Stroke Trials / Trials in Florida
49 Recruiting Trials

Clinical Trials
for Stroke in Florida

49 clinical trials for Stroke are currently recruiting participants at study sites in Florida. Study-related care is provided at no cost.

49
Recruiting trials
74
Study sites
28
Cities
20
Industry-sponsored
4
Phase 2
8
Phase 3

Stroke clinical trials in Florida: what to expect

Stroke trials come in three kinds. Acute treatment trials enroll within hours of a stroke, inside the hospital, and are not something you apply to. Recovery and rehabilitation trials enroll from a few weeks to many years after a stroke and test intensive therapy, robotics, brain and nerve stimulation, virtual reality and medicines meant to help the brain rewire. Prevention trials test blood thinners, cholesterol and blood pressure treatments and procedures to lower the chance of a second stroke.

In Florida, recruiting stroke studies are concentrated in Jacksonville, Tampa, Miami and Gainesville, with sites in 24 other cities. 20 of the 49 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who stroke trials usually look for

Listings state the time since stroke, the type (a clot or a bleed) and the kind of difficulty they study, such as arm and hand weakness, walking, speech or vision, often with a range on a standard scale that the study therapist scores. Many recovery trials enroll people six months or more after their stroke, so an older stroke does not rule you out. Prevention trials look for a stroke or mini-stroke in a recent window plus a specific risk factor such as atrial fibrillation. Most require that you can give consent and take part in sessions.

What taking part involves

Rehabilitation trials are intensive: several sessions a week for four to twelve weeks, with assessments by a therapist before, after and some months later, and sometimes an MRI. The comparison group often receives standard therapy or the same program later. Prevention trials are long and light: a study medicine or placebo added to usual care, visits every few months for several years. Study care and equipment are free and travel is usually reimbursed; a family member is welcome at visits.

Questions worth asking the study team

How many sessions are required and where; whether a comparison group receives the therapy later; whether current rehabilitation can continue; what the assessments involve; and whether transport can be arranged.

Showing 20 of 49 recruiting Stroke trials in Florida

Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)
PHASE2 Fairhope, Alabama +4 sites NCT05065216
This trial is looking for adults who have had a moderate stroke and present within 24 hours of the onset. Participants will receive a study medication to see if it helps improve their condition.
Recruiting
Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Exosome Intranasal Instillations for Stroke
PHASE1 Naples, Florida +1 sites NCT05158101
This trial is looking for people diagnosed with stroke to test a new treatment using stem cell exosomes. Participants will receive this treatment through their nose and will need to sign a consent form to join.
Recruiting
Telerehabilitation In The Home After Stroke
NA Downey, California +4 sites NCT06682429
This trial is looking for people who have arm weakness from a stroke that happened 90 to 150 days ago. Participants will receive telerehabilitation to improve their arm function, alongside usual care, for 6 weeks.
Recruiting
Safety and Efficacy of NeuroTechR3 System for Upper Extremity Recovery After Stroke
NA Jacksonville, Florida NCT07769281
This trial is looking for people who have had a stroke and want to improve their arm function. Participants will use the NeuroTechR3 System to help with upper extremity training.
Recruiting
GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study
NA Tucson, Arizona +4 sites NCT03821129
This trial is looking for patients who have had a recent stroke and also have a condition called Patent Foramen Ovale (PFO). Participants will receive a device to help reduce the risk of future strokes.
Recruiting
Pilot/Pivotal Study of DBS+Rehab After Stroke
NA Jacksonville, Florida +4 sites NCT05701280
This trial is looking for people who had a stroke and still have weakness in their arm. Participants will receive treatment to help improve their arm function.
Recruiting
RESPARK - Brain Q for Chronic Stroke
NA Jacksonville, Florida NCT07095920
This trial is looking for adults with chronic stroke to test a new treatment that helps brain recovery after a stroke. Participants will use a wearable device and engage in physical exercises during the study.
Recruiting
Responses to Backward Walking Training Post-Stroke
NA Gainesville, Florida +1 sites NCT04928482
This trial is looking for veterans who have had a stroke and want to improve their walking and balance. Participants will take part in training sessions focused on backward walking and undergo brain activity scans before and after the training.
Recruiting
Treatment With Endovascular Intervention for STroke Patients With Existing Disability
N/A Birmingham, Alabama +4 sites NCT05911568
This trial is looking for adults who had a stroke and have moderate to severe disability before it. Participants will compare two treatment options: a procedure to remove blood clots or regular medical care without the procedure.
Recruiting
Diagnostic Performance Study of the EMVision Emu™ Brain Scanner in the Detection of Intracranial Hemorrhage in Suspected Stroke Patients
N/A Jacksonville, Florida +4 sites NCT06999122
This trial is looking for adults suspected of having a stroke. Participants will undergo a scan with a new device designed to quickly detect bleeding in the brain.
Recruiting
Stroke Thrombectomy and Aneurysm Registry
N/A Birmingham, Alabama +4 sites NCT04994756
This trial is looking for patients undergoing surgery for brain injuries. Participants will help collect information about their treatment and outcomes.
Recruiting
Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial
PHASE3 Mobile, Alabama +4 sites NCT05611242
This trial is looking for adults aged 18 to 79 who have had an acute ischemic stroke. Participants will receive a specific treatment for blocked arteries in the brain to see if it's more effective than other approaches.
Recruiting
Optimizing Reperfusion to Improve Outcomes and Neurologic Function
PHASE2 Long Beach, California +4 sites NCT06990867
This trial is looking for adults with acute ischemic stroke who seek care within 4.5 to 24 hours. Participants will receive either a new treatment called JX10 or a placebo to see how it affects recovery and safety.
Recruiting
Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke
PHASE3 Sarasota, Florida +4 sites NCT05691244
This trial is looking for adults who have had an acute ischemic stroke. Participants will receive a new treatment called sovateltide along with standard care and will be monitored for safety and effectiveness.
Recruiting
Strategy for Improving Stroke Treatment Response
PHASE2 Birmingham, Alabama +4 sites NCT05948566
This trial is looking for adults who have had a suspected ischemic stroke. Participants will receive a treatment called TS23 to see how safe and effective it is within a specific time after their stroke.
Recruiting
Study of BB-031 in Acute Ischemic Stroke Patients (RAISE)
PHASE2 Scottsdale, Arizona +4 sites NCT06226805
This trial is looking for adults who have had an acute ischemic stroke within the last 24 hours. Participants will receive either the study drug or a placebo and will be monitored for 90 days.
Recruiting
WE-TRUST (Workflow Optimization to Reduce Time to Endovascular Reperfusion for Ultra-fast Stroke Treatment)
NA Jacksonville, Florida +4 sites NCT04701684
This trial is looking for adults who have had a stroke and can get to a stroke center quickly. Participants will receive treatment aimed at improving outcomes for stroke patients.
Recruiting
Balloon Guide Versus Conventional Guide Catheter in Stroke Thrombectomy
NA Tampa, Florida +1 sites NCT07085390
Recruiting
The Pivotal Study of RapidPulseTM Aspiration System
NA Jacksonville, Florida +4 sites NCT06029491
This trial is looking for adults aged 18 to 80 who have had a stroke within the last 8 hours. Participants will receive a treatment to remove a blood clot in the brain and will be monitored for 90 days.
Recruiting
Hospital Implementation of a Stroke Protocol for Emergency Evaluation and Disposition
NA Miami, Florida +4 sites NCT06094478
This trial is looking for adult patients who have experienced a stroke. It aims to find better ways for hospitals to quickly assess and transfer patients needing advanced treatment for their stroke.
Recruiting
See all 49 Stroke trials in Florida

Where the Stroke studies are in Florida

Research sites running the most studies
  • University of South Florida, Tampa8 trials
  • Jackson Memorial Hospital, Miami6 trials
  • Baptist Health Research Institute, Jacksonville3 trials
  • Brooks Rehabilitation, Jacksonville3 trials
  • Mayo Clinic, Jacksonville3 trials
  • Sarasota Memorial Hospital, Sarasota3 trials
By city

Counts are recruiting studies listing at least one site in Florida, from ClinicalTrials.gov, refreshed every two days.

Stroke clinical trials in Florida: common questions

How many Stroke clinical trials are recruiting in Florida?
TrialFinder currently lists 49 recruiting Stroke clinical trials with study sites in Florida. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Stroke clinical trials located in Florida?
Study sites for the Stroke trials listed on this page include Naples, Jacksonville, Gainesville, Sarasota, Tampa, Miami. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Stroke clinical trial in Florida?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Stroke trials in Florida also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Stroke clinical trial in Florida?
Each study sets its own criteria based on age, Stroke diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
My stroke was years ago. Are there still trials for me?
Yes. Many recovery trials enroll people six months or more after a stroke, and some accept strokes from many years earlier, because they study whether therapy can still improve movement or speech.
What are stroke rehabilitation trials like?
Intensive and hands-on: therapy sessions several times a week for one to three months, sometimes with a device or stimulation added, and assessments before and after. The comparison group usually gets standard therapy or the program at a later date.
Can a family member join a trial if they cannot consent for themselves?
Some trials allow a legally authorized representative to consent on a participant's behalf, particularly acute and prevention studies; most rehabilitation trials need the participant's own consent and active participation. Ask the study team.
Stroke Trials in Other States
Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware District of Columbia Georgia Hawaii Idaho Illinois Indiana Iowa Kansas Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Mississippi Missouri Montana Nebraska Nevada New Hampshire New Jersey New Mexico New York North Carolina North Dakota Ohio Oklahoma Oregon Pennsylvania Rhode Island South Carolina South Dakota Tennessee Texas Utah Vermont Virginia Washington West Virginia Wisconsin Wyoming
Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
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About Stroke Trials

Stroke trials cover thrombolytic agents, mechanical thrombectomy techniques, neuroprotective drugs, and intensive rehabilitation programmes for acute and chronic stroke.

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