7 Recruiting Trials

Clinical Trials
for Parkinson's in Indiana

7 clinical trials for Parkinson's are currently recruiting participants at study sites in Indiana. Study-related care is provided at no cost.

7
Recruiting trials
5
Study sites
2
Cities
4
Industry-sponsored
4
Phase 2
1
Phase 3

Parkinson's clinical trials in Indiana: what to expect

Parkinson's trials fall into three groups. Disease-modifying studies test drugs meant to slow progression, including treatments aimed at alpha-synuclein, repurposed diabetes drugs and therapies for people with LRRK2 or GBA gene variants. Symptom studies test new ways to smooth out "off" periods and dyskinesia, and procedures such as focused ultrasound and deep brain stimulation. And a large number of studies involve no medicine: exercise, speech and balance programs, wearables, and long-term observational studies that track the disease.

In Indiana, recruiting parkinson's studies are concentrated in Indianapolis and West Lafayette. 4 of the 7 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who Parkinson's trials usually look for

Disease-modifying trials usually enroll people diagnosed in the last two to five years, sometimes before any Parkinson's medicine has started. Symptom trials want people on levodopa who have a stated number of hours of "off" time a day. Most set ages 30 to 80, exclude dementia and atypical parkinsonism, and may require a dopamine transporter scan to confirm the diagnosis. Genetic trials test for the variant at no cost. Exercise and observational studies accept a much wider range.

What taking part involves

Screening includes a movement exam, sometimes performed both before and after your morning dose, blood work and a scan. Drug trials run twelve weeks to two years with monthly visits, symptom diaries and, in some, a spinal fluid test. Placebo arms are common and medicines you already take generally continue. Exercise and rehabilitation trials involve sessions two or three times a week for several months. Everything study-related is free and travel is usually reimbursed; a care partner is welcome and sometimes required.

Questions worth asking the study team

Whether you must skip a dose before visits; whether your current medicines continue; what the chance of placebo is and whether an extension follows; how many visits are required; and whether you will be told the results of any scans or genetic tests.

Showing 7 of 7 recruiting Parkinson's trials in Indiana

Parkinson's Foundation PD GENEration Genetic Registry
N/A Birmingham, Alabama +4 sites NCT04994015
This trial is looking for people with Parkinson's disease who are willing to undergo genetic testing. Participants will help build a genetic database for future research on the condition.
Recruiting
A Study of Buntanetap in Participants With PD
PHASE2 Birmingham, Alabama +4 sites NCT07284784
This trial is looking for adults with Parkinson's Disease who are either already on deep brain stimulation treatment or have participated in earlier trials with buntanetap. Participants will take the medication for 36 months and attend regular check-ups.
Recruiting
Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry
N/A Aliso Viejo, California +4 sites NCT02071134
This trial is looking for adults with Parkinson’s disease to evaluate a device called the Vercise DBS System. Participants will help gather information on the device's effectiveness in treating their condition.
Recruiting
Rehabilitation of Airway Protection in Parkinson's Disease
PHASE2 West Lafayette, Indiana +1 sites NCT05700825
This trial is looking for people with Parkinson's Disease who have trouble swallowing. Participants will receive either in-person or remote therapy to help improve their ability to protect their airways while swallowing.
Recruiting
A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations
PHASE2 Little Rock, Arkansas +4 sites NCT07432958
This trial is looking for people with Parkinson's disease who have motor fluctuations while taking their medication. Participants will receive either the study drug AP-472 or a placebo for about 12 weeks to see how well it works.
Recruiting
Wearable Biofeedback for Swallowing Disorders Rehabilitation in Stroke and Parkinson Disease
PHASE2 West Lafayette, Indiana +1 sites NCT06638944
This trial is looking for people aged 50-90 with swallowing difficulties related to stroke or Parkinson's disease. Participants will use a new wearable device to help improve their swallowing while receiving standard therapy.
Recruiting
Abbott DBS Post-Market Study of Outcomes for Indications Over Time
N/A Tucson, Arizona +4 sites NCT04071847
This trial is looking for people who need deep brain stimulation surgery for conditions like Parkinson's disease or tremors. Participants will help evaluate the long-term safety and effectiveness of the Abbott DBS system.
Recruiting

Where the Parkinson's studies are in Indiana

  • Indiana University, Indianapolis2 trials
  • Purdue University, West Lafayette2 trials
  • Josephson Wallack Munshower Neurology PC (Site #231), Indianapolis1 trial
  • Josephson Wallack Munshower Neurology, P.C., Indianapolis1 trial
  • Methodist Hospital of Indianapolis, Indianapolis1 trial

Counts are recruiting studies listing at least one site in Indiana, from ClinicalTrials.gov, refreshed every two days.

Parkinson's clinical trials in Indiana: common questions

How many Parkinson's clinical trials are recruiting in Indiana?
TrialFinder currently lists 7 recruiting Parkinson's clinical trials with study sites in Indiana. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Parkinson's clinical trials located in Indiana?
Study sites for the Parkinson's trials listed on this page include West Lafayette. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Parkinson's clinical trial in Indiana?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Parkinson's trials in Indiana also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Parkinson's clinical trial in Indiana?
Each study sets its own criteria based on age, Parkinson's diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Can I join a Parkinson's trial if I take carbidopa-levodopa?
Yes for most trials, including every study of "off" time. Some disease-modifying trials want people who have not started medicine yet; the listing says so.
What does "off time" mean in a trial listing?
The hours each day when your medicine has worn off and symptoms return. Trials of new symptom treatments usually require about two or more hours of off time a day, recorded in a diary during screening.
Are there Parkinson's trials that do not involve medicine?
Many. Exercise, speech, balance and dance programs, wearable sensors, deep brain stimulation settings and observational studies all recruit, and most accept people at any stage who can attend sessions.
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Parkinson's disease trials test dopamine-replacement therapies, deep brain stimulation, gene therapies, and neuroprotective compounds to slow disease progression.

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