Personalized TMS Treatment for Recovery After Stroke

Real-time Personalized Brain State-dependent TMS After Stroke

Recruiting N/A Interventional Study
Stroke
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Basic Science
Participants needed
37 (estimated)
Sponsor
Sara Hussain · Other
Who this trial is looking for

This trial is looking for people who have some weakness in one arm after having a stroke. Participants will receive a specific type of brain stimulation to see if it helps improve arm function better than standard methods.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have some weakness in one arm after my stroke.
  • I had my stroke at least 6 months ago.
  • I scored more than 24 on the Mini Mental State Exam.
  • I can give my informed consent.

You may not be able to join if

  • I have had a history of other neurological diseases.
  • I have a cardiac pacemaker or similar device.
  • I had a seizure in the last 12 months while taking anti-epilepsy medication.
  • I have experienced adverse reactions to TMS before.
  • I am currently pregnant or planning to get pregnant.
  • I have made recent changes to my medication in the last month.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial
Transcranial magnetic stimulation (TMS) interventions could feasibly strengthen residual corticospinal tract (CST) connections and enhance recovery of paretic upper extremity function after stroke. This project will test whether personalized brain state-dependent TMS can activate the residual corticospinal tract better than standard TMS, and evaluate the relationship between this activation and up…
Trial Locations
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Eligibility Criteria
-Presence of residual upper extremity hemiparesis, defined as any of the following: Fugl Meyer Upper Extremity Score \<66, Wolf Motor Function Test Score \<70, Affected hand performance on the 9-Hole Peg Test \>= 10% worse than unaffected hand, Affected hand pinch, key, or power grip performance \>=…
Contacts

Sara J Hussain, PhD

319-335-1182

sara-hussain@uiowa.edu

CONTACT

Sara J Hussain, PhD

CONTACT