No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
21 and older
Sex
Any
Study type
Interventional
Purpose
Basic Science
Participants needed
30 (estimated)
Sponsor
Marquette University · Other
Who this trial is looking for
This trial is looking for stroke survivors who want to improve their arm control. Participants will use a special device that provides vibrations to help with movement tasks, like reaching and drinking from a glass.
Are You a Good Fit for This Trial?
Rules you outMyasthenia gravisAmyotrophic lateral sclerosisEpilepsySchizophrenia
You may be able to join if
I am a stroke survivor more than 6 months post-stroke.
I can perform specific hand tasks.
I have mild to moderate motor impairment in my arm.
I have a loss of feeling in my elbow on one arm.
I can feel touch in my other arm or thigh.
I can actively extend my wrist at least 5 degrees.
I can give informed consent and follow instructions.
You may not be able to join if
I cannot give informed consent or follow instructions.
I have a bleeding disorder.
I have fixed contractures or had tendon transfer in my arm.
I have myasthenia gravis or similar diseases.
I am using certain neuromuscular interfering medications.
I have a history of epilepsy.
I have serious psychiatric conditions like schizophrenia.
I have tumors in my brain.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Supplementing or augmenting sensory information to those who have lost proprioception after stroke could help improve functional control of the arm. Thirty subjects will be recruited to a single site to evaluate the ability of supplemental kinesthetic feedback (a form of vibrotactile stimulation) to improve motor function. Participants will be tested in performing reaching movements as well as mor…
Supplementing or augmenting sensory information to those who have lost proprioception after stroke could help improve functional control of the arm. Thirty subjects will be recruited to a single site to evaluate the ability of supplemental kinesthetic feedback (a form of vibrotactile stimulation) to improve motor function. Participants will be tested in performing reaching movements as well as more functional tasks such as simulated drinking from a glass
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* stroke survivors who can perform our stabilization and grip modulation tasks and who
* had a single ischemic or hemorrhagic stroke of the middle cerebral artery (MCA) in the chronic state of recovery (\> 6 months post-stroke).
* ability to give informed consent and be able to …
Inclusion Criteria:
* stroke survivors who can perform our stabilization and grip modulation tasks and who
* had a single ischemic or hemorrhagic stroke of the middle cerebral artery (MCA) in the chronic state of recovery (\> 6 months post-stroke).
* ability to give informed consent and be able to follow two-stage instructions.
* mild-to-moderate motor impairment as assessed using the upper extremity (UE) portion of the Fugl-Meyer Motor Assessment (FM); i.e., UE-FM score between 28 and 50 (inclusive) out of a possible 66.
* proprioceptive deficit at the elbow in the more involved (contralesional) arm.
* preserved tactile sensation in either the ipsilesional arm and/or thigh.
* a minimal active wrist extension of 5°.
Exclusion Criteria:
* Inability of subjects to give informed consent or follow two-stage instructions.
* subjects with a bleeding disorder.
* subjects with fixed contractures or a history of tendon transfer in the involved limb.
* subjects with a diagnosis of myasthenia gravis, amyotrophic lateral sclerosis or any disease that might interfere with neuromuscular function.
* subjects who are currently using or under the influence of aminoglycoside antibiotics, curare-like agents, or other agents that may interfere with neuromuscular function.
* subjects with a history of epilepsy.
* history of other psychiatric co-morbidities (e.g. schizophrenia).
* malignant or benign intra-axial neoplasms.
* concurrent illness limiting the capacity to conform to study requirements.
* Cardiac pacemaker, cardiac arrhythmia or history of significant cardiovascular or respiratory compromise.
* subjects with profound atrophy or excessive weakness of muscles in the target area(s) of testing.
* subjects with a systemic infection.
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