Vagus Nerve Stimulation with Mobility Training for Stroke

A Study Of Vagus Nerve Stimulation (VNS) With Mobility Training For Gait Recovery After Chronic Ischemic Stroke

Recruiting N/A Interventional Study
Ischemic Stroke
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
20 (estimated)
Sponsor
Mayo Clinic · Other
Who this trial is looking for

This trial is looking for adults who have had an ischemic stroke at least 6 months ago and have difficulty walking. Participants will receive vagus nerve stimulation along with mobility training to help improve their walking abilities.

Are You a Good Fit for This Trial?
Rules you out Parkinson's diseaseAmyotrophic Lateral Sclerosis (ALS)Multiple Sclerosis (MS)dementiamajor head trauma

You may be able to join if

  • I am at least 18 years old.
  • I have had an ischemic stroke over 6 months ago.
  • I have trouble walking, with a gait speed of less than 0.8 m/s on a 10-meter walk test.
  • I can provide informed consent.

You may not be able to join if

  • I have had an intracerebral hemorrhage.
  • I have had active or prior psychosis or substance abuse in the last two years.
  • Before my stroke, my modified Rankin Scale (mRS) score was 3 to 5.
  • I am unable to participate in in-clinic rehabilitation.
  • I have a preexisting neurological disorder that affects my walking, like Parkinson's disease or dementia.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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About This Trial

The purpose of this study is to evaluate the safety, feasibility, and efficacy of vagus nerve stimulation (VNS) paired with mobility training to improve lower extremity function and gait in individuals with chronic ischemic stroke.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age ≥ 18 years * Ischemic stroke ≥6 months prior to enrollment. * Post-stroke lower extremity impairment defined as gait velocity of less than 0.8 m/s on a 10-meter walk test * Provision of informed consent Exclusion Criteria: * Intracerebral Hemorrhage * Active or prior psy…
Contacts

Neurosurgery Research Team

507-538-6563

heaser.olyvia@mayo.edu

CONTACT