15 Recruiting Trials

Clinical Trials
for Kidney Disease in Virginia

15 clinical trials for Kidney Disease are currently recruiting participants at study sites in Virginia. Study-related care is provided at no cost.

15
Recruiting trials
26
Study sites
12
Cities
10
Industry-sponsored
4
Phase 2
9
Phase 3

Kidney Disease clinical trials in Virginia: what to expect

Kidney disease trials are mostly for chronic kidney disease that is slowly getting worse, including kidney disease caused by diabetes. They test medicines meant to slow the decline in kidney function and protect the heart, usually on top of the standard blood pressure and diabetes treatments. Specific kidney diseases such as IgA nephropathy, FSGS and polycystic kidney disease now have many trials of their own, and separate studies enroll people on dialysis or living with a transplant.

In Virginia, recruiting kidney disease studies are concentrated in Richmond, Arlington, Norfolk and Charlottesville, with sites in 8 other cities. 10 of the 15 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who kidney disease trials usually look for

Trials describe kidney disease by two numbers: the filtration rate (eGFR) from a blood test and the amount of protein in the urine. Most enroll an eGFR between about 20 and 75 and a urine protein level above a cut-off, both measured at screening. Nearly all ask that you have taken a stable dose of a blood-pressure medicine of the ACE inhibitor or ARB type for three months, and many allow or require an SGLT2 inhibitor. IgA nephropathy and FSGS trials need a past kidney biopsy. Common exclusions are a transplant, dialysis and uncontrolled blood pressure.

What taking part involves

Screening includes blood and urine tests, sometimes a 24-hour urine collection, and a review of your records. Trials then run one to three years with visits every four to twelve weeks for labs and blood pressure, taking a study pill or injection added to your usual medicines; placebo arms are common and an extension often follows. Your nephrologist keeps managing your care. Study medicine and tests are free and visits are usually paid.

Questions worth asking the study team

Which stage the trial enrolls and whether you fit it; whether any of your medicines change; how often labs are needed; the chance of placebo; and whether you will be told your own kidney results during the study.

Showing 15 of 15 recruiting Kidney Disease trials in Virginia

A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)
PHASE3 Birmingham, Alabama +4 sites NCT07107945
This trial is looking for children aged 2 to 17 who have chronic kidney disease. Participants will take a daily tablet for 6 months followed by 1 year of another medication, with regular check-ups to monitor their health.
Recruiting
A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.
PHASE3 Huntsville, Alabama +4 sites NCT07753993
This trial is looking for adults with chronic kidney disease to see how well elecoglipron works compared to a placebo. Participants must be on certain medications for their condition before joining the study.
Recruiting
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
PHASE2 Decatur, Alabama +4 sites NCT05485961
This trial is looking for adults with end stage kidney disease who are undergoing dialysis and have systemic inflammation. Participants will receive a study medication or a placebo to see how it affects heart health.
Recruiting
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
PHASE3 Fairhope, Alabama +4 sites NCT06742723
This trial is looking for adults with chronic kidney disease and high blood pressure. If you join, you will take medications to see how they affect your kidney health and heart-related risks.
Recruiting
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
PHASE2 Alabaster, Alabama +4 sites NCT05312879
This trial is looking for adults and children with a specific type of kidney disease caused by genetics. Participants will receive the drug VX-147 to assess its effectiveness and safety.
Recruiting
A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease
PHASE2 Decatur, Alabama +4 sites NCT06830629
This trial is looking for adults with a specific genetic risk for kidney disease and ongoing protein in their urine. Participants will take the drug MZE829 to see how it affects their kidney condition.
Recruiting
A Study of Mezagitamab in Adults With Kidney Condition Called IgA Nephropathy
PHASE3 Birmingham, Alabama +4 sites NCT06963827
This trial is looking for adults with a kidney condition called IgA nephropathy. Participants will receive either mezagitamab or a placebo for 22 weeks and then be monitored for about 1.5 years.
Recruiting
Incremental Hemodialysis: The TwoPlus Trial
NA Jacksonville, Florida +4 sites NCT05828823
This trial is looking for adults with kidney problems who need dialysis. Participants will either start a new type of dialysis called incremental hemodialysis or a traditional one. The trial will follow them for about two years to compare the outcomes.
Recruiting
A Phase III Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With CKD Stage 3b and 4 (BalanceD-CKD)
PHASE3 Huntsville, Alabama +4 sites NCT07624305
This trial is looking for adults with chronic kidney disease stages 3b and 4. Participants will take a daily combination of two medications to see how well they work together compared to taking just one of them.
Recruiting
PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes
PHASE4 Huntsville, Alabama +4 sites NCT05390892
This trial is looking for people with type 2 diabetes and heart disease or at high risk for heart disease. Participants will take one of two medications and will be monitored for heart, kidney, and death-related events over time.
Recruiting
Randomized Trial of SGLT2i in Heart Transplant Recipients
PHASE4 Richmond, Virginia +4 sites NCT06625073
This trial is looking for heart transplant recipients who are at least 3 months post-surgery. Participants will take either empagliflozin or a placebo daily for 12 months to see how it affects their kidney function and overall health.
Recruiting
Kidney Transplant Preemptive Therapy or Prophylaxis for CMV Prevention in D+R Recipients
PHASE3 San Francisco, California +4 sites NCT06798909
This trial is looking for adults who have received a kidney transplant from a CMV positive donor. If you join, you will be randomly assigned to take either Valganciclovir or Letermovir for a specified time to help prevent a virus called CMV.
Recruiting
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin
PHASE3 Sun City, Arizona +4 sites NCT07662135
This trial is looking for adults with type 2 diabetes and kidney problems. Participants will take either elecoglipron or a placebo while continuing their diabetes medications.
Recruiting
A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia
PHASE2 Huntsville, Alabama +4 sites NCT06712654
This trial is looking for adults with high phosphate levels who are on dialysis. Participants will take a medication called AP306 while continuing their regular dialysis treatments.
Recruiting
Kidney Function in People With Cystic Fibrosis in the Era of HEMT
N/A Charlottesville, Virginia +2 sites NCT06595420
This trial is looking for people with cystic fibrosis to help understand kidney health. Participants will provide urine and blood samples to compare kidney markers over time.
Recruiting

Where the Kidney Disease studies are in Virginia

  • Research Site, Arlington4 trials
  • Research Site, Richmond2 trials
  • Research Site, Woodbridge2 trials
  • Research Site, Norfolk2 trials
  • DCR-Norfolk Great Bridge, Chesapeake1 trial
  • DaVita Clinical Research Norfolk, Norfolk1 trial

Counts are recruiting studies listing at least one site in Virginia, from ClinicalTrials.gov, refreshed every two days.

Kidney Disease clinical trials in Virginia: common questions

How many Kidney Disease clinical trials are recruiting in Virginia?
TrialFinder currently lists 15 recruiting Kidney Disease clinical trials with study sites in Virginia. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Kidney Disease clinical trials located in Virginia?
Study sites for the Kidney Disease trials listed on this page include Richmond, Charlottesville. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Kidney Disease clinical trial in Virginia?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Kidney Disease trials in Virginia also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Kidney Disease clinical trial in Virginia?
Each study sets its own criteria based on age, Kidney Disease diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
What stage of kidney disease do trials look for?
Trials state an eGFR range and a urine protein threshold rather than a stage name; most cover stages 2 to 4. People on dialysis or with a transplant have separate trials written for them.
Do I need a kidney biopsy to join?
Trials for IgA nephropathy, FSGS and lupus nephritis require a past biopsy confirming the diagnosis. Trials for diabetic or general chronic kidney disease do not.
Will I keep my current kidney and blood pressure medicines?
Yes. Kidney trials add the study treatment to a stable regimen, usually including an ACE inhibitor or ARB, and your own nephrologist continues to manage them.
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Kidney disease trials evaluate SGLT2 inhibitors, dialysis protocols, renal transplant regimens, and supportive-care strategies for chronic and acute kidney disease.

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