No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
40 – 75
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
22 (estimated)
Sponsor
University of Michigan · Other
Who this trial is looking for
This trial is looking for adults with chronic stroke who need help improving their hand function. Participants will receive either guided hand training at home using technology or a standard home exercise program.
Are You a Good Fit for This Trial?
You may be able to join if
I have had a stroke affecting one side of my body.
I have had my stroke for at least 6 months.
I have a Mini Mental State Examination score of 22 or higher.
You may not be able to join if
I have had a cerebellar stroke.
I have an unstable heart condition.
I have uncontrolled diabetes or hypertension.
I have had a recent injury or fracture in my arms.
I have a history of serious orthopedic or neurological issues.
I have joint contractures or significant spasticity in my hand.
I am pregnant or planning to become pregnant.
I cannot communicate or provide consent.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
This pilot randomized controlled trial will evaluate the feasibility and preliminary effects of a home-based, technology-enabled hand telerehabilitation program for adults with chronic stroke. Participants will receive either remotely guided hand training or a standard home exercise program matched for duration and intensity. Outcomes will include measures of hand function, adherence, and feasibil…
This pilot randomized controlled trial will evaluate the feasibility and preliminary effects of a home-based, technology-enabled hand telerehabilitation program for adults with chronic stroke. Participants will receive either remotely guided hand training or a standard home exercise program matched for duration and intensity. Outcomes will include measures of hand function, adherence, and feasibility to assess the potential of telerehabilitation for improving access to structured post-stroke hand rehabilitation.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Unilateral cortical or subcortical stroke
* Chronic stroke (≥ 6 months since stroke)
* No significant cognitive deficits as determined by the Mini Mental State Examination (MMSE) score (score≥ 22)
Exclusion Criteria:
* Cerebellar stroke
* Unstable heart condition, uncontroll…
Inclusion Criteria:
* Unilateral cortical or subcortical stroke
* Chronic stroke (≥ 6 months since stroke)
* No significant cognitive deficits as determined by the Mini Mental State Examination (MMSE) score (score≥ 22)
Exclusion Criteria:
* Cerebellar stroke
* Unstable heart condition, uncontrolled diabetes or hypertension
* Recent trauma or fracture in the upper extremities
* History of significant orthopedic or neurological conditions that could affect hand function (e.g., multiple sclerosis)
* Recent history of significant spatial neglect
* Joint contractures or significant spasticity in the hand
* History of a recent Botulinum Toxin (Botox) injection to the upper-extremity muscles (≤ 3 months)
* Pregnant or actively planning to become pregnant (self-reported)
* Inability to communicate or unable to consent
Exclusion Criteria for subjects exposed to Transcranial Magnetic Stimulation (TMS):
* Unable to obtain reliable motor evoked potentials
* Recent history of repeated fainting spells or syncope.
* Recent history of seizure while on anti-seizure medication
* Recent history of skull fracture/head injury
* Ferromagnetic metal implants in the skull
* Cochlear implant
* Implanted deep brain stimulator
* Implanted vagus nerve stimulator
* Implanted cervical spine epidural stimulator
* Ventriculoperitoneal shunt
* Skull defect related to the current stroke
* Previous serious adverse reaction to TMS
* Implanted electronic cardiac device (e.g., cardiac pacemaker)
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