Stroke Trials / Trials in Alabama
18 Recruiting Trials

Clinical Trials
for Stroke in Alabama

18 clinical trials for Stroke are currently recruiting participants at study sites in Alabama. Study-related care is provided at no cost.

18
Recruiting trials
12
Study sites
6
Cities
5
Industry-sponsored
2
Phase 2
6
Phase 3

Stroke clinical trials in Alabama: what to expect

Stroke trials come in three kinds. Acute treatment trials enroll within hours of a stroke, inside the hospital, and are not something you apply to. Recovery and rehabilitation trials enroll from a few weeks to many years after a stroke and test intensive therapy, robotics, brain and nerve stimulation, virtual reality and medicines meant to help the brain rewire. Prevention trials test blood thinners, cholesterol and blood pressure treatments and procedures to lower the chance of a second stroke.

In Alabama, recruiting stroke studies are concentrated in Birmingham, Dothan, Fairhope and Mobile, with sites in 2 other cities. 5 of the 18 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who stroke trials usually look for

Listings state the time since stroke, the type (a clot or a bleed) and the kind of difficulty they study, such as arm and hand weakness, walking, speech or vision, often with a range on a standard scale that the study therapist scores. Many recovery trials enroll people six months or more after their stroke, so an older stroke does not rule you out. Prevention trials look for a stroke or mini-stroke in a recent window plus a specific risk factor such as atrial fibrillation. Most require that you can give consent and take part in sessions.

What taking part involves

Rehabilitation trials are intensive: several sessions a week for four to twelve weeks, with assessments by a therapist before, after and some months later, and sometimes an MRI. The comparison group often receives standard therapy or the same program later. Prevention trials are long and light: a study medicine or placebo added to usual care, visits every few months for several years. Study care and equipment are free and travel is usually reimbursed; a family member is welcome at visits.

Questions worth asking the study team

How many sessions are required and where; whether a comparison group receives the therapy later; whether current rehabilitation can continue; what the assessments involve; and whether transport can be arranged.

Showing 18 of 18 recruiting Stroke trials in Alabama

Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)
PHASE2 Fairhope, Alabama +4 sites NCT05065216
This trial is looking for adults who have had a moderate stroke and present within 24 hours of the onset. Participants will receive a study medication to see if it helps improve their condition.
Recruiting
Pharmacogenomics in Stroke: Feasibility of CYP2C19 Testing
NA Birmingham, Alabama NCT06943586
This trial is looking for patients who have had a minor stroke or are at high risk for a transient ischemic attack (TIA) and are currently in the hospital. Participants will undergo genetic testing to help doctors decide on the best medications during their hospital stay.
Recruiting
Treatment With Endovascular Intervention for STroke Patients With Existing Disability
N/A Birmingham, Alabama +4 sites NCT05911568
This trial is looking for adults who had a stroke and have moderate to severe disability before it. Participants will compare two treatment options: a procedure to remove blood clots or regular medical care without the procedure.
Recruiting
Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials
N/A Birmingham, Alabama +4 sites NCT05338697
This trial is looking for adults who have had a stroke and are experiencing motor difficulties in one arm. Participants will undergo specific tests and procedures to help researchers understand recovery outcomes.
Recruiting
Stroke Thrombectomy and Aneurysm Registry
N/A Birmingham, Alabama +4 sites NCT04994756
This trial is looking for patients undergoing surgery for brain injuries. Participants will help collect information about their treatment and outcomes.
Recruiting
Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial
PHASE3 Mobile, Alabama +4 sites NCT05611242
This trial is looking for adults aged 18 to 79 who have had an acute ischemic stroke. Participants will receive a specific treatment for blocked arteries in the brain to see if it's more effective than other approaches.
Recruiting
Strategy for Improving Stroke Treatment Response
PHASE2 Birmingham, Alabama +4 sites NCT05948566
This trial is looking for adults who have had a suspected ischemic stroke. Participants will receive a treatment called TS23 to see how safe and effective it is within a specific time after their stroke.
Recruiting
StrokeNet Thrombectomy Endovascular Platform
NA Birmingham, Alabama +4 sites NCT06289985
This trial is looking for people who have had a suspected ischemic stroke due to a blockage in a large or medium blood vessel in the brain. Participants will be assessed to determine if they can receive a treatment called endovascular thrombectomy.
Recruiting
Continuous Dual Aspiration Technique With Zoom System for Stroke
N/A Huntsville, Alabama +4 sites NCT07491952
This trial is looking for adults who have had an ischemic stroke. Participants will undergo a specific type of thrombectomy procedure using a new technique.
Recruiting
Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging
N/A Birmingham, Alabama +4 sites NCT05907629
This trial is looking for people who have recently had a stroke caused by narrowing of blood vessels in the brain. Participants will undergo an MRI to help researchers learn more about treatment options for this condition.
Recruiting
Rapid Evacuation and Access of Cerebral Hemorrhage Trial
NA Birmingham, Alabama +4 sites NCT06870812
This trial is looking for adults with a specific type of brain bleed to compare surgery with standard medical care. Participants will receive either surgery to remove blood from the brain or regular medical treatment.
Recruiting
Constraint-Induced Movement Therapy Plus Sensory Components After Stroke
NA Birmingham, Alabama NCT05515237
This trial is looking for people who have had a stroke at least 6 months ago and have difficulty using their affected arm. Participants will receive intense therapy aimed at improving the use of their weaker arm through specific exercises and techniques.
Recruiting
Constraint-Induced Movement Therapy for Adults Post-Stroke With Mild Upper Extremity Impairment
NA Birmingham, Alabama NCT05492513
This trial is looking for adults who had a stroke at least 6 months ago and have some movement ability in their affected arm. Participants will take part in daily therapy sessions focused on improving the use of their weaker hand.
Recruiting
Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable
PHASE3 Dothan, Alabama +4 sites NCT07430956
This trial is looking for adults with atrial fibrillation who are unable or choose not to take blood thinners. Participants will take one of two study drugs to see how well they help prevent strokes and blood clots.
Recruiting
Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation
PHASE3 Alexander City, Alabama +4 sites NCT07626411
This trial is looking for adults with atrial fibrillation who need treatment to prevent strokes. Participants will receive either the study drug REGN7508 or another medication called apixaban.
Recruiting
Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial - Part 2
PHASE3 Birmingham, Alabama +4 sites NCT07227246
This trial is looking for adults who have experienced a type of stroke called intracerebral hemorrhage. Participants may receive a treatment called rFVIIa within a specific time frame to see if it improves their recovery.
Recruiting
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery
PHASE3 Birmingham, Alabama +4 sites NCT03907046
This trial is looking for adults who have had a recent brain bleed and have atrial fibrillation. Participants will compare the effects of a medication called apixaban with aspirin to see which better prevents strokes or death.
Recruiting
The Fourth Left Atrial Appendage Occlusion Study
NA Birmingham, Alabama +4 sites NCT05963698
This trial is looking for people with atrial fibrillation who are at high risk of stroke, even while taking blood thinners. Participants will undergo a procedure to block a specific part of the heart to see if it helps prevent strokes.
Recruiting
See all 18 Stroke trials in Alabama

Where the Stroke studies are in Alabama

Research sites running the most studies
  • University of Alabama at Birmingham, Birmingham6 trials
  • University of Alabama Hospital, Birmingham5 trials
  • SEC Clinical Research, Dothan2 trials
  • Advanced Cardiovascular, Alexander City1 trial
  • Affinity Hospital dba Grandview Medical Center, Birmingham1 trial
  • Birmingham VA Medical Center, Birmingham1 trial
By city

Counts are recruiting studies listing at least one site in Alabama, from ClinicalTrials.gov, refreshed every two days.

Stroke clinical trials in Alabama: common questions

How many Stroke clinical trials are recruiting in Alabama?
TrialFinder currently lists 18 recruiting Stroke clinical trials with study sites in Alabama. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Stroke clinical trials located in Alabama?
Study sites for the Stroke trials listed on this page include Fairhope, Birmingham, Mobile, Huntsville, Dothan, Alexander City. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Stroke clinical trial in Alabama?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Stroke trials in Alabama also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Stroke clinical trial in Alabama?
Each study sets its own criteria based on age, Stroke diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
My stroke was years ago. Are there still trials for me?
Yes. Many recovery trials enroll people six months or more after a stroke, and some accept strokes from many years earlier, because they study whether therapy can still improve movement or speech.
What are stroke rehabilitation trials like?
Intensive and hands-on: therapy sessions several times a week for one to three months, sometimes with a device or stimulation added, and assessments before and after. The comparison group usually gets standard therapy or the program at a later date.
Can a family member join a trial if they cannot consent for themselves?
Some trials allow a legally authorized representative to consent on a participant's behalf, particularly acute and prevention studies; most rehabilitation trials need the participant's own consent and active participation. Ask the study team.
Stroke Trials in Other States
Alaska Arizona Arkansas California Colorado Connecticut Delaware District of Columbia Florida Georgia Hawaii Idaho Illinois Indiana Iowa Kansas Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Mississippi Missouri Montana Nebraska Nevada New Hampshire New Jersey New Mexico New York North Carolina North Dakota Ohio Oklahoma Oregon Pennsylvania Rhode Island South Carolina South Dakota Tennessee Texas Utah Vermont Virginia Washington West Virginia Wisconsin Wyoming
Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
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About Stroke Trials

Stroke trials cover thrombolytic agents, mechanical thrombectomy techniques, neuroprotective drugs, and intensive rehabilitation programmes for acute and chronic stroke.

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