Multiple Sclerosis Trials / Trials in Oklahoma
6 Recruiting Trials

Clinical Trials
for Multiple Sclerosis in Oklahoma

6 clinical trials for Multiple Sclerosis are currently recruiting participants at study sites in Oklahoma. Study-related care is provided at no cost.

6
Recruiting trials
5
Study sites
2
Cities
4
Industry-sponsored
1
Phase 2
2
Phase 3

Multiple Sclerosis clinical trials in Oklahoma: what to expect

Multiple sclerosis trials divide into relapsing and progressive forms. Relapsing MS studies test new oral and infused disease-modifying therapies, usually against an approved medicine rather than a placebo. Progressive MS has fewer approved options, so trials there test drugs meant to slow disability, protect nerves or repair myelin, and often do use a placebo. Alongside these are trials of rehabilitation, exercise, diet, fatigue and bladder treatments, and studies that simply follow people over time with MRI and blood tests.

In Oklahoma, recruiting multiple sclerosis studies are concentrated in Oklahoma City and Norman. 4 of the 6 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who multiple sclerosis trials usually look for

Listings state the type of MS, an age range (commonly 18 to 55 for relapsing trials, up to 65 for progressive) and a disability score range measured by the study neurologist. Relapsing trials usually want a relapse or new MRI activity in the past one to two years. Drug trials require a washout from your current therapy, which varies from weeks to months by drug and is managed by the site. Symptom and rehabilitation trials let you stay on your treatment.

What taking part involves

Screening includes a neurological exam, blood work and an MRI. Drug trials then run one to three years with visits every one to three months, an MRI every six to twelve months and a relapse assessment whenever symptoms change. Relapses are treated as normal. The study drug, scans and visits are free, and an extension usually lets everyone continue the active treatment afterwards. Rehabilitation trials involve sessions over eight to twenty-four weeks with walking, hand and cognition tests.

Questions worth asking the study team

What the comparison treatment is; how the washout from your current therapy is handled and how long it lasts; how many MRIs are needed; whether there is an extension; and what happens if you relapse during the study.

Showing 6 of 6 recruiting Multiple Sclerosis trials in Oklahoma

A Study to Investigate Multiple Sclerosis Relapse Prevention With mRNA-1195 Compared With Placebo in Participants Aged 18 to ≤55 Years
PHASE2 Oklahoma City, Oklahoma +4 sites NCT06735248
This trial is looking for people aged 18 to 55 with multiple sclerosis. Participants will receive either the study drug, mRNA-1195, or a placebo while being monitored for safety and side effects.
Recruiting
A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)
N/A Birmingham, Alabama +4 sites NCT06433752
This trial is looking for people with a confirmed diagnosis of relapsing multiple sclerosis who are starting treatment with BRIUMVI®. Participants will receive the medication and share their experiences and results during the study.
Recruiting
A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis
PHASE3 Phoenix, Arizona +4 sites NCT07299019
This trial is looking for people with Secondary Progressive Multiple Sclerosis who have not had a clinical relapse for at least 2 years. Participants will receive either orelabrutinib or a placebo for 1 to 5 years.
Recruiting
Early Versus Delayed Start of Ocrevus Zunovo for Relapsing Multiple Sclerosis
N/A Oklahoma City, Oklahoma NCT07878923
This trial is looking for adults with relapsing multiple sclerosis to see if starting a treatment called Ocrevus Zunovo soon after a relapse can help reduce future relapses. Participants will receive injections and have regular check-ups over 18 months.
Recruiting
Skeletal Muscle Aging and Responsiveness in Aged People With MS
NA Oklahoma City, Oklahoma NCT07500727
This trial is looking for older adults (60+) with Multiple Sclerosis. Participants will engage in an exercise program over approximately 4 months, attending about 3 sessions each week.
Recruiting
Study to Evaluate Safety, Efficacy and Pharmacokinetics (PK) of a Modified Regimen of Ublituximab
PHASE3 Birmingham, Alabama +4 sites NCT05877963
This trial is looking for people with relapsing multiple sclerosis. Participants will receive a modified treatment of ublituximab and help researchers understand its effectiveness and safety.
Recruiting
See all 6 Multiple Sclerosis trials in Oklahoma

Where the Multiple Sclerosis studies are in Oklahoma

Research sites running the most studies
  • Oklahoma Medical Research Foundation, Oklahoma City2 trials
  • OMRF Multiple Sclerosis Center of Excellence, Oklahoma City1 trial
  • Oklahoma Medical Research Foundation (OMRF) MS Center of Excellence, Oklahoma City1 trial
  • TG Therapeutics Investigational Trial Site, Norman1 trial
  • TG Therapeutics Investigational Trial Site, Oklahoma City1 trial
By city

Counts are recruiting studies listing at least one site in Oklahoma, from ClinicalTrials.gov, refreshed every two days.

Multiple Sclerosis clinical trials in Oklahoma: common questions

How many Multiple Sclerosis clinical trials are recruiting in Oklahoma?
TrialFinder currently lists 6 recruiting Multiple Sclerosis clinical trials with study sites in Oklahoma. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Multiple Sclerosis clinical trials located in Oklahoma?
Study sites for the Multiple Sclerosis trials listed on this page include Oklahoma City. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Multiple Sclerosis clinical trial in Oklahoma?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Multiple Sclerosis trials in Oklahoma also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Multiple Sclerosis clinical trial in Oklahoma?
Each study sets its own criteria based on age, Multiple Sclerosis diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Will I get a placebo instead of MS treatment?
In relapsing MS almost never: trials compare the new drug with an approved medicine, so everyone is treated. Progressive MS trials more often use a placebo because fewer approved treatments exist, and an extension usually follows.
Do I need to stop my current MS medicine to join?
For a drug trial, yes, after a washout that depends on your current medicine and is supervised by the study neurologist. Trials of rehabilitation, diet or symptom treatments let you continue it.
What is an EDSS score?
The Expanded Disability Status Scale, a 0 to 10 score a neurologist assigns from an exam, mostly based on walking. Trials set a range, and the study neurologist scores you at screening; you do not need to know it in advance.
Multiple Sclerosis Trials in Other States
Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware District of Columbia Florida Georgia Hawaii Idaho Illinois Indiana Iowa Kansas Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Mississippi Missouri Montana Nebraska Nevada New Hampshire New Jersey New Mexico New York North Carolina North Dakota Ohio Oregon Pennsylvania Rhode Island South Carolina South Dakota Tennessee Texas Utah Vermont Virginia Washington West Virginia Wisconsin Wyoming
Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
All guides →

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About Multiple Sclerosis Trials

MS trials investigate disease-modifying therapies, remyelination strategies, stem-cell transplants, and neuroprotective agents for relapsing and progressive forms of MS.

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