17 Recruiting Trials

Clinical Trials
for Alzheimer's in Washington

17 clinical trials for Alzheimer's are currently recruiting participants at study sites in Washington. Study-related care is provided at no cost.

17
Recruiting trials
11
Study sites
6
Cities
11
Industry-sponsored
6
Phase 2
9
Phase 3

Alzheimer's clinical trials in Washington: what to expect

Alzheimer's trials now span the whole course of the disease. Prevention studies enroll people with normal memory who have early signs of amyloid in the brain; treatment studies enroll people with mild cognitive impairment or early Alzheimer's and test the next generation of antibodies, tau-targeting drugs and combinations; and symptom studies address agitation, sleep and depression in later stages. Alongside drugs there are trials of exercise, cognitive training, blood tests for diagnosis and support programs for care partners.

In Washington, recruiting alzheimer's studies are concentrated in Seattle, Bellevue, Kirkland and Renton, with sites in 2 other cities. 11 of the 17 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who Alzheimer's trials usually look for

Most drug trials enroll ages 50 to 85 and define a stage with a memory test score range, then confirm Alzheimer's with an amyloid PET scan, a spinal fluid test or, increasingly, a blood test, all done by the study. Nearly every trial requires a study partner: someone who knows you well, attends visits and answers questions about daily life. Common exclusions are another cause of memory loss, a recent stroke and, for antibody trials, some blood thinners or MRI findings. Prevention trials enroll people with no symptoms at all.

What taking part involves

Screening is longer than for most conditions, often several visits over a few weeks with memory testing, an MRI and an amyloid test. Antibody trials then involve an infusion or injection every two to four weeks, regular safety MRIs and visits for eighteen months to four years, with an extension in which everyone receives the drug. Lifestyle trials involve classes or coaching for six to twenty-four months. All study care is free and travel is usually reimbursed for you and your partner.

Questions worth asking the study team

Whether you will be told your amyloid or genetic results; what the MRI safety monitoring involves; how much time the study partner must give; whether there is an extension after the placebo period; and what happens if memory worsens during the study.

Showing 17 of 17 recruiting Alzheimer's trials in Washington

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
PHASE3 Fullerton, California +4 sites NCT06976203
This trial is looking for people with Alzheimer's disease who are experiencing cognitive impairment. Participants will take the medications KarXT and KarX-EC and attend scheduled visits with a caregiver throughout the study.
Recruiting
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease
PHASE3 Chandler, Arizona +4 sites NCT07011745
This trial is looking for adults with agitation related to Alzheimer's Disease. Participants will receive a treatment and will be asked to have their caregiver attend visits and help with the study.
Recruiting
A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease
PHASE2 Phoenix, Arizona +4 sites NCT07094516
This trial is looking for people aged 50 to 85 with early Alzheimer's disease. Participants will take VHB937 for up to 72 weeks and will have regular visits with a study partner.
Recruiting
Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)
PHASE3 Homewood, Alabama +4 sites NCT05980949
This trial is looking for people who have completed previous studies on KarXT for Alzheimer's-related psychosis. Participants will take KarXT for a year to help researchers understand its long-term safety and tolerability.
Recruiting
A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
PHASE2 Birmingham, Alabama +4 sites NCT05552157
This trial is looking for adults aged 18 and older who have a specific genetic mutation linked to early Alzheimer's disease or have a family history of it, but are not showing any signs of cognitive decline yet. They also ask that women who could become pregnant use effective birth control during the study. If someone has significant health issues or cannot communicate in the approved language, they won’t be able to participate.
Recruiting
A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
PHASE2 Birmingham, Alabama +4 sites NCT06647498
This trial is looking for adults at risk for Alzheimer's disease caused by genetic mutations. If eligible, I will take a study drug and undergo various tests to help assess its effects on the disease.
Recruiting
A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis
PHASE2 Phoenix, Arizona +4 sites NCT06887192
This trial is looking for men and women aged 55 to 90 who have Alzheimer's disease and are experiencing symptoms like hallucinations or delusions. They need to have been living in the same place for at least six weeks and have a support person who can help track their health. However, it’s important to note that people who are seriously ill, have other major medical issues, or have substance abuse problems can't participate.
Recruiting
Dominantly Inherited Alzheimer Network (DIAN)
N/A Jacksonville, Florida +4 sites NCT00869817
This trial is looking for adults who are children of someone with Alzheimer's disease and have not shown symptoms themselves. Participants will help researchers find signs that might predict who will develop Alzheimer's disease in the future.
Recruiting
A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis Associated With Alzheimer's Disease
PHASE2 Anaheim, California +4 sites NCT06540833
This trial is looking for adults with Alzheimer's disease who are experiencing symptoms like delusions or hallucinations. They need to be able to understand what the study involves and have a caregiver to help them. However, individuals with certain serious mental health issues, recent suicide attempts, or those who are very ill or in hospice care cannot participate.
Recruiting
Development of Measures to Screen for Financial Hardship in Alzheimer's Disease and Dementia
N/A Seattle, Washington NCT06922188
This trial is looking for adults who have Alzheimer's disease or are caregivers for someone with the disease. Participants will help develop tools to identify financial difficulties faced by patients and their caregivers.
Recruiting
A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)
PHASE3 Chandler, Arizona +4 sites NCT06937229
This trial is looking for people with agitation related to Alzheimer's Disease who have completed earlier studies. Participants will take a combination of two specific medications to see how well they work over time and if they are safe.
Recruiting
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)
PHASE3 Scottsdale, Arizona +4 sites NCT07011732
This trial is looking for adults with Alzheimer's disease who experience agitation. Participants will take the study medication and have regular visits to assess their condition.
Recruiting
A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
PHASE3 Chandler, Arizona +4 sites NCT06585787
This trial is looking for adults aged 55 to 90 who have been diagnosed with Alzheimer's disease and have experienced troubling symptoms like hallucinations or delusions for at least two months. However, if someone has severe mental health issues like schizophrenia or major depression with psychosis, they won’t be eligible to join. They also need to have had a brain scan in the last five years to ensure there aren’t other serious conditions affecting their symptoms.
Recruiting
Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease
PHASE2 Phoenix, Arizona +4 sites NCT06847321
This trial is looking for people with mild to moderate Alzheimer's who also have a specific infection. Participants will take a daily capsule and attend study visits over 64 weeks.
Recruiting
Late Onset Alzheimer's Disease
N/A Washington D.C., District of Columbia +4 sites NCT05010603
This trial is looking for families or individuals with a history of Alzheimer's Disease. Participants will provide information about their family health history to help researchers understand the genetic factors of the disease.
Recruiting
A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors
NA Seattle, Washington NCT06411561
This trial is looking for older adults who have spent time in an ICU and are recovering from critical illness. Participants will take part in activities to improve their thinking skills and sleep.
Recruiting
A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).
PHASE3 Phoenix, Arizona +4 sites NCT07602582
This trial is looking for people who have previously participated in a related study and who want to see if they benefit from yearly doses of donanemab. Participants will attend up to 6 visits during the study, which lasts up to 2.5 years.
Recruiting

Where the Alzheimer's studies are in Washington

  • University of Washington, Seattle5 trials
  • Northwest Clinical Research Center, Bellevue4 trials
  • Local Institution - 1254, Kirkland2 trials
  • Local Institution - 1644, Seattle2 trials
  • Clinical Site, Bellevue1 trial
  • EvergreenHealth Medical Center, Kirkland1 trial

Counts are recruiting studies listing at least one site in Washington, from ClinicalTrials.gov, refreshed every two days.

Alzheimer's clinical trials in Washington: common questions

How many Alzheimer's clinical trials are recruiting in Washington?
TrialFinder currently lists 17 recruiting Alzheimer's clinical trials with study sites in Washington. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Alzheimer's clinical trials located in Washington?
Study sites for the Alzheimer's trials listed on this page include Seattle. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Alzheimer's clinical trial in Washington?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Alzheimer's trials in Washington also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Alzheimer's clinical trial in Washington?
Each study sets its own criteria based on age, Alzheimer's diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need an Alzheimer's diagnosis to join a trial?
No. Prevention trials enroll people with normal memory and test them for early amyloid, and many treatment trials accept people with memory concerns who have not been formally diagnosed, then confirm the diagnosis as part of screening.
What is a study partner?
A family member or close friend who attends visits with you and answers questions about memory and daily activities. Nearly every Alzheimer's trial requires one, and their time is usually reimbursed too.
Will I learn my amyloid or APOE results?
Many trials now disclose amyloid status, since it decides eligibility, and explain what it means. Genetic results are disclosed in some trials and not others; ask before you consent.
Are Clinical Trials Safe? What Patients Should Know
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How to Know If You Qualify for a Clinical Trial
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Clinical Trials Without Insurance: What You Need to Know
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Alzheimer's disease trials test amyloid-clearing antibodies, tau inhibitors, lifestyle interventions, and early-detection biomarkers for dementia prevention and treatment.

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