No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
30 (estimated)
Sponsor
Indiana University · Other
Who this trial is looking for
This trial is looking for stroke survivors who want to improve their walking abilities. Participants will compare a new virtual reality therapy for walking with a traditional treadmill-based therapy.
Are You a Good Fit for This Trial?
Rules you outParkinson's diseaseMultiple sclerosis
You may be able to join if
I have had a stroke in the last 1-6 months.
I can walk with some assistance and have a moderate level of motor impairment.
I have passed a cognitive test with a score of 24 or higher.
I have my doctor's approval to participate in this program.
I need help with my walking as shown in a timed walking test.
I can give informed consent for myself.
You may not be able to join if
I have uncontrolled heart or metabolic issues.
I have other medical conditions affecting my ability to walk.
I have participated in any gait training using robots or VR in the last 6 months.
I cannot handle virtual reality environments.
I have severe problems with my thinking, seeing, or hearing.
I have pre-existing neurological conditions unrelated to my stroke.
I scored 12 or higher on the Disability Rating Scale.
I have received physical therapy in the last month.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The purpose of this study is to evaluate a new virtual reality (VR)-based rehabilitation program designed to help stroke survivors improve their walking abilities in real-world settings. By comparing immersive VR-assisted overground gait therapy to contemporary non-immersive, treadmill-based VR therapy (i.e., C-Mill), the investigators aim to determine its effectiveness in enhancing mobility and q…
The purpose of this study is to evaluate a new virtual reality (VR)-based rehabilitation program designed to help stroke survivors improve their walking abilities in real-world settings. By comparing immersive VR-assisted overground gait therapy to contemporary non-immersive, treadmill-based VR therapy (i.e., C-Mill), the investigators aim to determine its effectiveness in enhancing mobility and quality of life for stroke survivors.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Diagnosis: Anischemic or hemorrhagic stroke verified by imaging, confirmed by the patient's physician, and 1-6 months post-stroke (subacute phase)
* Motor Impairment Level: Functional Ambulation Category (FAC) 3-5, showing moderate impairment while still allowing safe particip…
Inclusion Criteria:
* Diagnosis: Anischemic or hemorrhagic stroke verified by imaging, confirmed by the patient's physician, and 1-6 months post-stroke (subacute phase)
* Motor Impairment Level: Functional Ambulation Category (FAC) 3-5, showing moderate impairment while still allowing safe participation in gait tasks.
* Cognitive Function: Mini-Mental State Examination (MMSE) score ≥ 24 or Montreal Cognitive Assessment (MoCA) score \>= 20, indicating sufficient cognitive function to participate in the study.
* Exercise Clearance: Approval from a physician for participation in exercise- and VR-based interventions.
* Rehabilitation Need: 10-Meter Walk Test \<1.0 m/s, as timed by a PT during screening, indicating a need for functional rehabilitation.
* Consent: Must be able to provide informed consent for themselves.
Exclusion Criteria:
* Participants with uncontrolled cardiovascular, orthopedic, or metabolic conditions or unstable medication regimens that could interfere with their participation in the study.
* Any comorbidity that could interfere with walking or gait training.
* Participation in robot- or VR-assisted gait training within the last 6 months.
* Intolerance to virtual reality environments or motion simulation.
* Severe cognitive, visual, or hearing impairments where the participant cannot follow the therapist's instructions.
* Any other condition deemed unsafe or confounding by investigator, such as pre-existing neurological conditions unrelated to stroke (e.g. Parkinson's, multiple sclerosis), unmanaged pain medications, or acute medical events during the screening period (e.g. recurrent stroke, hospitalization).
* Individuals who score a 12 or higher on the Disability Rating Scale.
* Recent Therapy: Participants should not have received physical therapy (PT) within the last month.
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