MitoQ for Improving Vascular Health After Stroke

MitoQ and Ischemic Conditioning To Assess Vascular Health Outcomes

Recruiting Phase 2 Interventional Study
Stroke
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 85
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Other
Participants needed
30 (estimated)
Sponsor
Medical College of Wisconsin · Other
Who this trial is looking for

This trial is looking for stroke survivors who want to improve their blood vessel function. Participants will try an antioxidant called MitoQ and a method called ischemic conditioning to see if these help with their recovery.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am 18 to 85 years old.
  • I had a stroke more than 6 months ago and have some weakness.
  • I can give informed consent and follow simple commands.
  • I speak English.

You may not be able to join if

  • I need help to stand up from a chair.
  • I have had blood clots or can't have compression on my legs.
  • I have had severe COVID-19 symptoms for more than 6 months.
  • I had a head injury in the past 6 months.
  • I have another neurological disorder.
  • I have peripheral vascular disease.
  • I had a heart attack or irregular heartbeat in the past year.
  • My resting blood pressure is too high.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer a few quick questions to see if you may meet the eligibility requirements.

Check Your Eligibility
About This Trial

Stroke survivors have compromised vascular function which may contribute to secondary stroke risk, cardiovascular disease, and may limit their exercise tolerance. Preliminary data shows a single bout of ischemic conditioning or oral ingestion of an over-the-counter antioxidant supplement called MitoQ may improve vascular function and muscle activity in individuals post-stroke.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * 18 - 85 years of age * Cortical or sub-cortical stroke ≥ 6 months ago with residual hemiparesis * Able to give informed consent and follow 2-step command. * English Speaking Exclusion Criteria: * Unable to stand from chair without physical assistance from another person (abl…
Contacts

Jennifer Nguyen

414-955-5713

jnguyen@mcw.edu

CONTACT

Alicen Whitaker-Hilbig, DPT, PhD

414-955-5713

awhitakerhilbig@mcw.edu

CONTACT