COPD Trials / Trials in Ohio
18 Recruiting Trials

Clinical Trials
for COPD in Ohio

18 clinical trials for COPD are currently recruiting participants at study sites in Ohio. Study-related care is provided at no cost.

18
Recruiting trials
24
Study sites
9
Cities
13
Industry-sponsored
5
Phase 2
6
Phase 3

COPD clinical trials in Ohio: what to expect

COPD trials test new inhaler combinations, biologic injections for people whose flare-ups continue despite inhalers, and treatments for the cough and mucus that come with chronic bronchitis. Others study pulmonary rehabilitation and exercise, valves and other procedures for emphysema, home oxygen and remote monitoring, and programs to stop smoking. Most enroll people with moderate to severe disease who still have symptoms on their current treatment.

In Ohio, recruiting copd studies are concentrated in Cleveland, Columbus, Toledo and Cincinnati, with sites in 5 other cities. 13 of the 18 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who COPD trials usually look for

Trials confirm COPD with a breathing test at screening and set a range for lung function, usually between 30 and 80 percent of predicted. Most ask for a smoking history of at least ten pack-years, though current smokers are generally accepted. Biologic trials require one or two flare-ups in the past year needing steroids or antibiotics and sometimes a blood eosinophil count above a threshold. Common exclusions are asthma as the main diagnosis, another significant lung disease and a flare-up in the past four weeks. Ages are usually 40 to 80.

What taking part involves

Screening includes spirometry, blood work and a symptom questionnaire, then a short run-in while you record symptoms. Drug trials run six to twelve months with visits every four to twelve weeks, breathing tests, a six-minute walk in some, and a diary or app. Your maintenance inhalers continue, sometimes replaced by study-supplied versions, and rescue inhaler is always allowed. Rehabilitation trials involve two or three sessions a week for eight to twelve weeks. Study care is free and visits are usually paid.

Questions worth asking the study team

Whether your inhalers stay the same; how breathing tests and walking tests are scheduled; the chance of placebo; what to do during a flare-up while enrolled; and whether oxygen users are accepted.

Showing 18 of 18 recruiting COPD trials in Ohio

Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD
NA Columbus, Ohio +4 sites NCT07051707
This trial is looking for adults with chronic obstructive pulmonary disease (COPD) who have been receiving standard medical care. Participants will undergo a one-time procedure to help improve their breathing.
Recruiting
Implementation of a Sarcopenia Clinic to Diagnose and Treat Skeletal Muscle Loss Due to COPD
NA Cleveland, Ohio NCT07059637
This trial is looking for patients with COPD who have muscle loss. Participants will receive specialized care from a team of healthcare professionals to help improve their muscle strength and overall health.
Recruiting
myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home
NA Birmingham, Alabama +4 sites NCT05204888
This trial is looking for people with moderate to very severe COPD who have had a recent severe worsening of their condition. Participants will use the myAirvo 3 device at home while receiving their usual COPD care for at least one year.
Recruiting
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)
PHASE3 Foley, Alabama +4 sites NCT06883305
This trial is looking for adults with moderate to very severe COPD. Participants will be required to take part in assessments and treatments involving Tezepelumab.
Recruiting
Multi-Center Clean Air Randomized Controlled Trial in COPD
PHASE3 Birmingham, Alabama +4 sites NCT06376994
This trial is looking for people with chronic obstructive pulmonary disease (COPD) to see if using an air cleaner can help them. Participants will be asked questions about their health and will have an air cleaner placed in their home to test its effectiveness.
Recruiting
To Evaluate the Effect of EXPD-101/FXS7553 Compared With Placebo in Patients With COPD Over 52 Weeks of Treatment
PHASE2 Phoenix, Arizona +4 sites NCT07684820
This trial is looking for people with chronic obstructive pulmonary disease (COPD) who have had recent flare-ups of their condition. Participants will take either the study drug or a placebo every day for a year.
Recruiting
The Study of Chronic Obstructive Pulmonary Disease (COPD) Participants Treated With Dupilumab (STRIDE) Registry
N/A Columbus, Ohio +4 sites NCT07612878
This trial is looking for people with Chronic Obstructive Pulmonary Disease (COPD) who are starting treatment with dupilumab. Participants will share their experiences and health information to help assess the treatment's effectiveness and safety.
Recruiting
Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3
NA Birmingham, Alabama +4 sites NCT06891755
This trial is looking for adults with COPD and emphysema who experience difficulty breathing. Participants will receive a device to help open their airways and will be followed for three years.
Recruiting
PEP Buddy in Pulmonary Rehabilitation
NA Cincinnati, Ohio +1 sites NCT07404826
This trial is looking for Veterans with COPD who are going to Pulmonary Rehabilitation. Participants will use a special device that might help with breathing and exercise during their treatment.
Recruiting
A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease
PHASE3 Athens, Alabama +4 sites NCT06283966
This trial is looking for adults aged 40 to 80 with Chronic Obstructive Pulmonary Disease (COPD). Participants will receive a combination inhaler treatment and attend study visits for assessments.
Recruiting
A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
PHASE2 Birmingham, Alabama +4 sites NCT07082738
This trial is looking for people with moderate to very severe COPD to test the effects of a new drug called AZD6793. Participants will take AZD6793 or a placebo and help researchers learn about its safety and effectiveness.
Recruiting
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype
PHASE3 Chandler, Arizona +4 sites NCT07190209
This trial is looking for adults aged 40 to 80 with chronic obstructive pulmonary disease (COPD) that isn't well controlled. Participants will receive either lunsekimig or a placebo for approximately 48 weeks, followed by an 8-week follow-up.
Recruiting
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype
PHASE3 Birmingham, Alabama +4 sites NCT07190222
This trial is looking for adults aged 40 to 80 with chronic obstructive pulmonary disease (COPD) that is not well controlled. Participants will receive either lunsekimig or a placebo for about 48 weeks, followed by an 8-week follow-up.
Recruiting
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease
PHASE2 Birmingham, Alabama +4 sites NCT07363694
This trial is looking for adults aged 35 to 80 with moderate to severe COPD. Participants will receive either the study medicine PF-07275315 or a placebo through shots over 24 to 68 weeks and will attend multiple clinic visits during this time.
Recruiting
Trial Comparing the Safety and Efficacy of Two Different Oral VPV Doses With Placebo as Treatment for RV in Participants With COPD
PHASE2 Mobile, Alabama +4 sites NCT07610395
This trial is looking for people with COPD who have had recent respiratory infections. Participants will take a medication called vapendavir to see if it helps reduce their cold symptoms.
Recruiting
A Study of 24 to 52 Weeks Treatment to Evaluate The Efficacy And Safety of Galvokimig in Study Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD) With Chronic Bronchitis
PHASE2 Columbus, Ohio +4 sites NCT07725939
This trial is looking for adults aged 40 to 80 with moderate-to-severe chronic obstructive pulmonary disease (COPD) and chronic bronchitis. Participants will take a medication called galvokimig and be monitored for breathing issues over several months.
Recruiting
PRagmatic EVAluation of a Quality Improvement Program for People Living With Modifiable High-risk COPD.
NA Cleveland, Ohio +2 sites NCT05306743
This trial is looking for primary care teams to participate in a quality improvement program for patients with chronic obstructive pulmonary disease (COPD). Teams will either receive the program or usual care and will help evaluate the program's effects over three years.
Recruiting
An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema
NA Phoenix, Arizona +4 sites NCT06035120
This trial is looking for people aged 40 to 80 with severe emphysema who have certain breathing issues. Participants will receive a treatment called AeriSeal Foam and may have a valve placed to help improve lung function, with follow-up for two years.
Recruiting
See all 18 COPD trials in Ohio

Where the COPD studies are in Ohio

Research sites running the most studies
  • Cleveland Clinic Foundation, Cleveland3 trials
  • Research Site, Cleveland2 trials
  • Research Site, Columbus2 trials
  • Research Site, Marion2 trials
  • Asthma & Allergy Center - Toledo- Site Number : 8400110, Toledo1 trial
  • Cincinnati VA Medical Center, Cincinnati1 trial
By city

Counts are recruiting studies listing at least one site in Ohio, from ClinicalTrials.gov, refreshed every two days.

COPD clinical trials in Ohio: common questions

How many COPD clinical trials are recruiting in Ohio?
TrialFinder currently lists 18 recruiting COPD clinical trials with study sites in Ohio. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are COPD clinical trials located in Ohio?
Study sites for the COPD trials listed on this page include Columbus, Cleveland, Cincinnati. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a COPD clinical trial in Ohio?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many COPD trials in Ohio also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a COPD clinical trial in Ohio?
Each study sets its own criteria based on age, COPD diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need to quit smoking to join a COPD trial?
Most COPD trials accept current smokers; some require that you have stopped, and smoking-cessation trials are specifically for people who still smoke. The listing states the rule.
What tests confirm COPD for a trial?
Spirometry, a breathing test done at the site before and after a bronchodilator, which gives the lung function figure trials use to set their range. You do not need recent results to ask.
Will I keep using my inhalers during a trial?
Yes. Trials add the study treatment to your maintenance inhalers or supply a standardized equivalent, and a rescue inhaler is always permitted.
COPD Trials in Other States
Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware District of Columbia Florida Georgia Hawaii Idaho Illinois Indiana Iowa Kansas Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Mississippi Missouri Montana Nebraska Nevada New Hampshire New Jersey New Mexico New York North Carolina North Dakota Oklahoma Oregon Pennsylvania Rhode Island South Carolina South Dakota Tennessee Texas Utah Vermont Virginia Washington West Virginia Wisconsin Wyoming
Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
All guides →

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About COPD Trials

COPD trials investigate bronchodilators, anti-inflammatory biologics, pulmonary rehabilitation, and lung-volume reduction procedures for chronic obstructive lung disease.

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