14 Recruiting Trials

Clinical Trials
for Alzheimer's in Virginia

14 clinical trials for Alzheimer's are currently recruiting participants at study sites in Virginia. Study-related care is provided at no cost.

14
Recruiting trials
15
Study sites
9
Cities
9
Industry-sponsored
5
Phase 2
6
Phase 3

Alzheimer's clinical trials in Virginia: what to expect

Alzheimer's trials now span the whole course of the disease. Prevention studies enroll people with normal memory who have early signs of amyloid in the brain; treatment studies enroll people with mild cognitive impairment or early Alzheimer's and test the next generation of antibodies, tau-targeting drugs and combinations; and symptom studies address agitation, sleep and depression in later stages. Alongside drugs there are trials of exercise, cognitive training, blood tests for diagnosis and support programs for care partners.

In Virginia, recruiting alzheimer's studies are concentrated in Fairfax, Arlington, Richmond and Charlottesville, with sites in 5 other cities. 9 of the 14 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who Alzheimer's trials usually look for

Most drug trials enroll ages 50 to 85 and define a stage with a memory test score range, then confirm Alzheimer's with an amyloid PET scan, a spinal fluid test or, increasingly, a blood test, all done by the study. Nearly every trial requires a study partner: someone who knows you well, attends visits and answers questions about daily life. Common exclusions are another cause of memory loss, a recent stroke and, for antibody trials, some blood thinners or MRI findings. Prevention trials enroll people with no symptoms at all.

What taking part involves

Screening is longer than for most conditions, often several visits over a few weeks with memory testing, an MRI and an amyloid test. Antibody trials then involve an infusion or injection every two to four weeks, regular safety MRIs and visits for eighteen months to four years, with an extension in which everyone receives the drug. Lifestyle trials involve classes or coaching for six to twenty-four months. All study care is free and travel is usually reimbursed for you and your partner.

Questions worth asking the study team

Whether you will be told your amyloid or genetic results; what the MRI safety monitoring involves; how much time the study partner must give; whether there is an extension after the placebo period; and what happens if memory worsens during the study.

Showing 14 of 14 recruiting Alzheimer's trials in Virginia

A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease
PHASE3 Irvine, California +4 sites NCT07717411
This trial is looking for people who show signs of Alzheimer's disease but are currently not experiencing cognitive impairment. Participants will receive treatment and help researchers understand its effects on preventing further progression of Alzheimer's.
Recruiting
Open-label Extension Study in Participants With Early Alzheimer's Disease
PHASE2 Maitland, Florida +4 sites NCT07105709
This trial is looking for people with early Alzheimer's disease who have completed a previous study. Participants will receive the study medicine GSK4527226 and help researchers learn about its long-term safety and effectiveness.
Recruiting
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
PHASE3 Birmingham, Alabama +4 sites NCT07177352
This trial is looking for individuals who may qualify for Alzheimer's disease research studies. Participants will be assessed to see if they can join related interventional studies.
Recruiting
Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)
PHASE3 Homewood, Alabama +4 sites NCT05980949
This trial is looking for people who have completed previous studies on KarXT for Alzheimer's-related psychosis. Participants will take KarXT for a year to help researchers understand its long-term safety and tolerability.
Recruiting
A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
PHASE3 Birmingham, Alabama +4 sites NCT07169578
This trial is looking for people with early Alzheimer's disease symptoms. Participants will take part in tests to evaluate their memory and cognitive abilities while receiving treatment.
Recruiting
A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
PHASE3 Phoenix, Arizona +4 sites NCT07170150
This trial is looking for people with early symptoms of Alzheimer's disease. Participants will take a medication called trontinemab and go through tests like imaging and assessments to see how well the treatment works and if it is safe.
Recruiting
Randomized Controlld Trial of Dementia Education Resources for Action
NA Fairfax, Virginia NCT07545577
This trial is looking for community health workers to take part in an online training program about Alzheimer’s disease and related dementias. Participants will help improve their knowledge and confidence in serving people affected by these conditions.
Recruiting
A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
PHASE3 Chandler, Arizona +4 sites NCT06585787
This trial is looking for adults aged 55 to 90 who have been diagnosed with Alzheimer's disease and have experienced troubling symptoms like hallucinations or delusions for at least two months. However, if someone has severe mental health issues like schizophrenia or major depression with psychosis, they won’t be eligible to join. They also need to have had a brain scan in the last five years to ensure there aren’t other serious conditions affecting their symptoms.
Recruiting
Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease
PHASE2 Phoenix, Arizona +4 sites NCT06847321
This trial is looking for people with mild to moderate Alzheimer's who also have a specific infection. Participants will take a daily capsule and attend study visits over 64 weeks.
Recruiting
Clinical Trial on Agitation in Alzheimer's Dementia
PHASE2 Maitland, Florida +4 sites NCT05543681
This trial is looking for people with Alzheimer's who experience agitation. Participants will take a THC-based medication twice a day and will be monitored for its effects.
Recruiting
Effects of THC-Free CBD Oil on Agitation in Patients With Alzheimer's Disease
PHASE2 Norfolk, Virginia NCT04436081
This trial is looking for people over 50 with Alzheimer's-related agitation. Participants will receive CBD oil to see if it helps reduce agitation and improve their quality of life.
Recruiting
Sleep Healthy Using the Internet Mitigating Insomnia to Address Neurocognitive Difficulties (SHUTi MIND)
PHASE2 Charlottesville, Virginia NCT05565833
This trial is looking for older adults with sleep problems and mild cognitive impairment. Participants will receive online therapy for insomnia or education about sleep to see how it affects their sleep and thinking.
Recruiting
The Role of the Locus Coeruleus in Age-related Distractibility
NA Blacksburg, Virginia NCT05574634
This trial is looking for healthy adults aged 18 to 75 who want to help research on attention in older adults. Participants will take part in cognitive training to see if it can improve their ability to focus.
Recruiting
Comparing Structured Retrieval Practice and Reading-Based Education for Dementia Caregivers
NA Virginia Beach, Virginia NCT07413406
This trial is looking for family caregivers of people living with dementia. Participants will learn care and self-care strategies using different educational approaches and share their experiences over time.
Recruiting

Where the Alzheimer's studies are in Virginia

  • Sana Research, LLC, Arlington3 trials
  • National Clinical Research Inc.-Richmond, Richmond2 trials
  • Re:Cognition Health, Fairfax2 trials
  • Conquest Research, LLC - Virginia - Vienna, Vienna1 trial
  • Dominion Medical Associates, Inc., Richmond1 trial
  • Eastern Virginia Medical School, Norfolk1 trial

Counts are recruiting studies listing at least one site in Virginia, from ClinicalTrials.gov, refreshed every two days.

Alzheimer's clinical trials in Virginia: common questions

How many Alzheimer's clinical trials are recruiting in Virginia?
TrialFinder currently lists 14 recruiting Alzheimer's clinical trials with study sites in Virginia. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Alzheimer's clinical trials located in Virginia?
Study sites for the Alzheimer's trials listed on this page include Fairfax, Norfolk, Charlottesville, Blacksburg, Virginia Beach. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Alzheimer's clinical trial in Virginia?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Alzheimer's trials in Virginia also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Alzheimer's clinical trial in Virginia?
Each study sets its own criteria based on age, Alzheimer's diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need an Alzheimer's diagnosis to join a trial?
No. Prevention trials enroll people with normal memory and test them for early amyloid, and many treatment trials accept people with memory concerns who have not been formally diagnosed, then confirm the diagnosis as part of screening.
What is a study partner?
A family member or close friend who attends visits with you and answers questions about memory and daily activities. Nearly every Alzheimer's trial requires one, and their time is usually reimbursed too.
Will I learn my amyloid or APOE results?
Many trials now disclose amyloid status, since it decides eligibility, and explain what it means. Genetic results are disclosed in some trials and not others; ask before you consent.
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
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Alzheimer's disease trials test amyloid-clearing antibodies, tau inhibitors, lifestyle interventions, and early-detection biomarkers for dementia prevention and treatment.

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