19 Recruiting Trials

Clinical Trials
for Stroke in Indiana

19 clinical trials for Stroke are currently recruiting participants at study sites in Indiana. Study-related care is provided at no cost.

19
Recruiting trials
20
Study sites
6
Cities
3
Industry-sponsored
1
Phase 2
5
Phase 3

Stroke clinical trials in Indiana: what to expect

Stroke trials come in three kinds. Acute treatment trials enroll within hours of a stroke, inside the hospital, and are not something you apply to. Recovery and rehabilitation trials enroll from a few weeks to many years after a stroke and test intensive therapy, robotics, brain and nerve stimulation, virtual reality and medicines meant to help the brain rewire. Prevention trials test blood thinners, cholesterol and blood pressure treatments and procedures to lower the chance of a second stroke.

In Indiana, recruiting stroke studies are concentrated in Indianapolis, Munster, Fort Wayne and Bloomington, with sites in 2 other cities. 3 of the 19 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who stroke trials usually look for

Listings state the time since stroke, the type (a clot or a bleed) and the kind of difficulty they study, such as arm and hand weakness, walking, speech or vision, often with a range on a standard scale that the study therapist scores. Many recovery trials enroll people six months or more after their stroke, so an older stroke does not rule you out. Prevention trials look for a stroke or mini-stroke in a recent window plus a specific risk factor such as atrial fibrillation. Most require that you can give consent and take part in sessions.

What taking part involves

Rehabilitation trials are intensive: several sessions a week for four to twelve weeks, with assessments by a therapist before, after and some months later, and sometimes an MRI. The comparison group often receives standard therapy or the same program later. Prevention trials are long and light: a study medicine or placebo added to usual care, visits every few months for several years. Study care and equipment are free and travel is usually reimbursed; a family member is welcome at visits.

Questions worth asking the study team

How many sessions are required and where; whether a comparison group receives the therapy later; whether current rehabilitation can continue; what the assessments involve; and whether transport can be arranged.

Showing 19 of 19 recruiting Stroke trials in Indiana

Overground Virtual Reality (VR) Gait Rehabilitation for Stroke
NA Indianapolis, Indiana NCT07676578
This trial is looking for stroke survivors who want to improve their walking abilities. Participants will compare a new virtual reality therapy for walking with a traditional treadmill-based therapy.
Recruiting
Variable Intensive Early Walking Post-Stroke - 2 (VIEWS-2)
NA Indianapolis, Indiana NCT05727930
This trial is looking for people who have had a stroke within the last 1 to 6 months. Participants will take part in a walking therapy program to help improve their ability to move and enjoy life more.
Recruiting
Locomotor Recovery and Compensation Post-stroke (LRC)
NA Indianapolis, Indiana NCT05081713
This trial is looking for individuals who are recovering from their first stroke and are currently in rehabilitation. Participants will help researchers understand how recovery and compensation for movement can change over time.
Recruiting
High vs Low-frequency of High-intensity Training in Chronic Stroke
NA Indianapolis, Indiana NCT06612723
This trial is looking for people who have had a stroke more than 6 months ago to see how the frequency of training affects walking recovery. Participants will receive high-intensity gait training and a home walking program.
Recruiting
Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials
N/A Birmingham, Alabama +4 sites NCT05338697
This trial is looking for adults who have had a stroke and are experiencing motor difficulties in one arm. Participants will undergo specific tests and procedures to help researchers understand recovery outcomes.
Recruiting
Stroke Thrombectomy and Aneurysm Registry
N/A Birmingham, Alabama +4 sites NCT04994756
This trial is looking for patients undergoing surgery for brain injuries. Participants will help collect information about their treatment and outcomes.
Recruiting
Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial
PHASE3 Mobile, Alabama +4 sites NCT05611242
This trial is looking for adults aged 18 to 79 who have had an acute ischemic stroke. Participants will receive a specific treatment for blocked arteries in the brain to see if it's more effective than other approaches.
Recruiting
The Pivotal Study of RapidPulseTM Aspiration System
NA Torrance, California +4 sites NCT06029491
This trial is looking for adults aged 18 to 80 who have had a stroke within the last 8 hours. Participants will receive a treatment to remove a blood clot in the brain and will be monitored for 90 days.
Recruiting
Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY
N/A Phoenix, Arizona +4 sites NCT04916210
This trial is looking for adults who have had a stroke and want to help researchers learn more about how strokes affect thinking and memory. Participants will undergo evaluations to understand their recovery and brain health after a stroke.
Recruiting
Rapid Evacuation and Access of Cerebral Hemorrhage Trial
NA Birmingham, Alabama +4 sites NCT06870812
This trial is looking for adults with a specific type of brain bleed to compare surgery with standard medical care. Participants will receive either surgery to remove blood from the brain or regular medical treatment.
Recruiting
Wearable Biofeedback for Swallowing Disorders Rehabilitation in Stroke and Parkinson Disease
PHASE2 West Lafayette, Indiana +1 sites NCT06638944
This trial is looking for people aged 50-90 with swallowing difficulties related to stroke or Parkinson's disease. Participants will use a new wearable device to help improve their swallowing while receiving standard therapy.
Recruiting
Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable
PHASE3 Dothan, Alabama +4 sites NCT07430956
This trial is looking for adults with atrial fibrillation who are unable or choose not to take blood thinners. Participants will take one of two study drugs to see how well they help prevent strokes and blood clots.
Recruiting
Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation
PHASE3 Alexander City, Alabama +4 sites NCT07626411
This trial is looking for adults with atrial fibrillation who need treatment to prevent strokes. Participants will receive either the study drug REGN7508 or another medication called apixaban.
Recruiting
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery
PHASE3 Birmingham, Alabama +4 sites NCT03907046
This trial is looking for adults who have had a recent brain bleed and have atrial fibrillation. Participants will compare the effects of a medication called apixaban with aspirin to see which better prevents strokes or death.
Recruiting
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
PHASE3 Little Rock, Arkansas +4 sites NCT04045665
This trial is looking for patients who develop new atrial fibrillation after heart bypass surgery. Participants will receive a treatment to help prevent blood clots while monitoring their safety and health.
Recruiting
Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage
N/A Irvine, California +4 sites NCT06402968
This trial is looking for adults who have high blood pressure after a stroke. Participants will receive either clevidipine or another treatment to help manage their blood pressure within 60 minutes.
Recruiting
CTSN Embolic Protection Trial
NA Bloomington, Indiana +4 sites NCT06027788
This trial is looking for patients aged 60 and older who are scheduled for certain types of heart valve surgeries. By participating, I would be helping to test a device designed to protect the heart during the procedure.
Recruiting
The Fourth Left Atrial Appendage Occlusion Study
NA Birmingham, Alabama +4 sites NCT05963698
This trial is looking for people with atrial fibrillation who are at high risk of stroke, even while taking blood thinners. Participants will undergo a procedure to block a specific part of the heart to see if it helps prevent strokes.
Recruiting

Where the Stroke studies are in Indiana

  • Indiana University, Indianapolis3 trials
  • Rehabilitation Hospital of Indiana, Indianapolis3 trials
  • IU Health Methodist Hospital, Indianapolis2 trials
  • Profound Research, Powers Health Medical Group - Electrophysiology, Munster2 trials
  • Ascension St. Vincent, Indianapolis1 trial
  • Cardiovascular Research of Northwest Indiana, LLC, Munster1 trial

Counts are recruiting studies listing at least one site in Indiana, from ClinicalTrials.gov, refreshed every two days.

Stroke clinical trials in Indiana: common questions

How many Stroke clinical trials are recruiting in Indiana?
TrialFinder currently lists 19 recruiting Stroke clinical trials with study sites in Indiana. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Stroke clinical trials located in Indiana?
Study sites for the Stroke trials listed on this page include Indianapolis, West Lafayette, Bloomington. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Stroke clinical trial in Indiana?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Stroke trials in Indiana also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Stroke clinical trial in Indiana?
Each study sets its own criteria based on age, Stroke diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
My stroke was years ago. Are there still trials for me?
Yes. Many recovery trials enroll people six months or more after a stroke, and some accept strokes from many years earlier, because they study whether therapy can still improve movement or speech.
What are stroke rehabilitation trials like?
Intensive and hands-on: therapy sessions several times a week for one to three months, sometimes with a device or stimulation added, and assessments before and after. The comparison group usually gets standard therapy or the program at a later date.
Can a family member join a trial if they cannot consent for themselves?
Some trials allow a legally authorized representative to consent on a participant's behalf, particularly acute and prevention studies; most rehabilitation trials need the participant's own consent and active participation. Ask the study team.
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Stroke trials cover thrombolytic agents, mechanical thrombectomy techniques, neuroprotective drugs, and intensive rehabilitation programmes for acute and chronic stroke.

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