No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 39
Sex
Any
Study type
Interventional
Purpose
Supportive Care
Participants needed
75 (estimated)
Sponsor
M.D. Anderson Cancer Center · Other
Who this trial is looking for
This trial is looking for young adults aged 18-39 who are survivors of brain cancer. Participants will take part in a tele-exercise program to help with fatigue caused by cancer treatment.
Are You a Good Fit for This Trial?
You may be able to join if
I am between the ages of 18-39 years.
My brain tumor was diagnosed between the ages of 15-39.
I am 6 months to less than 5 years post-treatment.
I have received chemotherapy and radiation for my brain tumor.
I currently engage in less than 150 minutes of physical activity weekly.
I can speak, write, and read in English.
I can provide informed consent.
You may not be able to join if
I do not speak English.
I have an unstable heart or lung condition.
I have had a recent fracture or injury that affects my ability to exercise.
I have a chronic disease or need re-irradiation for my brain tumor.
I have significant cognitive or sensory deficits.
I am pregnant.
I am a prisoner.
I have a developmental disorder or major psychotic illness.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The goal of this research study is to learn about the effects of the RISE-YA intervention on cancer-related fatigue in young adults who are brain cancer survivors.
Trial Locations
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Status
Eligibility Criteria
Inclusion Criteria:
1. Is currently between the ages of 18-39 years
2. Their primary brain tumor was diagnosed at age 15-39 years
3. Is 6 months to \<5 years post curative treatment
4. Has been treated with chemotherapy and radiation, given most patients receive both therapies.
5. Functional Assess…
Inclusion Criteria:
1. Is currently between the ages of 18-39 years
2. Their primary brain tumor was diagnosed at age 15-39 years
3. Is 6 months to \<5 years post curative treatment
4. Has been treated with chemotherapy and radiation, given most patients receive both therapies.
5. Functional Assessment of Chronic Illness therapy (FACIT)-Fatigue ≤ 43. FACIT-Fatigue will be used as a screener because this 13-item scale can be completed relatively quickly in clinic
6. Currently engage in \<150 minutes of PA and \< 2 sessions of muscle strengthening exercise per week (assessed by Godin Leisure-Time PA Questionnaire)
7. Must be able to speak, write, and read English
8. No exercise contraindication as assessed by screening with the Physical Activity Readiness Questionnaire PAR-Q+. In addition, participants' care teams will be notified of their participation in the study.
9. Must be able to provide informed consent/assent.
Exclusion Criteria:
1. Non-English speaking
2. Screen failure for exercise safety
3. Underlying unstable cardiac or pulmonary disease or symptomatic cardiac disease
4. Recent fracture or acute musculoskeletal injury that precludes ability to participate in supervised exercise training sessions
5. History of underlying chronic disease, secondary malignances, germline genetic syndrome, or recurrent disease requiring re-irradiation of the brain
6. Cognitive and/or major sensory deficits that would impede the completion of research activities and assessments as deemed by the clinical team.
7. Self-report of pregnancy
8. Prisoners
9. Documented developmental disorders (e.g., Autism) or major psychotic illness (e.g., schizophrenia)
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