Brenipatide for Moderate-to-Severe COPD

A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)

Recruiting Phase 2 Interventional Study
Pulmonary Disease, Chronic Obstructive
Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
40 – 75
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
606 (estimated)
Sponsor
Eli Lilly and Company · Industry
Who this trial is looking for

This trial is looking for adults with moderate-to-severe COPD to test a new treatment called Brenipatide. Participants will receive either the treatment or a placebo and will be monitored for about one year.

Are You a Good Fit for This Trial?
Must be taking LABALAMAICS

You may be able to join if

  • I have been diagnosed with COPD for at least 12 months.
  • I am a current or former smoker with a smoking history of at least 10 pack-years.
  • I have moderate-to-severe COPD.
  • I have a mMRC Dyspnea Scale grade of 2 or higher.
  • I have had 2 or more moderate or 1 severe COPD flare-ups in the past year.
  • I have been on stable COPD treatment for at least one month before the trial.

You may not be able to join if

  • I have a known serious lung condition other than COPD.
  • I have had a recent active infection before the trial.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial

The main purpose of this study is to assess if different dose levels of Brenipatide are safe and work the way they are intended to work in participants with moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD), when compared with placebo. The study will last approximately one year.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Have a physician diagnosis of Chronic Obstructive Pulmonary Disease (COPD), at least 12 months prior to screening who meet the following criteria: * Current or former smokers with a smoking history of greater than or equal to (≥) 10 pack-years * Moderate-to-severe COPD (p…
Contacts

Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or

1-317-615-4559

LillyTrials@Lilly.com

CONTACT

Physicians interested in becoming principal investigators please contact

clinical_inquiry_hub@lilly.com

CONTACT