35 Recruiting Trials

Clinical Trials
for Obesity in Colorado

35 clinical trials for Obesity are currently recruiting participants at study sites in Colorado. Study-related care is provided at no cost.

35
Recruiting trials
26
Study sites
7
Cities
14
Industry-sponsored
6
Phase 2
13
Phase 3

Obesity clinical trials in Colorado: what to expect

Obesity trials are among the most actively recruiting studies in the United States right now. Most test medicines from the GLP-1 family (the class that includes semaglutide and tirzepatide) or newer compounds that work on the same appetite and blood-sugar pathways, often in people who also have high blood pressure, sleep apnea, knee osteoarthritis or prediabetes. A smaller number study structured diet and exercise programs, devices, or weight-loss surgery.

In Colorado, recruiting obesity studies are concentrated in Aurora, Colorado Springs, Denver and Arvada, with sites in 3 other cities. 14 of the 35 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who obesity trials usually look for

Nearly every study sets a body mass index (BMI) threshold, most often 30 or higher, or 27 or higher when you also have a weight-related condition. Many ask that your weight has been stable for the last three months and that you are not currently using a prescription weight-loss drug. Age limits of 18 to 75 are common. Pregnancy, a history of pancreatitis or certain thyroid cancers, and bariatric surgery within the last few years are the exclusions that come up most.

If you have type 2 diabetes, look for trials that name it: some obesity studies exclude diabetes, while others are designed specifically for people who have both.

What taking part involves

A screening visit with a physical exam, blood work and an ECG usually comes first. Drug trials then run for six months to two years, with study visits every few weeks at the start and every one to three months later on. Most GLP-1 studies use a once-weekly injection you give yourself at home; many are placebo-controlled, meaning some participants receive an inactive version for part or all of the study, and you are told that before you agree to join. Study medication, visits and tests are provided at no cost, and most trials pay a stipend for time and travel.

Questions worth asking the study team

Whether there is a placebo group and how long it lasts; whether you can continue the medicine after the study ends; how many visits are required and how far the site is from you; and what happens if you need to stop early. Sites answer these every day and a ten-minute phone screen is the normal next step.

Showing 20 of 35 recruiting Obesity trials in Colorado

Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS)
PHASE3 Tucson, Arizona +4 sites NCT07817875
This trial is looking for children aged 6 to less than 12 years who have obesity. Participants will try a new treatment along with healthy lifestyle changes for about two years.
Recruiting
A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)
PHASE3 Tucson, Arizona +4 sites NCT06672549
This trial is looking for teens aged 12 to under 18 who are struggling with obesity or being overweight. Participants must have tried losing weight before but were unsuccessful.
Recruiting
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
PHASE3 Birmingham, Alabama +4 sites NCT07564414
This trial is looking for people with obesity, with or without type 2 diabetes, who want to lose weight. Participants will be assigned by chance to receive either CagriSema or semaglutide for about 83 weeks.
Recruiting
Efficacy and Safety of Ribupatide in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes
PHASE3 Anniston, Alabama +4 sites NCT07284875
This trial is looking for people who are overweight or living with obesity and have related health issues, but do not have diabetes. Participants will receive a weekly injection of ribupatide or a placebo to see how it affects their weight.
Recruiting
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
PHASE3 Alexander City, Alabama +4 sites NCT07567001
This trial is looking for individuals with heart failure who are also obese. Participants will receive either an injection of NNC0487-0111 or a placebo once a week to see how well it works and how safe it is.
Recruiting
Adipocyte-Derived Extracellular Vesicles, Weight Loss, and Endothelial Function
NA Boulder, Colorado NCT06776081
This trial is looking for adults aged 40 and older who are either underweight or overweight and have obesity. Participants will be evaluated for their fat tissue health and possible weight loss effects on blood vessel function.
Recruiting
A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)
PHASE3 Aurora, Colorado +4 sites NCT06760546
This trial is looking for patients aged 4 and older with congenital hypothalamic obesity. Participants will take a daily injection of Setmelanotide or a placebo for up to 26 weeks to assess its effects on weight, hunger, and quality of life.
Recruiting
Neuronal and Behavioral Effects of an Implicit Priming Approach to Improve Eating Behaviors in Obesity
NA Aurora, Colorado NCT05107908
This trial is looking for adults aged 18 to 65 who are overweight or have obesity. Participants will explore different ways to change their eating behaviors and how it affects their brain and body weight.
Recruiting
Physiologic Response to Bariatric Surgery and the Impact of Adjunct Semaglutide in Adolescents
PHASE1 Aurora, Colorado NCT06575738
This trial is looking for teenagers and young adults, ages 12 to 24, who are planning to have or have already had weight loss surgery. Participants will help researchers understand body changes after surgery and whether a medication can support weight loss.
Recruiting
HealthyTogether: RCT of a Dyadic Weight Management Intervention
NA Aurora, Colorado +1 sites NCT06619041
This trial is looking for Veterans who are overweight or obese and want to lose weight. Participants will join a 14-week virtual program with a support person like a family member or friend to help improve their weight and health habits.
Recruiting
Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) Signaling
NA Aurora, Colorado NCT06129110
This trial is looking for adults aged 18-70 who are overweight and do little to no exercise. Participants will follow a 12-week weight loss diet and undergo various health tests before and after the program.
Recruiting
Thermogenenic Responses to Fasting and Overfeeding in Women
NA Aurora, Colorado NCT06610162
This trial is looking for women to understand how menopause affects weight gain. Participants will fast for 24 hours and then eat extra calories to see how their bodies respond.
Recruiting
Exercise Effects on the Neurobiology Underlying Stress-related Eating Behaviors in Veterans
NA Aurora, Colorado NCT06627569
This trial is looking for veterans who are overweight and not physically active to study how exercise affects their brain responses to food. Participants will need to visit a site in Aurora, CO to take part in this research.
Recruiting
Snacking Effects on the Brain Response to Foods and Satiety During Dieting
NA Aurora, Colorado NCT07428187
This trial is looking for adults aged 25-45 who are overweight and willing to try daily snacks of walnuts or pretzels. Participants will help researchers understand how different snacks affect the brain while dieting.
Recruiting
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
PHASE3 Birmingham, Alabama +4 sites NCT07282600
This trial is looking for people with obesity or overweight who also have type 2 diabetes. Participants will take eloralintide or a placebo for about 75 weeks to see if it helps with weight loss.
Recruiting
A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight
PHASE3 Aurora, Colorado +4 sites NCT07369011
This trial is looking for people with obesity or overweight who have moderate-to-severe obstructive sleep apnea. Participants will be assigned to a group based on their current use of sleep apnea treatment and will be involved for about 76 weeks.
Recruiting
AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight
PHASE3 Anniston, Alabama +4 sites NCT07720271
This trial is looking for adults with excess body weight who want to lose weight. Participants will take either zenagamtide or a placebo as a daily tablet. Which one you get is chosen by chance.
Recruiting
Obesity, Metabolic Dysregulation and the Airway Epithelium in Asthmatics
NA Aurora, Colorado NCT03215836
This trial is looking for adults with asthma, obesity, and metabolic syndrome to study how these conditions affect airway health. Participants will undergo assessments related to their breathing and overall health.
Recruiting
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight
PHASE3 Mobile, Alabama +4 sites NCT07353931
This trial is looking for adults who are at least 50 years old and have knee pain from osteoarthritis, as well as being overweight or obese. It’s important that they haven't had a recent heart issue or surgery for weight loss, and they shouldn’t have diabetes. Participants also need to have tried losing weight through diet without success.
Recruiting
A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
PHASE3 Birmingham, Alabama +4 sites NCT07667803
This trial is looking for adults with obesity or overweight. Participants will take a medication called elecoglipron while following a diet and exercise program to help manage their weight.
Recruiting

Where the Obesity studies are in Colorado

  • University of Colorado Anschutz Medical Campus, Aurora6 trials
  • University of Colorado - Anschutz Medical Campus, Aurora3 trials
  • Care Access - Aurora, Aurora2 trials
  • Children's Hospital Colorado, Colorado Springs2 trials
  • Children's Hospital Colorado, Aurora2 trials
  • Rocky Mountain Regional VA Medical Center, Aurora, CO, Aurora2 trials

Counts are recruiting studies listing at least one site in Colorado, from ClinicalTrials.gov, refreshed every two days.

Obesity clinical trials in Colorado: common questions

How many Obesity clinical trials are recruiting in Colorado?
TrialFinder currently lists 35 recruiting Obesity clinical trials with study sites in Colorado. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Obesity clinical trials located in Colorado?
Study sites for the Obesity trials listed on this page include Boulder, Aurora. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Obesity clinical trial in Colorado?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Obesity trials in Colorado also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Obesity clinical trial in Colorado?
Each study sets its own criteria based on age, Obesity diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need a BMI over 30 to join an obesity clinical trial?
Most adult obesity trials require a BMI of 30 or higher, or 27 or higher if you also have a weight-related condition such as high blood pressure, prediabetes or sleep apnea. Each trial page lists its exact threshold.
Are obesity trial participants paid?
Study medication, visits and tests are provided free, and most obesity trials pay a stipend per visit for time and travel. The amount is set by each study and told to you before you enroll; it is never contingent on finishing the study.
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Obesity trials study GLP-1 receptor agonists, bariatric procedures, behavioural interventions, and combination weight-loss therapies in adults and adolescents.

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