62 Recruiting Trials

Clinical Trials
for Alzheimer's in Florida

62 clinical trials for Alzheimer's are currently recruiting participants at study sites in Florida. Study-related care is provided at no cost.

62
Recruiting trials
345
Study sites
56
Cities
49
Industry-sponsored
20
Phase 2
17
Phase 3

Alzheimer's clinical trials in Florida: what to expect

Alzheimer's trials now span the whole course of the disease. Prevention studies enroll people with normal memory who have early signs of amyloid in the brain; treatment studies enroll people with mild cognitive impairment or early Alzheimer's and test the next generation of antibodies, tau-targeting drugs and combinations; and symptom studies address agitation, sleep and depression in later stages. Alongside drugs there are trials of exercise, cognitive training, blood tests for diagnosis and support programs for care partners.

In Florida, recruiting alzheimer's studies are concentrated in Miami, Maitland, Tampa and Orlando, with sites in 52 other cities. 49 of the 62 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who Alzheimer's trials usually look for

Most drug trials enroll ages 50 to 85 and define a stage with a memory test score range, then confirm Alzheimer's with an amyloid PET scan, a spinal fluid test or, increasingly, a blood test, all done by the study. Nearly every trial requires a study partner: someone who knows you well, attends visits and answers questions about daily life. Common exclusions are another cause of memory loss, a recent stroke and, for antibody trials, some blood thinners or MRI findings. Prevention trials enroll people with no symptoms at all.

What taking part involves

Screening is longer than for most conditions, often several visits over a few weeks with memory testing, an MRI and an amyloid test. Antibody trials then involve an infusion or injection every two to four weeks, regular safety MRIs and visits for eighteen months to four years, with an extension in which everyone receives the drug. Lifestyle trials involve classes or coaching for six to twenty-four months. All study care is free and travel is usually reimbursed for you and your partner.

Questions worth asking the study team

Whether you will be told your amyloid or genetic results; what the MRI safety monitoring involves; how much time the study partner must give; whether there is an extension after the placebo period; and what happens if memory worsens during the study.

Showing 20 of 62 recruiting Alzheimer's trials in Florida

A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease
PHASE3 Maitland, Florida +4 sites NCT07717411
This trial is looking for people who show signs of Alzheimer's disease but are currently not experiencing cognitive impairment. Participants will receive treatment and help researchers understand its effects on preventing further progression of Alzheimer's.
Recruiting
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
PHASE3 Fullerton, California +4 sites NCT06976203
This trial is looking for people with Alzheimer's disease who are experiencing cognitive impairment. Participants will take the medications KarXT and KarX-EC and attend scheduled visits with a caregiver throughout the study.
Recruiting
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease
PHASE3 Chandler, Arizona +4 sites NCT07011745
This trial is looking for adults with agitation related to Alzheimer's Disease. Participants will receive a treatment and will be asked to have their caregiver attend visits and help with the study.
Recruiting
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
PHASE3 Atlantis, Florida +4 sites NCT06976216
This trial is looking for people with mild to moderate Alzheimer's disease who want to help test a new treatment. Participants will need a caregiver to support them and attend study visits.
Recruiting
A Study to Investigate the Safety and Effectiveness of SAR448851 in Participants With Early Alzheimer's Disease
PHASE2 Naples, Florida +4 sites NCT07688213
This trial is looking for people aged 55 to 85 with mild Alzheimer's disease or mild cognitive impairment. Participants will take a daily pill and might continue in the study for up to 111 weeks.
Recruiting
A Study to Assess the Safety and Effects of ABBV-1758 Following Subcutaneous or Intravenous Injections in Participants With Alzheimer's Disease
PHASE1 Bradenton, Florida +4 sites NCT07599670
This trial is looking for people with Alzheimer's disease to test a new drug called ABBV-1758. Participants will receive injections of the drug or a placebo every 4 weeks for 24 weeks.
Recruiting
A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease
PHASE2 Atlantis, Florida +4 sites NCT07094516
This trial is looking for people aged 50 to 85 with early Alzheimer's disease. Participants will take VHB937 for up to 72 weeks and will have regular visits with a study partner.
Recruiting
Open-label Extension Study in Participants With Early Alzheimer's Disease
PHASE2 Maitland, Florida +4 sites NCT07105709
This trial is looking for people with early Alzheimer's disease who have completed a previous study. Participants will receive the study medicine GSK4527226 and help researchers learn about its long-term safety and effectiveness.
Recruiting
A Study to Evaluate the Drug Levels, Absolute Bioavailability, Safety, Tolerability, and Immunogenicity of Single-Dose of BMS-986446 in Healthy Adults After Single-dose Administration, and Participants With Early Alzheimer's Disease After Multiple Dose Administration
PHASE1 Bradenton, Florida +4 sites NCT07780383
This trial is looking for healthy adults and people with early Alzheimer's disease. Participants will take a single or multiple doses of the drug BMS-986446 to help researchers understand its effects and safety.
Recruiting
ACP-204 in Adults With Alzheimer's Disease Psychosis
PHASE2 Chandler, Arizona +4 sites NCT06159673
This trial is looking for adults aged 55 to 95 who have Alzheimer's disease psychosis. Participants will receive either ACP-204 or a placebo for six weeks, with follow-up visits to check on their health afterwards.
Recruiting
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
PHASE3 Birmingham, Alabama +4 sites NCT07177352
This trial is looking for individuals who may qualify for Alzheimer's disease research studies. Participants will be assessed to see if they can join related interventional studies.
Recruiting
Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)
PHASE3 Homewood, Alabama +4 sites NCT05980949
This trial is looking for people who have completed previous studies on KarXT for Alzheimer's-related psychosis. Participants will take KarXT for a year to help researchers understand its long-term safety and tolerability.
Recruiting
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)
PHASE3 Chandler, Arizona +4 sites NCT06126224
This trial is looking for men and women aged 55 to 90 who have Alzheimer's disease along with symptoms like hallucinations or delusions. They need to have a stable living situation and a trusted person who sees them regularly. However, people with certain other mental health conditions or serious medical issues will not be eligible to participate.
Recruiting
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)
PHASE3 Homewood, Alabama +4 sites NCT05511363
This trial is looking for older adults with psychosis associated with Alzheimer's Disease. Participants will be randomly assigned to receive either KarXT or a placebo for 38 weeks, with regular visits to monitor their condition.
Recruiting
A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
PHASE3 Birmingham, Alabama +4 sites NCT07169578
This trial is looking for people with early Alzheimer's disease symptoms. Participants will take part in tests to evaluate their memory and cognitive abilities while receiving treatment.
Recruiting
A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
PHASE3 Phoenix, Arizona +4 sites NCT07170150
This trial is looking for people with early symptoms of Alzheimer's disease. Participants will take a medication called trontinemab and go through tests like imaging and assessments to see how well the treatment works and if it is safe.
Recruiting
A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)
PHASE2 Irvine, California +4 sites NCT07033494
This trial is looking for people with early Alzheimer's disease who want to help researchers learn if a new treatment called MK-2214 can help slow down brain changes. Participants will take MK-2214 or a placebo and be monitored for safety and effects.
Recruiting
A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis
PHASE2 Phoenix, Arizona +4 sites NCT06887192
This trial is looking for men and women aged 55 to 90 who have Alzheimer's disease and are experiencing symptoms like hallucinations or delusions. They need to have been living in the same place for at least six weeks and have a support person who can help track their health. However, it’s important to note that people who are seriously ill, have other major medical issues, or have substance abuse problems can't participate.
Recruiting
A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Agitation Associated With Alzheimer's Dementia
PHASE2 Boca Raton, Florida +4 sites NCT06651567
This trial is looking for people with agitation related to Alzheimer's dementia. Participants will receive either the study drug ITI-1284 or a placebo to assess its effectiveness and safety.
Recruiting

Where the Alzheimer's studies are in Florida

  • K2 Medical Research, Maitland8 trials
  • Progressive Medical Research, Port Orange8 trials
  • Arrow Clinical Trials, Daytona Beach6 trials
  • Envision Trials LLC, Bonita Springs5 trials
  • K2 Medical Research, LLC, Maitland5 trials
  • Renstar Medical Research, Ocala5 trials

Counts are recruiting studies listing at least one site in Florida, from ClinicalTrials.gov, refreshed every two days.

Alzheimer's clinical trials in Florida: common questions

How many Alzheimer's clinical trials are recruiting in Florida?
TrialFinder currently lists 62 recruiting Alzheimer's clinical trials with study sites in Florida. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Alzheimer's clinical trials located in Florida?
Study sites for the Alzheimer's trials listed on this page include Maitland, Atlantis, Naples, Bradenton, Boca Raton. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Alzheimer's clinical trial in Florida?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Alzheimer's trials in Florida also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Alzheimer's clinical trial in Florida?
Each study sets its own criteria based on age, Alzheimer's diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need an Alzheimer's diagnosis to join a trial?
No. Prevention trials enroll people with normal memory and test them for early amyloid, and many treatment trials accept people with memory concerns who have not been formally diagnosed, then confirm the diagnosis as part of screening.
What is a study partner?
A family member or close friend who attends visits with you and answers questions about memory and daily activities. Nearly every Alzheimer's trial requires one, and their time is usually reimbursed too.
Will I learn my amyloid or APOE results?
Many trials now disclose amyloid status, since it decides eligibility, and explain what it means. Genetic results are disclosed in some trials and not others; ask before you consent.
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
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Alzheimer's disease trials test amyloid-clearing antibodies, tau inhibitors, lifestyle interventions, and early-detection biomarkers for dementia prevention and treatment.

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