Stroke Trials / Trials in Michigan
28 Recruiting Trials

Clinical Trials
for Stroke in Michigan

28 clinical trials for Stroke are currently recruiting participants at study sites in Michigan. Study-related care is provided at no cost.

28
Recruiting trials
28
Study sites
13
Cities
9
Industry-sponsored
3
Phase 2
8
Phase 3

Stroke clinical trials in Michigan: what to expect

Stroke trials come in three kinds. Acute treatment trials enroll within hours of a stroke, inside the hospital, and are not something you apply to. Recovery and rehabilitation trials enroll from a few weeks to many years after a stroke and test intensive therapy, robotics, brain and nerve stimulation, virtual reality and medicines meant to help the brain rewire. Prevention trials test blood thinners, cholesterol and blood pressure treatments and procedures to lower the chance of a second stroke.

In Michigan, recruiting stroke studies are concentrated in Ann Arbor, Detroit, Wyoming and Flint, with sites in 9 other cities. 9 of the 28 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who stroke trials usually look for

Listings state the time since stroke, the type (a clot or a bleed) and the kind of difficulty they study, such as arm and hand weakness, walking, speech or vision, often with a range on a standard scale that the study therapist scores. Many recovery trials enroll people six months or more after their stroke, so an older stroke does not rule you out. Prevention trials look for a stroke or mini-stroke in a recent window plus a specific risk factor such as atrial fibrillation. Most require that you can give consent and take part in sessions.

What taking part involves

Rehabilitation trials are intensive: several sessions a week for four to twelve weeks, with assessments by a therapist before, after and some months later, and sometimes an MRI. The comparison group often receives standard therapy or the same program later. Prevention trials are long and light: a study medicine or placebo added to usual care, visits every few months for several years. Study care and equipment are free and travel is usually reimbursed; a family member is welcome at visits.

Questions worth asking the study team

How many sessions are required and where; whether a comparison group receives the therapy later; whether current rehabilitation can continue; what the assessments involve; and whether transport can be arranged.

Showing 20 of 28 recruiting Stroke trials in Michigan

Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)
PHASE2 Fairhope, Alabama +4 sites NCT05065216
This trial is looking for adults who have had a moderate stroke and present within 24 hours of the onset. Participants will receive a study medication to see if it helps improve their condition.
Recruiting
Telerehabilitation for Post-Stroke Hand Function
NA Ann Arbor, Michigan NCT07792655
This trial is looking for adults with chronic stroke who need help improving their hand function. Participants will receive either guided hand training at home using technology or a standard home exercise program.
Recruiting
Telerehabilitation In The Home After Stroke
NA Downey, California +4 sites NCT06682429
This trial is looking for people who have arm weakness from a stroke that happened 90 to 150 days ago. Participants will receive telerehabilitation to improve their arm function, alongside usual care, for 6 weeks.
Recruiting
GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study
NA Tucson, Arizona +4 sites NCT03821129
This trial is looking for patients who have had a recent stroke and also have a condition called Patent Foramen Ovale (PFO). Participants will receive a device to help reduce the risk of future strokes.
Recruiting
Passive Robots for Stroke Rehabilitation: A Feasibility Study
NA Ann Arbor, Michigan NCT07218276
This trial is looking for adults aged 18 to 75 who have had a stroke. Participants will use new devices and treatments to help with arm rehabilitation after their stroke.
Recruiting
Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials
N/A Birmingham, Alabama +4 sites NCT05338697
This trial is looking for adults who have had a stroke and are experiencing motor difficulties in one arm. Participants will undergo specific tests and procedures to help researchers understand recovery outcomes.
Recruiting
Stroke Thrombectomy and Aneurysm Registry
N/A Birmingham, Alabama +4 sites NCT04994756
This trial is looking for patients undergoing surgery for brain injuries. Participants will help collect information about their treatment and outcomes.
Recruiting
Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial
PHASE3 Mobile, Alabama +4 sites NCT05611242
This trial is looking for adults aged 18 to 79 who have had an acute ischemic stroke. Participants will receive a specific treatment for blocked arteries in the brain to see if it's more effective than other approaches.
Recruiting
Optimizing Reperfusion to Improve Outcomes and Neurologic Function
PHASE2 Long Beach, California +4 sites NCT06990867
This trial is looking for adults with acute ischemic stroke who seek care within 4.5 to 24 hours. Participants will receive either a new treatment called JX10 or a placebo to see how it affects recovery and safety.
Recruiting
Study of BB-031 in Acute Ischemic Stroke Patients (RAISE)
PHASE2 Scottsdale, Arizona +4 sites NCT06226805
This trial is looking for adults who have had an acute ischemic stroke within the last 24 hours. Participants will receive either the study drug or a placebo and will be monitored for 90 days.
Recruiting
Hospital Implementation of a Stroke Protocol for Emergency Evaluation and Disposition
NA Ann Arbor, Michigan +4 sites NCT06094478
This trial is looking for adult patients who have experienced a stroke. It aims to find better ways for hospitals to quickly assess and transfer patients needing advanced treatment for their stroke.
Recruiting
Delay AvoIding Primary Evaluation for ThRombectomy of Acute StrokE Patients With Large Vessel OCclusion in the Angiography SuiTe
NA Detroit, Michigan +4 sites NCT06825897
This trial is looking for adults with suspected acute stroke caused by a blockage in a large blood vessel. Participants will either go directly to a special imaging room or first be seen in the emergency department to find out which approach helps them recover better.
Recruiting
Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY
N/A Phoenix, Arizona +4 sites NCT04916210
This trial is looking for adults who have had a stroke and want to help researchers learn more about how strokes affect thinking and memory. Participants will undergo evaluations to understand their recovery and brain health after a stroke.
Recruiting
REal-world Clinical evAulation of Medtronic NeurOVascular Products for Acute Ischemic Stroke (RECANOVA Registry)
N/A Flint, Michigan +2 sites NCT07599904
Recruiting
Cognition and Imaging With Tigertriever
N/A Grand Rapids, Michigan +4 sites NCT05531461
This trial is looking for people who had a certain type of stroke and were treated with a device called Tigertriever. Participants will help researchers understand if using this device improves thinking skills after the stroke.
Recruiting
Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging
N/A Birmingham, Alabama +4 sites NCT05907629
This trial is looking for people who have recently had a stroke caused by narrowing of blood vessels in the brain. Participants will undergo an MRI to help researchers learn more about treatment options for this condition.
Recruiting
Brain Stimulation Effects on Post-Stroke Fatigue and Aphasia
NA Ann Arbor, Michigan +1 sites NCT07151677
Recruiting
Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable
PHASE3 Dothan, Alabama +4 sites NCT07430956
This trial is looking for adults with atrial fibrillation who are unable or choose not to take blood thinners. Participants will take one of two study drugs to see how well they help prevent strokes and blood clots.
Recruiting
Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation
PHASE3 Alexander City, Alabama +4 sites NCT07626411
This trial is looking for adults with atrial fibrillation who need treatment to prevent strokes. Participants will receive either the study drug REGN7508 or another medication called apixaban.
Recruiting
Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial - Part 2
PHASE3 Birmingham, Alabama +4 sites NCT07227246
This trial is looking for adults who have experienced a type of stroke called intracerebral hemorrhage. Participants may receive a treatment called rFVIIa within a specific time frame to see if it improves their recovery.
Recruiting
See all 28 Stroke trials in Michigan

Where the Stroke studies are in Michigan

Research sites running the most studies
  • University of Michigan, Ann Arbor9 trials
  • Henry Ford Hospital, Detroit4 trials
  • University of Michigan Health-West, Wyoming3 trials
  • Henry Ford Health System, Detroit2 trials
  • McLaren Flint, Flint2 trials
  • McLaren Macomb, Mount Clemens2 trials
By city

Counts are recruiting studies listing at least one site in Michigan, from ClinicalTrials.gov, refreshed every two days.

Stroke clinical trials in Michigan: common questions

How many Stroke clinical trials are recruiting in Michigan?
TrialFinder currently lists 28 recruiting Stroke clinical trials with study sites in Michigan. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Stroke clinical trials located in Michigan?
Study sites for the Stroke trials listed on this page include Ann Arbor, Detroit, Flint, Grand Rapids. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Stroke clinical trial in Michigan?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Stroke trials in Michigan also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Stroke clinical trial in Michigan?
Each study sets its own criteria based on age, Stroke diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
My stroke was years ago. Are there still trials for me?
Yes. Many recovery trials enroll people six months or more after a stroke, and some accept strokes from many years earlier, because they study whether therapy can still improve movement or speech.
What are stroke rehabilitation trials like?
Intensive and hands-on: therapy sessions several times a week for one to three months, sometimes with a device or stimulation added, and assessments before and after. The comparison group usually gets standard therapy or the program at a later date.
Can a family member join a trial if they cannot consent for themselves?
Some trials allow a legally authorized representative to consent on a participant's behalf, particularly acute and prevention studies; most rehabilitation trials need the participant's own consent and active participation. Ask the study team.
Stroke Trials in Other States
Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware District of Columbia Florida Georgia Hawaii Idaho Illinois Indiana Iowa Kansas Kentucky Louisiana Maine Maryland Massachusetts Minnesota Mississippi Missouri Montana Nebraska Nevada New Hampshire New Jersey New Mexico New York North Carolina North Dakota Ohio Oklahoma Oregon Pennsylvania Rhode Island South Carolina South Dakota Tennessee Texas Utah Vermont Virginia Washington West Virginia Wisconsin Wyoming
Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
All guides →

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About Stroke Trials

Stroke trials cover thrombolytic agents, mechanical thrombectomy techniques, neuroprotective drugs, and intensive rehabilitation programmes for acute and chronic stroke.

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