication, visits and tests are provided free, and most obesity trials pay a stipend per visit for time and travel. The amount is set by each study and told to you before you enroll; it is never contingent on finishing the study.
Obesity Trials in Other States
Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware District of Columbia Florida Georgia Hawaii Idaho Illinois Indiana Iowa Kansas Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Mississippi Missouri Montana Nebraska Nevada New Hampshire New Jersey New Mexico New York North Carolina North Dakota Ohio Oklahoma Oregon Pennsylvania Rhode Island South Carolina Tennessee Texas Utah Vermont Virginia Washington West Virginia Wisconsin Wyoming
Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
All guides →

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About Obesity Trials

Obesity trials study GLP-1 receptor agonists, bariatric procedures, behavioural interventions, and combination weight-loss therapies in adults and adolescents.

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