46 Recruiting Trials
Clinical Trials
for Alzheimer's in New York
46 clinical trials for Alzheimer's are currently recruiting participants at study sites in New York. Study-related care is provided at no cost.
46
Recruiting trials
71
Study sites
23
Cities
28
Industry-sponsored
13
Phase 2
18
Phase 3
Alzheimer's clinical trials in New York: what to expect
Alzheimer's trials now span the whole course of the disease. Prevention studies enroll people with normal memory who have early signs of amyloid in the brain; treatment studies enroll people with mild cognitive impairment or early Alzheimer's and test the next generation of antibodies, tau-targeting drugs and combinations; and symptom studies address agitation, sleep and depression in later stages. Alongside drugs there are trials of exercise, cognitive training, blood tests for diagnosis and support programs for care partners.
In New York, recruiting alzheimer's studies are concentrated in New York, Syracuse, Albany and Staten Island, with sites in 19 other cities. 28 of the 46 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.
Who Alzheimer's trials usually look for
Most drug trials enroll ages 50 to 85 and define a stage with a memory test score range, then confirm Alzheimer's with an amyloid PET scan, a spinal fluid test or, increasingly, a blood test, all done by the study. Nearly every trial requires a study partner: someone who knows you well, attends visits and answers questions about daily life. Common exclusions are another cause of memory loss, a recent stroke and, for antibody trials, some blood thinners or MRI findings. Prevention trials enroll people with no symptoms at all.
What taking part involves
Screening is longer than for most conditions, often several visits over a few weeks with memory testing, an MRI and an amyloid test. Antibody trials then involve an infusion or injection every two to four weeks, regular safety MRIs and visits for eighteen months to four years, with an extension in which everyone receives the drug. Lifestyle trials involve classes or coaching for six to twenty-four months. All study care is free and travel is usually reimbursed for you and your partner.
Questions worth asking the study team
Whether you will be told your amyloid or genetic results; what the MRI safety monitoring involves; how much time the study partner must give; whether there is an extension after the placebo period; and what happens if memory worsens during the study.
Showing 20 of 46 recruiting Alzheimer's trials in New York
A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease
Recruiting
This trial is looking for people who show signs of Alzheimer's disease but are currently not experiencing cognitive impairment. Participants will receive treatment and help researchers understand its effects on preventing further progression of Alzheimer's.
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
Recruiting
This trial is looking for people with Alzheimer's disease who are experiencing cognitive impairment. Participants will take the medications KarXT and KarX-EC and attend scheduled visits with a caregiver throughout the study.
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease
Recruiting
This trial is looking for adults with agitation related to Alzheimer's Disease. Participants will receive a treatment and will be asked to have their caregiver attend visits and help with the study.
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
Recruiting
This trial is looking for people with mild to moderate Alzheimer's disease who want to help test a new treatment. Participants will need a caregiver to support them and attend study visits.
Safety Assessment of Leronlimab and Its Effect on Brain Inflammation in Alzheimer's Disease
Recruiting
This trial is looking for adults over 50 with Alzheimer's disease or mild cognitive impairment. Participants will take the drug leronlimab once a week for 12 weeks and undergo some tests like brain scans and blood work.
Open-label Extension Study in Participants With Early Alzheimer's Disease
Recruiting
This trial is looking for people with early Alzheimer's disease who have completed a previous study. Participants will receive the study medicine GSK4527226 and help researchers learn about its long-term safety and effectiveness.
ACP-204 in Adults With Alzheimer's Disease Psychosis
Recruiting
This trial is looking for adults aged 55 to 95 who have Alzheimer's disease psychosis. Participants will receive either ACP-204 or a placebo for six weeks, with follow-up visits to check on their health afterwards.
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
Recruiting
This trial is looking for individuals who may qualify for Alzheimer's disease research studies. Participants will be assessed to see if they can join related interventional studies.
Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)
Recruiting
This trial is looking for people who have completed previous studies on KarXT for Alzheimer's-related psychosis. Participants will take KarXT for a year to help researchers understand its long-term safety and tolerability.
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)
Recruiting
This trial is looking for men and women aged 55 to 90 who have Alzheimer's disease along with symptoms like hallucinations or delusions. They need to have a stable living situation and a trusted person who sees them regularly. However, people with certain other mental health conditions or serious medical issues will not be eligible to participate.
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)
Recruiting
This trial is looking for older adults with psychosis associated with Alzheimer's Disease. Participants will be randomly assigned to receive either KarXT or a placebo for 38 weeks, with regular visits to monitor their condition.
Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer's Disease Dementia
Recruiting
This trial is looking for adults aged 55 to 90 with Alzheimer's disease dementia who experience significant agitation. Participants will be evaluated to see how safe and effective the treatments EXV-802 and EXV-801 are for reducing their agitation.
A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
Recruiting
This trial is looking for people with early Alzheimer's disease symptoms. Participants will take part in tests to evaluate their memory and cognitive abilities while receiving treatment.
A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
Recruiting
This trial is looking for people with early symptoms of Alzheimer's disease. Participants will take a medication called trontinemab and go through tests like imaging and assessments to see how well the treatment works and if it is safe.
A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
Recruiting
This trial is looking for adults aged 18 and older who have a specific genetic mutation linked to early Alzheimer's disease or have a family history of it, but are not showing any signs of cognitive decline yet. They also ask that women who could become pregnant use effective birth control during the study. If someone has significant health issues or cannot communicate in the approved language, they won’t be able to participate.
A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
Recruiting
This trial is looking for adults at risk for Alzheimer's disease caused by genetic mutations. If eligible, I will take a study drug and undergo various tests to help assess its effects on the disease.
A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)
Recruiting
This trial is looking for people with early Alzheimer's disease who want to help researchers learn if a new treatment called MK-2214 can help slow down brain changes. Participants will take MK-2214 or a placebo and be monitored for safety and effects.
A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis
Recruiting
This trial is looking for men and women aged 55 to 90 who have Alzheimer's disease and are experiencing symptoms like hallucinations or delusions. They need to have been living in the same place for at least six weeks and have a support person who can help track their health. However, it’s important to note that people who are seriously ill, have other major medical issues, or have substance abuse problems can't participate.
Dominantly Inherited Alzheimer Network (DIAN)
Recruiting
This trial is looking for adults who are children of someone with Alzheimer's disease and have not shown symptoms themselves. Participants will help researchers find signs that might predict who will develop Alzheimer's disease in the future.
A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)
Recruiting
This trial is looking for people with agitation related to Alzheimer's Disease who have completed earlier studies. Participants will take a combination of two specific medications to see how well they work over time and if they are safe.
Where the Alzheimer's studies are in New York
Research sites running the most studies
- Alzheimer's Disease Research Center, Albany3 trials
- Basil Clinical, Laurelton3 trials
- NYU Langone Health, New York3 trials
- SUNY Upstate Medical University, Syracuse3 trials
- AD-CARE, University of Rochester Medical Center, Rochester2 trials
- Adams Clinical Bronx, The Bronx2 trials
By city
Counts are recruiting studies listing at least one site in New York, from ClinicalTrials.gov, refreshed every two days.
Alzheimer's clinical trials in New York: common questions
How many Alzheimer's clinical trials are recruiting in New York?
TrialFinder currently lists 46 recruiting Alzheimer's clinical trials with study sites in New York. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Alzheimer's clinical trials located in New York?
Study sites for the Alzheimer's trials listed on this page include New York, Staten Island, Brooklyn. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Alzheimer's clinical trial in New York?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Alzheimer's trials in New York also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Alzheimer's clinical trial in New York?
Each study sets its own criteria based on age, Alzheimer's diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need an Alzheimer's diagnosis to join a trial?
No. Prevention trials enroll people with normal memory and test them for early amyloid, and many treatment trials accept people with memory concerns who have not been formally diagnosed, then confirm the diagnosis as part of screening.
What is a study partner?
A family member or close friend who attends visits with you and answers questions about memory and daily activities. Nearly every Alzheimer's trial requires one, and their time is usually reimbursed too.
Will I learn my amyloid or APOE results?
Many trials now disclose amyloid status, since it decides eligibility, and explain what it means. Genetic results are disclosed in some trials and not others; ask before you consent.
Alzheimer's Trials in Other States
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Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
All guides →
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
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About Alzheimer's Trials
Alzheimer's disease trials test amyloid-clearing antibodies, tau inhibitors, lifestyle interventions, and early-detection biomarkers for dementia prevention and treatment.
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