MRI Study for Patients with Intracranial Stenosis and Stroke
Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging
Recruiting
Observational Study
Stroke
Intracranial Atherosclerotic Stenosis (ICAS)
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 300 (estimated)
- Sponsor
- Yale University · Other
Who this trial is looking for
This trial is looking for people who have recently had a stroke caused by narrowing of blood vessels in the brain. Participants will undergo an MRI to help researchers learn more about treatment options for this condition.
Are You a Good Fit for This Trial?
You may be able to join if
- I had a stroke within the last 30 days
- I have narrowing of my brain's blood vessels by 70-99%
- I am enrolled in the CAPTIVA trial
- I can have an MRI within 14 days of enrolling
You may not be able to join if
- I cannot have an MRI
- I am allergic to gadolinium contrast
- I have kidney disease with a low eGFR
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
CAPTIVA-MRI is an observational multimodal MR imaging study that is ancillary to the CAPTIVA trial \[a 3-arm, double-blind Phase III trial conducted at approximately 115 StrokeNet sites randomizing patients with stroke attributed to 70-99% intracranial atherosclerotic stenosis (ICAS) to aspirin plus ticagrelor, clopidogrel, or rivaroxaban.\] The primary goal of this ancillary study is to determine…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Enrollment in the CAPTIVA trial: nondisabling symptomatic ischemic infarct stroke within 30 days secondary to 70-99% stenosis of the intracranial ICA, MCA, BA or VA
* Ability to obtain baseline study MRI within 14 days of CAPTIVA enrollmen
Exclusion Criteria:
* Unable or unw…
Contacts