19 Recruiting Trials
Clinical Trials
for Alzheimer's in Michigan
19 clinical trials for Alzheimer's are currently recruiting participants at study sites in Michigan. Study-related care is provided at no cost.
19
Recruiting trials
17
Study sites
11
Cities
18
Industry-sponsored
2
Phase 2
11
Phase 3
Alzheimer's clinical trials in Michigan: what to expect
Alzheimer's trials now span the whole course of the disease. Prevention studies enroll people with normal memory who have early signs of amyloid in the brain; treatment studies enroll people with mild cognitive impairment or early Alzheimer's and test the next generation of antibodies, tau-targeting drugs and combinations; and symptom studies address agitation, sleep and depression in later stages. Alongside drugs there are trials of exercise, cognitive training, blood tests for diagnosis and support programs for care partners.
In Michigan, recruiting alzheimer's studies are concentrated in Farmington Hills, Rochester Hills, Ann Arbor and Bloomfield Township, with sites in 7 other cities. 18 of the 19 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.
Who Alzheimer's trials usually look for
Most drug trials enroll ages 50 to 85 and define a stage with a memory test score range, then confirm Alzheimer's with an amyloid PET scan, a spinal fluid test or, increasingly, a blood test, all done by the study. Nearly every trial requires a study partner: someone who knows you well, attends visits and answers questions about daily life. Common exclusions are another cause of memory loss, a recent stroke and, for antibody trials, some blood thinners or MRI findings. Prevention trials enroll people with no symptoms at all.
What taking part involves
Screening is longer than for most conditions, often several visits over a few weeks with memory testing, an MRI and an amyloid test. Antibody trials then involve an infusion or injection every two to four weeks, regular safety MRIs and visits for eighteen months to four years, with an extension in which everyone receives the drug. Lifestyle trials involve classes or coaching for six to twenty-four months. All study care is free and travel is usually reimbursed for you and your partner.
Questions worth asking the study team
Whether you will be told your amyloid or genetic results; what the MRI safety monitoring involves; how much time the study partner must give; whether there is an extension after the placebo period; and what happens if memory worsens during the study.
Showing 19 of 19 recruiting Alzheimer's trials in Michigan
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
Recruiting
This trial is looking for people with Alzheimer's disease who are experiencing cognitive impairment. Participants will take the medications KarXT and KarX-EC and attend scheduled visits with a caregiver throughout the study.
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease
Recruiting
This trial is looking for adults with agitation related to Alzheimer's Disease. Participants will receive a treatment and will be asked to have their caregiver attend visits and help with the study.
ACP-204 in Adults With Alzheimer's Disease Psychosis
Recruiting
This trial is looking for adults aged 55 to 95 who have Alzheimer's disease psychosis. Participants will receive either ACP-204 or a placebo for six weeks, with follow-up visits to check on their health afterwards.
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
Recruiting
This trial is looking for individuals who may qualify for Alzheimer's disease research studies. Participants will be assessed to see if they can join related interventional studies.
Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)
Recruiting
This trial is looking for people who have completed previous studies on KarXT for Alzheimer's-related psychosis. Participants will take KarXT for a year to help researchers understand its long-term safety and tolerability.
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)
Recruiting
This trial is looking for men and women aged 55 to 90 who have Alzheimer's disease along with symptoms like hallucinations or delusions. They need to have a stable living situation and a trusted person who sees them regularly. However, people with certain other mental health conditions or serious medical issues will not be eligible to participate.
A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
Recruiting
This trial is looking for people with early symptoms of Alzheimer's disease. Participants will take a medication called trontinemab and go through tests like imaging and assessments to see how well the treatment works and if it is safe.
Development of a Home Test for Measuring Blood P-tau217 in Alzheimer's Disease Using the Tasso Lancet Device
Recruiting
This trial is looking for people who either have Alzheimer's disease or don’t have it but have cognitive impairment. Participants will help compare blood samples collected at home to those taken in a clinic to measure a certain biomarker linked to Alzheimer's.
A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)
Recruiting
This trial is looking for people with agitation related to Alzheimer's Disease who have completed earlier studies. Participants will take a combination of two specific medications to see how well they work over time and if they are safe.
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)
Recruiting
This trial is looking for adults with Alzheimer's disease who experience agitation. Participants will take the study medication and have regular visits to assess their condition.
A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
Recruiting
This trial is looking for adults aged 55 to 90 who have been diagnosed with Alzheimer's disease and have experienced troubling symptoms like hallucinations or delusions for at least two months. However, if someone has severe mental health issues like schizophrenia or major depression with psychosis, they won’t be eligible to join. They also need to have had a brain scan in the last five years to ensure there aren’t other serious conditions affecting their symptoms.
Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease
Recruiting
This trial is looking for people with Alzheimer's disease who experience agitation. Participants will take a medication called BMS-986368 and help researchers understand its effects.
A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)
Recruiting
This trial is looking for adults aged 50 and older who have been diagnosed with mild to moderate Alzheimer's disease. Participants will take Zunveyl for 12 weeks and will be monitored for safety and side effects.
A Master Protocol Studying Multiple Amyloid-Targeting Therapies in Healthy Participants and Participants With Alzheimer's Disease
Recruiting
This trial is looking for healthy individuals and people with Alzheimer's disease to test the safety of different treatments. Participants will receive either one of two drugs and undergo tests to see if the treatments remove protein clumps in the brain.
A Study of LY3439539 in Participants With Alzheimer's Disease
Recruiting
This trial is looking for people with Alzheimer's disease to see how LY3439539 affects certain proteins in their spinal fluid. If you join, you will have monthly visits for about 9 months.
A Study of LY4006895 in Healthy Participants With Early Symptomatic Alzheimer's Disease (AD)
Recruiting
This trial is looking for healthy adults and participants with early symptoms of Alzheimer's disease. Those who join will take a study drug called LY4006895 and undergo various health checks over several months.
Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia
Recruiting
This trial is looking for older adults who are cognitively normal, have mild cognitive impairment, or mild to moderate Alzheimer's disease. Participants will undergo various tests, including blood samples and brain scans, to help understand the connections between different markers and brain changes in Alzheimer's.
A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).
Recruiting
This trial is looking for people who have previously participated in a related study and who want to see if they benefit from yearly doses of donanemab. Participants will attend up to 6 visits during the study, which lasts up to 2.5 years.
Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders
Recruiting
This trial is looking for older adults who are at least 70 years old and are expected to be in the hospital for at least three days. They should have some risks for confusion, like trouble thinking or seeing, and need to have a family member or caregiver who can be with them in the hospital. However, it won’t include anyone who is already confused when they arrive or can't communicate clearly.
Where the Alzheimer's studies are in Michigan
Research sites running the most studies
- QUEST Research Institute, Farmington Hills4 trials
- Quest Research Institute, Farmington Hills4 trials
- Local Institution - 1139, Rochester Hills2 trials
- Insight Hospital and Medical Center Dearborn, Dearborn1 trial
- Insight Institute of Neurology and Neurosurgery, Flint1 trial
- Khan Revive Research Institute, Rochester Hills1 trial
By city
Counts are recruiting studies listing at least one site in Michigan, from ClinicalTrials.gov, refreshed every two days.
Alzheimer's clinical trials in Michigan: common questions
How many Alzheimer's clinical trials are recruiting in Michigan?
TrialFinder currently lists 19 recruiting Alzheimer's clinical trials with study sites in Michigan. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Alzheimer's clinical trials located in Michigan?
Study sites for the Alzheimer's trials listed on this page include Dearborn, Ann Arbor. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Alzheimer's clinical trial in Michigan?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Alzheimer's trials in Michigan also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Alzheimer's clinical trial in Michigan?
Each study sets its own criteria based on age, Alzheimer's diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need an Alzheimer's diagnosis to join a trial?
No. Prevention trials enroll people with normal memory and test them for early amyloid, and many treatment trials accept people with memory concerns who have not been formally diagnosed, then confirm the diagnosis as part of screening.
What is a study partner?
A family member or close friend who attends visits with you and answers questions about memory and daily activities. Nearly every Alzheimer's trial requires one, and their time is usually reimbursed too.
Will I learn my amyloid or APOE results?
Many trials now disclose amyloid status, since it decides eligibility, and explain what it means. Genetic results are disclosed in some trials and not others; ask before you consent.
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Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
All guides →
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
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About Alzheimer's Trials
Alzheimer's disease trials test amyloid-clearing antibodies, tau inhibitors, lifestyle interventions, and early-detection biomarkers for dementia prevention and treatment.
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