mRNA-1195 for Preventing Multiple Sclerosis Relapses

A Study to Investigate Multiple Sclerosis Relapse Prevention With mRNA-1195 Compared With Placebo in Participants Aged 18 to ≤55 Years

Recruiting Phase 2 Interventional Study
Multiple Sclerosis
Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 55
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
180 (estimated)
Sponsor
ModernaTX, Inc. · Industry
Who this trial is looking for

This trial is looking for people aged 18 to 55 with multiple sclerosis. Participants will receive either the study drug, mRNA-1195, or a placebo while being monitored for safety and side effects.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am between 18 and 55 years old.
  • I have multiple sclerosis and have been stable for at least 30 days.
  • I am Epstein-Barr virus (EBV)-seropositive.
  • I can use effective contraception if I can become pregnant.
  • I am medically stable as confirmed by a doctor.

You may not be able to join if

  • I have a fever over 100.4°F in the past 72 hours.
  • I have unstable medical conditions that affect my safety.
  • I received any vaccine for COVID-19 within 28 days of starting the study.
  • I have a history of myocarditis, pericarditis, or myopericarditis.
  • I have received any strong immune suppressants in the last 30 days.
  • I plan to donate blood within 28 days after the study injection.
  • I have had any history of drug or alcohol abuse.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer a few quick questions to see if you may meet the eligibility requirements.

Check Your Eligibility
About This Trial

The primary objective of this trial is to evaluate the safety and reactogenicity of mRNA-1195 in participants with multiple sclerosis.

Trial Locations
Loading…

Loading trial locations…

Eligibility Criteria
Inclusion Criteria: * Medically stable as determined by Investigator's medical evaluation, which will include assessment of medical history, physical examination, laboratory testing, and review of any previously conducted cardiac monitoring. * Participants who are Epstein-Barr virus (EBV)-seroposit…
Contacts

Moderna WeCare Team

1-866-663-3762

WeCareClinicalTrials@modernatx.com

CONTACT