37 Recruiting Trials

Clinical Trials
for Parkinson's in New York

37 clinical trials for Parkinson's are currently recruiting participants at study sites in New York. Study-related care is provided at no cost.

37
Recruiting trials
45
Study sites
13
Cities
20
Industry-sponsored
10
Phase 2
4
Phase 3

Parkinson's clinical trials in New York: what to expect

Parkinson's trials fall into three groups. Disease-modifying studies test drugs meant to slow progression, including treatments aimed at alpha-synuclein, repurposed diabetes drugs and therapies for people with LRRK2 or GBA gene variants. Symptom studies test new ways to smooth out "off" periods and dyskinesia, and procedures such as focused ultrasound and deep brain stimulation. And a large number of studies involve no medicine: exercise, speech and balance programs, wearables, and long-term observational studies that track the disease.

In New York, recruiting parkinson's studies are concentrated in New York, Albany, Rochester and Commack, with sites in 9 other cities. 20 of the 37 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who Parkinson's trials usually look for

Disease-modifying trials usually enroll people diagnosed in the last two to five years, sometimes before any Parkinson's medicine has started. Symptom trials want people on levodopa who have a stated number of hours of "off" time a day. Most set ages 30 to 80, exclude dementia and atypical parkinsonism, and may require a dopamine transporter scan to confirm the diagnosis. Genetic trials test for the variant at no cost. Exercise and observational studies accept a much wider range.

What taking part involves

Screening includes a movement exam, sometimes performed both before and after your morning dose, blood work and a scan. Drug trials run twelve weeks to two years with monthly visits, symptom diaries and, in some, a spinal fluid test. Placebo arms are common and medicines you already take generally continue. Exercise and rehabilitation trials involve sessions two or three times a week for several months. Everything study-related is free and travel is usually reimbursed; a care partner is welcome and sometimes required.

Questions worth asking the study team

Whether you must skip a dose before visits; whether your current medicines continue; what the chance of placebo is and whether an extension follows; how many visits are required; and whether you will be told the results of any scans or genetic tests.

Showing 20 of 37 recruiting Parkinson's trials in New York

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease
PHASE3 Birmingham, Alabama +4 sites NCT07174310
This trial is looking for people with early-stage Parkinson's disease who are currently on stable treatment with levodopa. Participants will receive either the drug prasinezumab or a placebo to study its effects.
Recruiting
A Multicenter Study to Evaluate Safety, Tolerability, and Clinical Responses of DSP-1083 Into Subjects With Parkinson's Disease
PHASE1 New York, New York +2 sites NCT06753331
This trial is looking for adults with Parkinson's disease who have been living with the condition for at least 4 years and are not fully controlling their symptoms with current medications. Participants will receive a treatment called DSP-1083 to evaluate its safety and how well it works.
Recruiting
Speech Learning and Speech Production in Parkinson's Disease
NA Buffalo, New York NCT07403539
This trial is looking for people with Parkinson's disease who have difficulties with talking and understanding speech. Participants will help researchers explore ways to improve these abilities.
Recruiting
Parkinson's Foundation PD GENEration Genetic Registry
N/A Birmingham, Alabama +4 sites NCT04994015
This trial is looking for people with Parkinson's disease who are willing to undergo genetic testing. Participants will help build a genetic database for future research on the condition.
Recruiting
A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications
N/A Phoenix, Arizona +4 sites NCT07330258
This trial is looking for people with Parkinson's disease who still have movement symptoms even though they are on medication. Participants will help researchers understand how the condition changes over time without altering their current treatment.
Recruiting
A Study of Buntanetap in Participants With PD
PHASE2 Birmingham, Alabama +4 sites NCT07284784
This trial is looking for adults with Parkinson's Disease who are either already on deep brain stimulation treatment or have participated in earlier trials with buntanetap. Participants will take the medication for 36 months and attend regular check-ups.
Recruiting
A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease
PHASE3 Scottsdale, Arizona +4 sites NCT06944522
This trial is looking for adults with Parkinson's Disease who are between 45 and 75 years old. Participants will receive a treatment called bemdaneprocel to see how well it works and if it is safe.
Recruiting
Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis
PHASE4 Tucson, Arizona +4 sites NCT04373317
This trial is looking for veterans aged 40 or older who have Parkinson's disease and experience symptoms like hallucinations or delusions. Participants will take either Pimavanserin or Quetiapine, and will need to attend study visits regularly.
Recruiting
Effects of Osteopathic Manipulative Treatment Protocol on Sleep Quality in Parkinson's Disease Subjects
NA Old Westbury, New York NCT06671600
This trial is looking for people with Parkinson's disease who have trouble sleeping. Participants will either receive osteopathic treatment or a light touch treatment to see which helps improve sleep quality.
Recruiting
A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Thalamotomy for the Treatment of Medication-Refractory Tremor Dominant Idiopathic Parkinson's Disease
N/A New York, New York +4 sites NCT04991831
This trial is looking for adults with tremors from Parkinson's disease. Participants will undergo a specific procedure to see how safe and effective it is over time.
Recruiting
Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry
N/A Aliso Viejo, California +4 sites NCT02071134
This trial is looking for adults with Parkinson’s disease to evaluate a device called the Vercise DBS System. Participants will help gather information on the device's effectiveness in treating their condition.
Recruiting
A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease
PHASE2 Sun City, Arizona +4 sites NCT06680830
This trial is looking for men and women aged 40-80 who have early Parkinson's Disease and a specific genetic profile. Participants will take part in a study to evaluate the safety and effectiveness of a new treatment called NEU-411.
Recruiting
Effects of Transcranial Focused Ultrasound Stimulation (tFUS) on Neurological and Cognitive Outcomes in Parkinson's Disease
NA New York, New York +3 sites NCT07207122
This trial is looking for adults with Parkinson's disease to test a new treatment called transcranial focused ultrasound. Participants will receive the treatment and be monitored for safety and effectiveness.
Recruiting
GBPDC: Gut-Brain in PD Consortium Master Protocol
N/A Stanford, California +4 sites NCT07567794
This trial is looking for people with Parkinson's disease and those without it to study the gut-brain connection. Participants will undergo various health assessments, including questionnaires, tests, and samples of blood and stool, over a period of up to 24 months.
Recruiting
A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Pallidotomy for the Treatment of Advanced, Idiopathic Parkinson's Disease With Medication-refractory Moderate to Severe Motor Complications
N/A New York, New York +4 sites NCT05539196
This trial is looking for people aged 30 and older with advanced Parkinson's disease who have motor complications and are planning to receive the Exablate procedure. Participants will need to visit the registry for follow-ups at 3, 6, and 12 months, and then every year for 5 years.
Recruiting
A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease
PHASE2 Birmingham, Alabama +4 sites NCT06976268
This trial is looking for adults aged 40 to 80 with early Parkinson's disease. Participants will receive treatment over 48 weeks, followed by another 48 weeks of open access to the treatment.
Recruiting
Rehabilitation of Airway Protection in Parkinson's Disease
PHASE2 New York, New York +1 sites NCT05700825
This trial is looking for people with Parkinson's Disease who have trouble swallowing. Participants will receive either in-person or remote therapy to help improve their ability to protect their airways while swallowing.
Recruiting
A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations
PHASE2 Little Rock, Arkansas +4 sites NCT07432958
This trial is looking for people with Parkinson's disease who have motor fluctuations while taking their medication. Participants will receive either the study drug AP-472 or a placebo for about 12 weeks to see how well it works.
Recruiting
Low-dose Carbon Monoxide (HBI-002) Trial to Evaluate Safety, Tolerability, PK, and Biomarkers in Parkinson's Disease
PHASE2 Fountain Valley, California +4 sites NCT07005180
This trial is looking for people between the ages of 40 and 80 who have been diagnosed with Parkinson's disease and have been using a specific Parkinson's medication for at least a month. It’s important that they haven’t smoked in the last five years and that they are generally in good health. Also, they need to have someone at home who can help keep an eye on them after taking the medication.
Recruiting
A Study of AAV2-GDNF in Adults With Moderate Parkinson's Disease (REGENERATE-PD)
PHASE2 Phoenix, Arizona +4 sites NCT06285643
This trial is looking for adults aged 45-75 with moderate Parkinson's disease. Participants will receive a treatment involving a surgical procedure and will be monitored for safety and effectiveness.
Recruiting

Where the Parkinson's studies are in New York

  • Columbia University, New York4 trials
  • NYU Langone Health, New York3 trials
  • Weill Cornell Medicine, New York3 trials
  • Albany Medical Center, Albany2 trials
  • Columbia University Medical Center, New York2 trials
  • Parkinson's Research Centers of America - Long Island, Commack2 trials

Counts are recruiting studies listing at least one site in New York, from ClinicalTrials.gov, refreshed every two days.

Parkinson's clinical trials in New York: common questions

How many Parkinson's clinical trials are recruiting in New York?
TrialFinder currently lists 37 recruiting Parkinson's clinical trials with study sites in New York. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Parkinson's clinical trials located in New York?
Study sites for the Parkinson's trials listed on this page include New York, Buffalo, Old Westbury. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Parkinson's clinical trial in New York?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Parkinson's trials in New York also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Parkinson's clinical trial in New York?
Each study sets its own criteria based on age, Parkinson's diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Can I join a Parkinson's trial if I take carbidopa-levodopa?
Yes for most trials, including every study of "off" time. Some disease-modifying trials want people who have not started medicine yet; the listing says so.
What does "off time" mean in a trial listing?
The hours each day when your medicine has worn off and symptoms return. Trials of new symptom treatments usually require about two or more hours of off time a day, recorded in a diary during screening.
Are there Parkinson's trials that do not involve medicine?
Many. Exercise, speech, balance and dance programs, wearable sensors, deep brain stimulation settings and observational studies all recruit, and most accept people at any stage who can attend sessions.
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Parkinson's disease trials test dopamine-replacement therapies, deep brain stimulation, gene therapies, and neuroprotective compounds to slow disease progression.

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