No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
288 (estimated)
Sponsor
University of Wisconsin, Madison · Other
Who this trial is looking for
This trial is looking for stroke patients to test two brain stimulation techniques aimed at improving recovery. Participants will either have arm movement difficulties or be healthy individuals.
Are You a Good Fit for This Trial?
You may be able to join if
I have had a stroke
I have arm movement difficulties
I have risk factors for stroke
I do not have any neurological or mental disabilities
You may not be able to join if
I am allergic to electrode gel, surgical tape, or metals
I am pregnant or may become pregnant during the study
I have an infection or oral inflammation
I have contraindications for MRI
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The purpose of this research is to determine if two non-invasive brain stimulation techniques, muscle stimulation of the arm and neuro-stimulation through the tongue, can increase the extent of stroke recovery.
Trial Locations
Loading…
Loading trial locations…
Facility
City
State
Country
Status
Eligibility Criteria
Inclusion Criteria (Experimental Group):
* Stroke patients with persistent upper extremity (UE) deficits
Inclusion Criteria (Control Group 1)
* Stroke patients without UE impairments
* Participants with risk factors for stroke
* healthy controls
* No known neurologic, psychiatric or developmen…
Inclusion Criteria (Experimental Group):
* Stroke patients with persistent upper extremity (UE) deficits
Inclusion Criteria (Control Group 1)
* Stroke patients without UE impairments
* Participants with risk factors for stroke
* healthy controls
* No known neurologic, psychiatric or developmental disability
Inclusion Criteria (Control Group 2)
* Stroke patients with persistent upper extremity (UE) deficits
* Moderate upper extremity (dominant right hand affected) impairment (score of 1 or 2 on the motor sub-component of the NIH stroke scale (NIHSS) and ARAT score 20-45)
* No upper extremity injury or conditions that limited use prior to the stroke
* Pre-stroke independence with a Modified Rankin Score of 0 or 1, for the standard FES only intervention.
Exclusion Criteria (for all participants):
* Allergic to electrode gel, surgical tape and metals
* Participants under treatment for infectious diseases or having apparent oral lesions or inflammation will be excluded from the study
* Women who are pregnant or may become pregnant during the course of the study will be excluded
* Participants with contraindications for MRI will be offered the opportunity to participate in the interventions study only (e.g. EEG-BCI-FES and behavioral testing)
Exclusion Criteria (for healthy controls)
* Contraindications for MRI
* Allergic to electrode gel, surgical tape, and metals.
Picking one helps us show the most relevant trials first.
Your results are loading in the background — you can
change this any time from the results page.
Set your location to continue
Find My Trials uses your location to surface clinical trials near you.
Add your city or zip code to your profile and try again.