19 Recruiting Trials

Clinical Trials
for Stroke in Wisconsin

19 clinical trials for Stroke are currently recruiting participants at study sites in Wisconsin. Study-related care is provided at no cost.

19
Recruiting trials
15
Study sites
3
Cities
4
Industry-sponsored
2
Phase 2
2
Phase 3

Stroke clinical trials in Wisconsin: what to expect

Stroke trials come in three kinds. Acute treatment trials enroll within hours of a stroke, inside the hospital, and are not something you apply to. Recovery and rehabilitation trials enroll from a few weeks to many years after a stroke and test intensive therapy, robotics, brain and nerve stimulation, virtual reality and medicines meant to help the brain rewire. Prevention trials test blood thinners, cholesterol and blood pressure treatments and procedures to lower the chance of a second stroke.

In Wisconsin, recruiting stroke studies are concentrated in Milwaukee, Madison and Oneida. 4 of the 19 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who stroke trials usually look for

Listings state the time since stroke, the type (a clot or a bleed) and the kind of difficulty they study, such as arm and hand weakness, walking, speech or vision, often with a range on a standard scale that the study therapist scores. Many recovery trials enroll people six months or more after their stroke, so an older stroke does not rule you out. Prevention trials look for a stroke or mini-stroke in a recent window plus a specific risk factor such as atrial fibrillation. Most require that you can give consent and take part in sessions.

What taking part involves

Rehabilitation trials are intensive: several sessions a week for four to twelve weeks, with assessments by a therapist before, after and some months later, and sometimes an MRI. The comparison group often receives standard therapy or the same program later. Prevention trials are long and light: a study medicine or placebo added to usual care, visits every few months for several years. Study care and equipment are free and travel is usually reimbursed; a family member is welcome at visits.

Questions worth asking the study team

How many sessions are required and where; whether a comparison group receives the therapy later; whether current rehabilitation can continue; what the assessments involve; and whether transport can be arranged.

Showing 19 of 19 recruiting Stroke trials in Wisconsin

A Closed Loop Neural Activity Triggered Stroke Rehabilitation Device
NA Madison, Wisconsin NCT02098265
This trial is looking for stroke patients to test two brain stimulation techniques aimed at improving recovery. Participants will either have arm movement difficulties or be healthy individuals.
Recruiting
GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study
NA Tucson, Arizona +4 sites NCT03821129
This trial is looking for patients who have had a recent stroke and also have a condition called Patent Foramen Ovale (PFO). Participants will receive a device to help reduce the risk of future strokes.
Recruiting
Transcranial Alternating Current Stimulation (tACS) for the Recovery of Phonological Short-Term Memory in Patients With Aphasia After Stroke
NA Milwaukee, Wisconsin NCT06048159
This trial is looking for people who have had a stroke affecting the left side of their brain and are experiencing difficulties with language. Participants will receive a type of brain stimulation to see if it helps them recover their language skills.
Recruiting
Use of Sensory Substitution to Improve Arm Control After Stroke
NA Milwaukee, Wisconsin NCT03298243
This trial is looking for stroke survivors who want to improve their arm control. Participants will use a special device that provides vibrations to help with movement tasks, like reaching and drinking from a glass.
Recruiting
Blood Flow Regulation and Neuromuscular Function Post-Stroke
NA Milwaukee, Wisconsin +1 sites NCT06027294
This trial is looking for adults who have had a stroke at least 6 months ago. Participants will help researchers understand how blood flow affects muscle fatigue during exercise and try a simple non-invasive treatment to improve blood flow.
Recruiting
Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials
N/A Birmingham, Alabama +4 sites NCT05338697
This trial is looking for adults who have had a stroke and are experiencing motor difficulties in one arm. Participants will undergo specific tests and procedures to help researchers understand recovery outcomes.
Recruiting
Strategy for Improving Stroke Treatment Response
PHASE2 Birmingham, Alabama +4 sites NCT05948566
This trial is looking for adults who have had a suspected ischemic stroke. Participants will receive a treatment called TS23 to see how safe and effective it is within a specific time after their stroke.
Recruiting
EMAGINE 2.0 - Electromagnetic Field Ischemic Stroke - Novel Subacute Treatment
NA Downey, California +4 sites NCT06386874
This trial is looking for adults who have had a recent ischemic stroke. Participants will receive treatment using a wearable device and take part in exercise sessions over several months.
Recruiting
Baby Brain Recovery Study
N/A Madison, Wisconsin NCT05013736
This trial is looking for infants with certain types of brain injuries caused by strokes at birth. Participants will have several visits where they will undergo MRI scans and motor assessments while they sleep.
Recruiting
MitoQ and Ischemic Conditioning To Assess Vascular Health Outcomes
PHASE2 Milwaukee, Wisconsin NCT06930638
This trial is looking for stroke survivors who want to improve their blood vessel function. Participants will try an antioxidant called MitoQ and a method called ischemic conditioning to see if these help with their recovery.
Recruiting
Language Processing and TMS
NA Milwaukee, Wisconsin NCT05425615
This trial is looking for people with a left hemisphere stroke and aphasia, as well as healthy right-handed individuals. Participants will receive TMS treatment to see how it affects language processing.
Recruiting
Safety and Effectiveness of Mechanical Thrombectomy Using the Anaconda ANA Funnel Catheter
NA Jacksonville, Florida +4 sites NCT06370182
This trial is looking for people who have had a recent stroke caused by a blocked large blood vessel. Participants will undergo a procedure using a special catheter to help restore blood flow to the brain.
Recruiting
Transcranial Alternating Current Stimulation (tACS) in Aphasia
NA Milwaukee, Wisconsin NCT04375722
This trial is looking for people who have had a stroke and are experiencing language difficulties, as well as healthy volunteers. Participants will receive a type of brain stimulation to help improve language recovery.
Recruiting
Post-Stroke Aphasia TMS
NA Milwaukee, Wisconsin NCT06974279
This trial is looking for stroke survivors who have difficulty finding words due to aphasia. Participants will receive a treatment that combines a brain stimulation method with language therapy to help improve their speaking abilities.
Recruiting
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery
PHASE3 Birmingham, Alabama +4 sites NCT03907046
This trial is looking for adults who have had a recent brain bleed and have atrial fibrillation. Participants will compare the effects of a medication called apixaban with aspirin to see which better prevents strokes or death.
Recruiting
The AHA Oneida Study
NA Madison, Wisconsin +1 sites NCT07139132
Recruiting
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
PHASE3 Little Rock, Arkansas +4 sites NCT04045665
This trial is looking for patients who develop new atrial fibrillation after heart bypass surgery. Participants will receive a treatment to help prevent blood clots while monitoring their safety and health.
Recruiting
Neuroplasticity Biomarkers in Aphasia
NA Madison, Wisconsin NCT06471127
This trial is looking for people aged 40-90 who have had a stroke and experience issues with language, known as aphasia. Participants will help researchers understand changes in the brain that can affect recovery from aphasia.
Recruiting
The Fourth Left Atrial Appendage Occlusion Study
NA Birmingham, Alabama +4 sites NCT05963698
This trial is looking for people with atrial fibrillation who are at high risk of stroke, even while taking blood thinners. Participants will undergo a procedure to block a specific part of the heart to see if it helps prevent strokes.
Recruiting

Where the Stroke studies are in Wisconsin

  • Medical College of Wisconsin, Milwaukee6 trials
  • Aurora St. Luke's Medical Center, Milwaukee2 trials
  • Froedtert & Medical College of Wisconsin, Milwaukee2 trials
  • Marquette University, Milwaukee2 trials
  • University of Wisconsin, Madison2 trials
  • Ascension Columbia St. Mary's Hospital, Milwaukee1 trial

Counts are recruiting studies listing at least one site in Wisconsin, from ClinicalTrials.gov, refreshed every two days.

Stroke clinical trials in Wisconsin: common questions

How many Stroke clinical trials are recruiting in Wisconsin?
TrialFinder currently lists 19 recruiting Stroke clinical trials with study sites in Wisconsin. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Stroke clinical trials located in Wisconsin?
Study sites for the Stroke trials listed on this page include Madison, Milwaukee. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Stroke clinical trial in Wisconsin?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Stroke trials in Wisconsin also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Stroke clinical trial in Wisconsin?
Each study sets its own criteria based on age, Stroke diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
My stroke was years ago. Are there still trials for me?
Yes. Many recovery trials enroll people six months or more after a stroke, and some accept strokes from many years earlier, because they study whether therapy can still improve movement or speech.
What are stroke rehabilitation trials like?
Intensive and hands-on: therapy sessions several times a week for one to three months, sometimes with a device or stimulation added, and assessments before and after. The comparison group usually gets standard therapy or the program at a later date.
Can a family member join a trial if they cannot consent for themselves?
Some trials allow a legally authorized representative to consent on a participant's behalf, particularly acute and prevention studies; most rehabilitation trials need the participant's own consent and active participation. Ask the study team.
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Stroke trials cover thrombolytic agents, mechanical thrombectomy techniques, neuroprotective drugs, and intensive rehabilitation programmes for acute and chronic stroke.

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