Exercise Program for Older Adults with Multiple Sclerosis

Skeletal Muscle Aging and Responsiveness in Aged People With MS

Recruiting N/A Interventional Study
Multiple Sclerosis Aging
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
60 and older
Sex
Any
Study type
Interventional
Purpose
Other
Participants needed
10 (estimated)
Sponsor
Oklahoma Medical Research Foundation · Other
Who this trial is looking for

This trial is looking for older adults (60+) with Multiple Sclerosis. Participants will engage in an exercise program over approximately 4 months, attending about 3 sessions each week.

Are You a Good Fit for This Trial?
Must not be taking MetforminHigh dose statins
Rules you out Chronic kidney diseaseAlzheimer's diseaseCurrent cancer diagnosisCerebrovascular disease

You may be able to join if

  • I am 60 years old or older
  • I have been diagnosed with Multiple Sclerosis
  • I do not have unmanaged chronic diseases other than MS
  • I have not been part of a structured exercise program in the last 6 months
  • I am able to provide informed consent
  • I have an EDSS score between 2 and 5.5

You may not be able to join if

  • I have a neuromuscular or musculoskeletal disorder affecting exercise
  • I have a cardiopulmonary disorder or breathing issues
  • I have metabolic diseases like liver disease or type 2 diabetes
  • I take metformin or any insulin-sensitizing drugs
  • I have another disease that could affect my exercise response
  • I have a history of chemotherapy in the last 5 years
  • I have a lidocaine allergy
  • I use tobacco or consume excessive alcohol

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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About This Trial
The purposes of this study are to: 1) compare baseline muscle and cardiovascular health in older individuals (\>60 years old) diagnosed with MS to age-matched people without MS, 2) determine muscle and whole body changes to an exercise training program, 3) determine if the muscle in a more affected leg in individuals diagnosed with MS is different from the muscle of a less affected leg, and 4) if …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * 1\. Male or female aged 60 or above 2. Free of unmanaged chronic diseases other than multiple sclerosis 3. No structured exercise program (2 or more bouts/wk) within previous 6 months 4. Cognitively capable of providing informed consent 5. Must meet EDSS score between 2 to 5.5…
Contacts

Lena Fuentes

4052717745

lena-fuentes@omrf.org

CONTACT

Bobbette Miller

4052714214

bobbette-miller@ou.edu

CONTACT