19 Recruiting Trials

Clinical Trials
for Stroke in Minnesota

19 clinical trials for Stroke are currently recruiting participants at study sites in Minnesota. Study-related care is provided at no cost.

19
Recruiting trials
22
Study sites
8
Cities
5
Industry-sponsored
2
Phase 2
4
Phase 3

Stroke clinical trials in Minnesota: what to expect

Stroke trials come in three kinds. Acute treatment trials enroll within hours of a stroke, inside the hospital, and are not something you apply to. Recovery and rehabilitation trials enroll from a few weeks to many years after a stroke and test intensive therapy, robotics, brain and nerve stimulation, virtual reality and medicines meant to help the brain rewire. Prevention trials test blood thinners, cholesterol and blood pressure treatments and procedures to lower the chance of a second stroke.

In Minnesota, recruiting stroke studies are concentrated in Minneapolis, Rochester, Edina and Burnsville, with sites in 4 other cities. 5 of the 19 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who stroke trials usually look for

Listings state the time since stroke, the type (a clot or a bleed) and the kind of difficulty they study, such as arm and hand weakness, walking, speech or vision, often with a range on a standard scale that the study therapist scores. Many recovery trials enroll people six months or more after their stroke, so an older stroke does not rule you out. Prevention trials look for a stroke or mini-stroke in a recent window plus a specific risk factor such as atrial fibrillation. Most require that you can give consent and take part in sessions.

What taking part involves

Rehabilitation trials are intensive: several sessions a week for four to twelve weeks, with assessments by a therapist before, after and some months later, and sometimes an MRI. The comparison group often receives standard therapy or the same program later. Prevention trials are long and light: a study medicine or placebo added to usual care, visits every few months for several years. Study care and equipment are free and travel is usually reimbursed; a family member is welcome at visits.

Questions worth asking the study team

How many sessions are required and where; whether a comparison group receives the therapy later; whether current rehabilitation can continue; what the assessments involve; and whether transport can be arranged.

Showing 19 of 19 recruiting Stroke trials in Minnesota

Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)
PHASE2 Fairhope, Alabama +4 sites NCT05065216
This trial is looking for adults who have had a moderate stroke and present within 24 hours of the onset. Participants will receive a study medication to see if it helps improve their condition.
Recruiting
GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study
NA Tucson, Arizona +4 sites NCT03821129
This trial is looking for patients who have had a recent stroke and also have a condition called Patent Foramen Ovale (PFO). Participants will receive a device to help reduce the risk of future strokes.
Recruiting
Pilot/Pivotal Study of DBS+Rehab After Stroke
NA Rochester, Minnesota +4 sites NCT05701280
This trial is looking for people who had a stroke and still have weakness in their arm. Participants will receive treatment to help improve their arm function.
Recruiting
Feasibility of a Remotely Delivered Step Count Intervention in Chronic Stroke
NA Minneapolis, Minnesota NCT07649135
This trial is looking for people who have had a stroke at least 6 months ago. Participants will join 6 sessions over 6 weeks with an occupational therapist and track their steps.
Recruiting
Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials
N/A Birmingham, Alabama +4 sites NCT05338697
This trial is looking for adults who have had a stroke and are experiencing motor difficulties in one arm. Participants will undergo specific tests and procedures to help researchers understand recovery outcomes.
Recruiting
Stroke Thrombectomy and Aneurysm Registry
N/A Birmingham, Alabama +4 sites NCT04994756
This trial is looking for patients undergoing surgery for brain injuries. Participants will help collect information about their treatment and outcomes.
Recruiting
Strategy for Improving Stroke Treatment Response
PHASE2 Birmingham, Alabama +4 sites NCT05948566
This trial is looking for adults who have had a suspected ischemic stroke. Participants will receive a treatment called TS23 to see how safe and effective it is within a specific time after their stroke.
Recruiting
A Study Of Vagus Nerve Stimulation (VNS) With Mobility Training For Gait Recovery After Chronic Ischemic Stroke
NA Rochester, Minnesota NCT07291024
This trial is looking for adults who have had an ischemic stroke at least 6 months ago and have difficulty walking. Participants will receive vagus nerve stimulation along with mobility training to help improve their walking abilities.
Recruiting
StrokeNet Thrombectomy Endovascular Platform
NA Birmingham, Alabama +4 sites NCT06289985
This trial is looking for people who have had a suspected ischemic stroke due to a blockage in a large or medium blood vessel in the brain. Participants will be assessed to determine if they can receive a treatment called endovascular thrombectomy.
Recruiting
Continuous Dual Aspiration Technique With Zoom System for Stroke
N/A Huntsville, Alabama +4 sites NCT07491952
This trial is looking for adults who have had an ischemic stroke. Participants will undergo a specific type of thrombectomy procedure using a new technique.
Recruiting
Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY
N/A Phoenix, Arizona +4 sites NCT04916210
This trial is looking for adults who have had a stroke and want to help researchers learn more about how strokes affect thinking and memory. Participants will undergo evaluations to understand their recovery and brain health after a stroke.
Recruiting
Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging
N/A Birmingham, Alabama +4 sites NCT05907629
This trial is looking for people who have recently had a stroke caused by narrowing of blood vessels in the brain. Participants will undergo an MRI to help researchers learn more about treatment options for this condition.
Recruiting
Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial - Part 2
PHASE3 Birmingham, Alabama +4 sites NCT07227246
This trial is looking for adults who have experienced a type of stroke called intracerebral hemorrhage. Participants may receive a treatment called rFVIIa within a specific time frame to see if it improves their recovery.
Recruiting
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery
PHASE3 Birmingham, Alabama +4 sites NCT03907046
This trial is looking for adults who have had a recent brain bleed and have atrial fibrillation. Participants will compare the effects of a medication called apixaban with aspirin to see which better prevents strokes or death.
Recruiting
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
PHASE3 Little Rock, Arkansas +4 sites NCT04045665
This trial is looking for patients who develop new atrial fibrillation after heart bypass surgery. Participants will receive a treatment to help prevent blood clots while monitoring their safety and health.
Recruiting
Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage
N/A Irvine, California +4 sites NCT06402968
This trial is looking for adults who have high blood pressure after a stroke. Participants will receive either clevidipine or another treatment to help manage their blood pressure within 60 minutes.
Recruiting
Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future
N/A Rochester, Minnesota +4 sites NCT06039176
This trial is looking for adults who are scheduled to receive a HeartMate 3® device to assist their heart. Participants will help researchers understand how the device data relates to their quality of life and health conditions.
Recruiting
CTSN Embolic Protection Trial
NA North Little Rock, Arkansas +4 sites NCT06027788
This trial is looking for patients aged 60 and older who are scheduled for certain types of heart valve surgeries. By participating, I would be helping to test a device designed to protect the heart during the procedure.
Recruiting
The Fourth Left Atrial Appendage Occlusion Study
NA Birmingham, Alabama +4 sites NCT05963698
This trial is looking for people with atrial fibrillation who are at high risk of stroke, even while taking blood thinners. Participants will undergo a procedure to block a specific part of the heart to see if it helps prevent strokes.
Recruiting

Where the Stroke studies are in Minnesota

  • Mayo Clinic, Rochester6 trials
  • M Health Fairview University of Minnesota Medical Center, Minneapolis4 trials
  • M Health Fairview Southdale Hospital, Edina3 trials
  • Abbott Northwestern Hospital, Minneapolis2 trials
  • Mayo Clinic Saint Marys Campus, Rochester2 trials
  • Allina Health, Minneapolis1 trial

Counts are recruiting studies listing at least one site in Minnesota, from ClinicalTrials.gov, refreshed every two days.

Stroke clinical trials in Minnesota: common questions

How many Stroke clinical trials are recruiting in Minnesota?
TrialFinder currently lists 19 recruiting Stroke clinical trials with study sites in Minnesota. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Stroke clinical trials located in Minnesota?
Study sites for the Stroke trials listed on this page include Rochester, Minneapolis. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Stroke clinical trial in Minnesota?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Stroke trials in Minnesota also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Stroke clinical trial in Minnesota?
Each study sets its own criteria based on age, Stroke diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
My stroke was years ago. Are there still trials for me?
Yes. Many recovery trials enroll people six months or more after a stroke, and some accept strokes from many years earlier, because they study whether therapy can still improve movement or speech.
What are stroke rehabilitation trials like?
Intensive and hands-on: therapy sessions several times a week for one to three months, sometimes with a device or stimulation added, and assessments before and after. The comparison group usually gets standard therapy or the program at a later date.
Can a family member join a trial if they cannot consent for themselves?
Some trials allow a legally authorized representative to consent on a participant's behalf, particularly acute and prevention studies; most rehabilitation trials need the participant's own consent and active participation. Ask the study team.
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Stroke trials cover thrombolytic agents, mechanical thrombectomy techniques, neuroprotective drugs, and intensive rehabilitation programmes for acute and chronic stroke.

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