Clinical Trials
for COPD in Colorado
16 clinical trials for COPD are currently recruiting participants at study sites in Colorado. Study-related care is provided at no cost.
COPD clinical trials in Colorado: what to expect
COPD trials test new inhaler combinations, biologic injections for people whose flare-ups continue despite inhalers, and treatments for the cough and mucus that come with chronic bronchitis. Others study pulmonary rehabilitation and exercise, valves and other procedures for emphysema, home oxygen and remote monitoring, and programs to stop smoking. Most enroll people with moderate to severe disease who still have symptoms on their current treatment.
In Colorado, recruiting copd studies are concentrated in Denver, Aurora, Lakewood and Boulder, with sites in 2 other cities. 9 of the 16 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.
Who COPD trials usually look for
Trials confirm COPD with a breathing test at screening and set a range for lung function, usually between 30 and 80 percent of predicted. Most ask for a smoking history of at least ten pack-years, though current smokers are generally accepted. Biologic trials require one or two flare-ups in the past year needing steroids or antibiotics and sometimes a blood eosinophil count above a threshold. Common exclusions are asthma as the main diagnosis, another significant lung disease and a flare-up in the past four weeks. Ages are usually 40 to 80.
What taking part involves
Screening includes spirometry, blood work and a symptom questionnaire, then a short run-in while you record symptoms. Drug trials run six to twelve months with visits every four to twelve weeks, breathing tests, a six-minute walk in some, and a diary or app. Your maintenance inhalers continue, sometimes replaced by study-supplied versions, and rescue inhaler is always allowed. Rehabilitation trials involve two or three sessions a week for eight to twelve weeks. Study care is free and visits are usually paid.
Questions worth asking the study team
Whether your inhalers stay the same; how breathing tests and walking tests are scheduled; the chance of placebo; what to do during a flare-up while enrolled; and whether oxygen users are accepted.
Showing 16 of 16 recruiting COPD trials in Colorado
Where the COPD studies are in Colorado
- National Jewish Health, Denver4 trials
- University of Colorado Anschutz Medical Campus, Aurora2 trials
- Alpine Clinical Research Center - Boulder - 47th Street- Site Number : 8400005, Boulder1 trial
- Critical Care Pulmonary & Sleep Associates- Site Number : 8400081, Lakewood1 trial
- GSK Investigational Site, Aurora1 trial
- GSK Investigational Site, Lakewood1 trial
Counts are recruiting studies listing at least one site in Colorado, from ClinicalTrials.gov, refreshed every two days.
COPD clinical trials in Colorado: common questions
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