1166 Recruiting Trials

Clinical Trials
for Cancer in Texas

1166 clinical trials for Cancer are currently recruiting participants at study sites in Texas. Study-related care is provided at no cost.

1166
Recruiting trials
1180
Study sites
80
Cities
672
Industry-sponsored
443
Phase 2
227
Phase 3

Cancer clinical trials in Texas: what to expect

Cancer is the single largest area of clinical research, and nearly every recruiting cancer trial is written for one cancer type at one stage. Most test a new drug or combination against the current standard treatment: targeted medicines matched to a mutation found in the tumor, immunotherapies that help the immune system recognize cancer cells, antibody-drug conjugates and cell therapies. Others study surgery and radiation techniques, ways to reduce side effects, and screening or prevention in people at higher risk.

In Texas, recruiting cancer studies are concentrated in Houston, Dallas, San Antonio and Austin, with sites in 76 other cities. 672 of the 1166 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who cancer trials usually look for

Every listing names the cancer type and stage it enrolls, and most also state how many earlier treatments you may have had: some are for people newly diagnosed, many are for cancer that has come back or spread after a first treatment stopped working. Targeted-therapy trials require a specific result on tumor testing, which the site can arrange if it has not been done. Trials generally ask that you are well enough for daily activity (a "performance status" the doctor scores), that blood counts and liver and kidney function are adequate, and that a few weeks have passed since your last treatment.

Having advanced or metastatic cancer does not rule you out. A large share of recruiting trials are designed specifically for it.

What taking part involves

Screening reviews your pathology and scans, often with new blood work and sometimes a fresh biopsy. Treatment then follows a cycle, typically every two or three weeks, with scans every six to twelve weeks to measure the response. Early-phase trials have more frequent visits at the start. The study drug and study-specific tests are provided at no cost; standard care that you would receive anyway is usually billed to insurance as normal. A placebo on its own is rare in cancer trials: when there is one, it is added to the standard treatment, and the consent form says so.

Questions worth asking the study team

Whether the trial is randomized and what the comparison treatment is; what happens if the cancer grows during the study; whether you can keep receiving the drug afterward if it is working; how the trial fits with the plan your own oncologist has suggested; and what travel or lodging support is offered. Your oncologist can also refer you directly.

Showing 20 of 1166 recruiting Cancer trials in Texas

Pan Tumor Rollover Study
PHASE2 Huntsville, Alabama +4 sites NCT03899155
This trial is looking for patients with cancer who have had a good response to previous treatments. Participants will continue receiving nivolumab alone or in combination with other cancer therapies to study long-term safety.
Recruiting
Treatment of Immune Checkpoint Inhibitor-related Diarrhea and/ or Colitis With Ustekinumab in Cancer Patients
PHASE2 Houston, Texas NCT06807593
This trial is looking for cancer patients who have severe diarrhea or colitis caused by their immune therapy. Participants will be treated with a drug called ustekinumab to see if it helps improve their symptoms.
Recruiting
Selpercatinib Pre-RAI in Patients With RET Fusion Thyroid Cancer (RAISE)
PHASE2 Houston, Texas +4 sites NCT06458036
This trial is looking for young patients aged 2 to 25 who have been diagnosed with certain types of thyroid cancer and have had surgery. Participants will receive a treatment called selpercatinib before traditional radioactive iodine therapy.
Recruiting
ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors
PHASE1 Stanford, California +4 sites NCT03686124
This trial is looking for patients with certain types of cancer that keep coming back or do not respond to standard treatments. Participants will receive the study treatment IMA203/IMA203CD8, either alone or with nivolumab.
Recruiting
Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer
PHASE2 Houston, Texas +4 sites NCT05783323
This trial is looking for patients with differentiated thyroid cancer to take part in a study using the drug larotrectinib. Participants will need to meet certain health criteria and will be monitored during the treatment.
Recruiting
Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Cancer
PHASE2 Little Rock, Arkansas +4 sites NCT05997017
This trial is looking for women with advanced or recurrent endometrioid endometrial cancer to test a combination of two medications. Participants must have measurable disease and meet certain health criteria to join the study.
Recruiting
A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agents
PHASE1 Austin, Texas +3 sites NCT06090266
This trial is looking for adults with advanced solid tumors, like lung cancer or melanoma. Participants will receive a treatment called OR502 alone or with another cancer treatment to see how well it works and what side effects it has.
Recruiting
A Study in Patients With Advanced Cancers
PHASE1 Austin, Texas +2 sites NCT05320588
This trial is looking for patients with advanced cancers who have tried standard treatments without success. Participants will receive the study drug BIO-106, either alone or with another treatment called pembrolizumab.
Recruiting
A Phase 1 Study of IM-1617 in Participants With Advanced Cancer
PHASE1 Irving, Texas +3 sites NCT07578571
This trial is looking for people with advanced solid tumors that cannot be removed with surgery. Participants will receive a drug called IM-1617 to see how safe and effective it is.
Recruiting
Psycho-Spiritual Management for Patients With Advanced Cancer and Their Family Caregivers
NA Houston, Texas NCT06409065
This trial is looking for patients with certain types of advanced cancer and their family caregivers. Participants will take part in programs aimed at improving emotional wellbeing and overall quality of life.
Recruiting
Cancer-related Fatigue and Its Biological Contributors in Adolescent and Young Adult Brain Tumor Survivors: Effects of a Tele-exercise Intervention
NA Houston, Texas NCT07186556
This trial is looking for young adults aged 18-39 who are survivors of brain cancer. Participants will take part in a tele-exercise program to help with fatigue caused by cancer treatment.
Recruiting
Examining the Feasibility and Impact of a Clinic-based Food Farmacy and Digital Culinary Medicine Program Among Cancer Survivors Treated in a Safety Net Hospital
NA Houston, Texas NCT06760754
This trial is looking for cancer survivors with food insecurity who were treated at MD Anderson. Participants will take part in a culinary medicine program and may need to complete some assessments.
Recruiting
Active Living After Cancer: Implementation Within Be Well Acres Homes
NA Houston, Texas NCT06907706
This trial is looking for cancer survivors who want to join a physical activity program. Participants should be done with their cancer treatment and meet other specific criteria.
Recruiting
Connect for Cancer Prevention Study (Connect)
N/A Denver, Colorado +4 sites NCT04609072
This trial is looking for adults between 30 and 70 years old who have never had cancer. Participants will help researchers learn about cancer risk by answering online health surveys and donating blood, urine, and saliva samples.
Recruiting
TREC@TAMU Cancer Prevention Registry and Repository
N/A Bryan, Texas NCT06826014
This trial is looking for adults who want to help with cancer research. Participants will provide health and genetic information and share blood and urine samples for future studies.
Recruiting
Prospective Study to Assess a Diagnostic Aid for Cancer
N/A Coronado, California +4 sites NCT07046260
This trial is looking for people aged 45 and older who have symptoms that might suggest cancer. Participants will take a blood test and may also have additional standard tests to see if cancer is present.
Recruiting
Perceptions of Hospital Care at Home for Patients With Cancer: A Qualitative Study of Cancer Providers, Patients and Caregivers.
N/A Houston, Texas NCT05694650
This trial is looking for cancer care providers, patients, and caregivers to share their thoughts on hospital care at home. Participants will be involved in interviews to help plan future care programs for cancer patients at home.
Recruiting
Falcon Real World Evidence Registry
N/A Dallas, Texas +1 sites NCT06589310
This trial is looking for adults aged 50 to 80 who are willing to take the Exact Sciences MCED test for early cancer detection. Participants will need to complete follow-up imaging and surveys electronically.
Recruiting

Where the Cancer studies are in Texas

  • MD Anderson Cancer Center, Houston162 trials
  • M D Anderson Cancer Center, Houston106 trials
  • The University of Texas MD Anderson Cancer Center, Houston67 trials
  • University of Texas MD Anderson Cancer Center, Houston50 trials
  • University of Texas Southwestern Medical Center, Dallas47 trials
  • UT Southwestern/Simmons Cancer Center-Dallas, Dallas46 trials

Counts are recruiting studies listing at least one site in Texas, from ClinicalTrials.gov, refreshed every two days.

Cancer clinical trials in Texas: common questions

How many Cancer clinical trials are recruiting in Texas?
TrialFinder currently lists 1166 recruiting Cancer clinical trials with study sites in Texas. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Cancer clinical trials located in Texas?
Study sites for the Cancer trials listed on this page include Houston, Austin, Irving, Bryan, Dallas. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Cancer clinical trial in Texas?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Cancer trials in Texas also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Cancer clinical trial in Texas?
Each study sets its own criteria based on age, Cancer diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Will I get a placebo instead of cancer treatment?
Almost never. Cancer trials compare a new treatment with the current standard treatment, or add the study drug to standard treatment. When a placebo is used it is on top of standard care, and the consent form states this before you decide.
Can I join a cancer trial if my cancer has spread?
Yes. Many recruiting cancer trials are written for advanced or metastatic disease, including people whose earlier treatments have stopped working. The listing states the stage and prior treatments it accepts.
Do I have to stop my current cancer treatment to join a trial?
It depends on the trial. Some enroll people whose current treatment has stopped working, some add the study drug to the treatment you are on, and some are for people who have not started treatment yet. Ask the study team before changing anything.
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