4 Recruiting Trials

Clinical Trials
for Parkinson's in Iowa

4 clinical trials for Parkinson's are currently recruiting participants at study sites in Iowa. Study-related care is provided at no cost.

4
Recruiting trials
3
Study sites
2
Cities
1
Phase 2

Parkinson's clinical trials in Iowa: what to expect

Parkinson's trials fall into three groups. Disease-modifying studies test drugs meant to slow progression, including treatments aimed at alpha-synuclein, repurposed diabetes drugs and therapies for people with LRRK2 or GBA gene variants. Symptom studies test new ways to smooth out "off" periods and dyskinesia, and procedures such as focused ultrasound and deep brain stimulation. And a large number of studies involve no medicine: exercise, speech and balance programs, wearables, and long-term observational studies that track the disease.

In Iowa, recruiting parkinson's studies are concentrated in Iowa City and Waterloo.

Who Parkinson's trials usually look for

Disease-modifying trials usually enroll people diagnosed in the last two to five years, sometimes before any Parkinson's medicine has started. Symptom trials want people on levodopa who have a stated number of hours of "off" time a day. Most set ages 30 to 80, exclude dementia and atypical parkinsonism, and may require a dopamine transporter scan to confirm the diagnosis. Genetic trials test for the variant at no cost. Exercise and observational studies accept a much wider range.

What taking part involves

Screening includes a movement exam, sometimes performed both before and after your morning dose, blood work and a scan. Drug trials run twelve weeks to two years with monthly visits, symptom diaries and, in some, a spinal fluid test. Placebo arms are common and medicines you already take generally continue. Exercise and rehabilitation trials involve sessions two or three times a week for several months. Everything study-related is free and travel is usually reimbursed; a care partner is welcome and sometimes required.

Questions worth asking the study team

Whether you must skip a dose before visits; whether your current medicines continue; what the chance of placebo is and whether an extension follows; how many visits are required; and whether you will be told the results of any scans or genetic tests.

Showing 4 of 4 recruiting Parkinson's trials in Iowa

Parkinson's Foundation PD GENEration Genetic Registry
N/A Birmingham, Alabama +4 sites NCT04994015
This trial is looking for people with Parkinson's disease who are willing to undergo genetic testing. Participants will help build a genetic database for future research on the condition.
Recruiting
Home-Based Monitoring in Parkinson's Disease
N/A Iowa City, Iowa NCT06573762
This trial is looking for people with possible or recent Parkinson's disease. Participants will perform tasks at home, track their activity with a device, and make recordings to help understand the disease better.
Recruiting
Tenapanor in Synucleinopathy-Related Constipation
PHASE2 Waterloo, Iowa NCT06460038
This trial is looking for individuals who have Parkinson's disease and experience constipation. Participants will need to meet certain health criteria and will be monitored for their bowel habits during the study.
Recruiting
Cerebellar Stimulation and Cognitive Control
NA Iowa City, Iowa NCT03217110
This trial is looking for patients with depression, autism, bipolar disorder, Parkinson's disease, or schizophrenia. Participants will receive cerebellar stimulation to see if it can help improve their mood and thinking abilities.
Recruiting

Where the Parkinson's studies are in Iowa

  • University of Iowa, Iowa City2 trials
  • Cedar Valley Digestive Health Center, Waterloo1 trial
  • University of Iowa Hospitals and Clinics, Iowa City1 trial

Counts are recruiting studies listing at least one site in Iowa, from ClinicalTrials.gov, refreshed every two days.

Parkinson's clinical trials in Iowa: common questions

How many Parkinson's clinical trials are recruiting in Iowa?
TrialFinder currently lists 4 recruiting Parkinson's clinical trials with study sites in Iowa. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Parkinson's clinical trials located in Iowa?
Study sites for the Parkinson's trials listed on this page include Iowa City, Waterloo. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Parkinson's clinical trial in Iowa?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Parkinson's trials in Iowa also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Parkinson's clinical trial in Iowa?
Each study sets its own criteria based on age, Parkinson's diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Can I join a Parkinson's trial if I take carbidopa-levodopa?
Yes for most trials, including every study of "off" time. Some disease-modifying trials want people who have not started medicine yet; the listing says so.
What does "off time" mean in a trial listing?
The hours each day when your medicine has worn off and symptoms return. Trials of new symptom treatments usually require about two or more hours of off time a day, recorded in a diary during screening.
Are there Parkinson's trials that do not involve medicine?
Many. Exercise, speech, balance and dance programs, wearable sensors, deep brain stimulation settings and observational studies all recruit, and most accept people at any stage who can attend sessions.
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Parkinson's disease trials test dopamine-replacement therapies, deep brain stimulation, gene therapies, and neuroprotective compounds to slow disease progression.

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